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Uveitis is an inflammation of the uvea, the middle layer of the eye that includes the iris, ciliary body, and choroid. It is caused by genetic factors like HLA-B27 antigen, infections such as Human T-Cell Lymphotropic Virus (HTLV), or autoimmune conditions. The HLA-B27 Antigen test is the most important test for identifying genetic predisposition to uveitis.
Uveitis is caused by genetic factors, infections, autoimmune diseases, and inflammatory conditions. The HLA-B27 antigen is a genetic marker strongly associated with developing uveitis, particularly anterior uveitis affecting the front of the eye. Infections like Human T-Cell Lymphotropic Virus type I (HTLV-I), toxoplasmosis, herpes viruses, and tuberculosis can trigger eye inflammation. Autoimmune conditions such as rheumatoid arthritis, ankylosing spondylitis, and inflammatory bowel disease are also common causes of uveitis.
The HLA-B27 Antigen test is the most important blood test for uveitis because it identifies genetic predisposition to this inflammatory eye condition. Studies show a significantly higher prevalence of HLA-B27 in patients with uveitis, especially those with acute anterior uveitis. If viral infection is suspected, the Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies test is essential for detecting HTLV-related uveitis. The HLA B Low Resolution test provides broader genetic typing that includes HLA-B27 and can reveal additional genetic risk factors. These tests help identify underlying causes and guide your doctor toward the most effective treatment approach.
You should get tested if you experience eye redness, pain, blurred vision, light sensitivity, or floaters that do not improve quickly. Testing is especially important if you have recurrent episodes of eye inflammation, a family history of uveitis or autoimmune diseases, or known conditions like ankylosing spondylitis or inflammatory bowel disease. If you have persistent eye discomfort lasting more than a few days or sudden vision changes, blood testing can help identify genetic factors or infections contributing to your symptoms and prevent potential vision loss.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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