Tomato Allergy Blood Test

What is Tomato allergy?

Tomato allergy is an immune system reaction that occurs when your body mistakenly identifies proteins in tomatoes as harmful substances. It is caused by specific proteins in tomatoes, primarily Lyc e 1, Lyc e 2, and Lyc e 3, which trigger IgG and IgE antibody production. The Food Specific IgG Allergy (Adult) Panel is the most important test for diagnosis because it measures tomato-specific IgG antibodies that indicate immune reactions.

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What causes tomato allergy?

Tomato allergy is caused by your immune system reacting to specific proteins found in tomatoes, including Lyc e 1 (profilin), Lyc e 2 (beta-fructofuranosidase), and Lyc e 3 (lipid transfer protein). When you consume tomatoes or tomato-based products, these proteins trigger your immune system to produce antibodies—primarily IgG and IgE—that identify the proteins as threats. This immune response leads to the release of histamine and other chemicals that cause allergic symptoms ranging from mild skin reactions to severe systemic responses.

What is the best test for tomato allergy?

The Food Specific IgG Allergy (Adult) Panel is the most important test for tomato allergy because it detects elevated levels of tomato-specific IgG antibodies (f25) that indicate an immune reaction to tomato proteins. This comprehensive blood test measures your body's antibody response to tomatoes along with other common food allergens, providing objective evidence of an allergic reaction. The test is particularly valuable when symptoms are unclear or when multiple food sensitivities are suspected, helping you identify trigger foods and develop an effective dietary management plan.

When should I get tested for tomato allergy?

You should get tested if you experience symptoms like hives, skin rashes, itching, swelling of the lips or tongue, digestive issues, or respiratory problems after eating tomatoes or tomato-based products like pasta sauce, ketchup, or pizza. Testing is also important if you have a history of other food allergies or if you notice symptoms that worsen during tomato season when you consume more fresh tomatoes. Getting tested early helps you confirm the diagnosis and avoid potentially severe allergic reactions.

What are the symptoms of tomato allergy?
Tomato allergy symptoms include skin reactions like hives, rashes, itching, and eczema flare-ups. You might experience swelling of the lips, tongue, or throat, along with digestive symptoms such as nausea, vomiting, stomach cramps, and diarrhea. Respiratory symptoms can include coughing, wheezing, nasal congestion, and difficulty breathing. In severe cases, tomato allergy can trigger anaphylaxis, a life-threatening reaction that requires immediate medical attention and causes symptoms like rapid pulse, dizziness, severe breathing difficulty, and loss of consciousness.
Who is at risk for tomato allergy?
People with existing food allergies or a family history of allergies are at higher risk for developing tomato allergy. Those with oral allergy syndrome, particularly individuals allergic to birch or grass pollen, often develop cross-reactive allergies to tomatoes due to similar protein structures. Children with eczema or asthma have increased susceptibility to food allergies including tomatoes. People with latex allergies may also experience tomato allergy due to cross-reactivity between latex proteins and tomato proteins, a condition known as latex-fruit syndrome.
What happens if tomato allergy is left untreated?
If tomato allergy is left untreated and you continue consuming tomatoes, your allergic reactions may become more severe over time. Repeated exposure can lead to chronic inflammation, persistent skin conditions like eczema, ongoing digestive problems, and increased risk of developing additional food sensitivities. Without proper diagnosis and management, you remain at risk for anaphylaxis, a potentially fatal allergic reaction. Undiagnosed tomato allergy can also contribute to nutritional deficiencies if you avoid multiple foods without proper guidance, and chronic inflammation may impact your overall health and quality of life.
Can tomato allergy be diagnosed with a blood test?
Yes, tomato allergy can be diagnosed with a blood test that measures specific IgG and IgE antibodies to tomato proteins. The Food Specific IgG Allergy (Adult) Panel detects elevated levels of tomato-specific IgG antibodies, providing objective evidence of an immune reaction. Blood testing is particularly useful because it is safe (no risk of triggering a severe allergic reaction during testing), can test for multiple allergens simultaneously, and provides quantifiable results that help track your immune response over time. Blood tests complement clinical history and can be done without stopping antihistamine medications, unlike skin prick tests.
How is tomato allergy treated?
Tomato allergy is treated primarily through strict avoidance of tomatoes and tomato-containing products, including fresh tomatoes, cooked tomatoes, tomato sauce, ketchup, salsa, and processed foods with tomato ingredients. Your doctor may prescribe antihistamines for mild reactions and an epinephrine auto-injector for severe allergies or risk of anaphylaxis. Reading food labels carefully is essential since tomatoes appear in many unexpected products. Working with an allergist and registered dietitian helps ensure you maintain proper nutrition while avoiding trigger foods and may help identify cross-reactive foods like potatoes, eggplants, and peppers that share similar proteins.
How can I prevent tomato allergy?
While you cannot prevent developing tomato allergy if you are genetically predisposed, you can prevent allergic reactions by strictly avoiding tomatoes and tomato-based products. Read ingredient labels carefully and watch for tomato in various forms including tomato paste, puree, concentrate, and lycopene. When dining out, inform restaurant staff about your allergy and ask about ingredients in sauces and dishes. Carry an epinephrine auto-injector if prescribed and wear a medical alert bracelet. For those with oral allergy syndrome, cooking tomatoes may reduce allergic reactions since heat denatures some proteins, though this does not work for everyone with tomato allergy.
What can I do at home for tomato allergy?
At home, you can manage tomato allergy by creating a tomato-free kitchen and finding suitable substitutes in your recipes. Replace tomato sauce with alternatives like roasted red pepper sauce, beet-based sauces, or cream-based sauces. Keep antihistamines on hand for accidental mild exposures and ensure your epinephrine auto-injector is easily accessible and not expired. Maintain a food diary to track any reactions and identify hidden sources of tomato in your diet. Consider taking quercetin and vitamin C supplements, which have natural antihistamine properties, though always consult your healthcare provider before starting supplements. Educate family members about your allergy and establish safe food preparation practices.
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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Food Specific IgG Allergy (Adult) Panel
Google reviews 505 reviews
$1,216 $948
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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