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A testosterone-producing tumor is a rare hormone-secreting growth that develops in the adrenal glands, ovaries, or testes. It is caused by abnormal cells that produce excessive amounts of testosterone, leading to dramatically elevated hormone levels in the bloodstream. The Testosterone Total LC/MS/MS test is the most important test for diagnosis because it accurately measures total testosterone levels that become significantly elevated with these tumors.
Testosterone-producing tumors are caused by abnormal cell growth in hormone-secreting tissues including the adrenal glands, ovaries, or testes. These tumors develop when cells begin dividing uncontrollably and producing excessive amounts of testosterone independent of normal hormonal regulation. While most cases occur spontaneously without a clear cause, some may be associated with genetic conditions or hormonal imbalances that trigger abnormal cell growth in these endocrine tissues.
The Testosterone Total LC/MS/MS test is the most important test for testosterone-producing tumors because it uses advanced mass spectrometry technology to accurately measure total testosterone levels in the blood. This test can detect the dramatically elevated testosterone levels that occur when these tumors overproduce hormones. The Testosterone, Free, LC/MS/MS test is also essential because it measures the active, unbound testosterone that becomes extremely elevated with hormone-secreting tumors. Together, these tests provide comprehensive hormone assessment that helps identify abnormal testosterone production requiring further imaging studies to locate the tumor source.
You should get tested if you experience unexplained symptoms of excess testosterone such as rapid onset of masculine features in women including facial hair growth, deepening voice, or irregular periods. Men should seek testing for unexplained aggression, mood changes, or premature puberty in young boys. Testing is particularly important when these symptoms develop suddenly over weeks to months rather than gradually, as this rapid change often indicates a hormone-secreting tumor rather than other hormonal conditions.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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