Skin Cancer Blood Test

What is Skin Cancer?

Skin cancer is an abnormal growth of skin cells caused by DNA damage from ultraviolet radiation exposure, typically from sun or tanning beds. It is caused by mutations in skin cell DNA that trigger uncontrolled cell division, with basal cell carcinoma, squamous cell carcinoma, and melanoma being the three main types. The Vitamin B3 (Nicotinamide) blood test is the most important test for assessing protective nutritional factors that may reduce skin cancer risk.

RECOMMENDED TEST Vitamin B3
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What causes skin cancer?

Skin cancer is caused by DNA damage to skin cells from ultraviolet (UV) radiation exposure, primarily from sunlight and tanning beds. When UV rays penetrate the skin, they damage the genetic material in skin cells, causing mutations that make cells grow uncontrollably. Other contributing factors include fair skin with less protective melanin, a history of severe sunburns, excessive sun exposure over time, family history of skin cancer, weakened immune system, and exposure to certain chemicals like arsenic. People with many moles or unusual moles are also at higher risk for melanoma, the deadliest form of skin cancer.

What is the best test for skin cancer?

The Vitamin B3 (Nicotinamide) test is the most important blood test for assessing protective nutritional factors against skin cancer because it measures nicotinamide levels that have been proven to reduce the development of new skin cancers and precancerous actinic keratoses. While skin cancer diagnosis requires a skin biopsy performed by a dermatologist, the Vitamin B3 test helps evaluate your nutritional defense against skin cancer development. Research shows that adequate nicotinamide levels support DNA repair in sun-damaged skin cells and reduce inflammation that contributes to cancer formation. This test is valuable for people with a history of skin cancer, multiple precancerous lesions, or those at high risk who want to optimize their preventive nutrition strategy.

When should I get tested for skin cancer risk factors?

You should get tested if you have a history of multiple skin cancers or precancerous actinic keratoses, if you have fair skin and significant sun exposure throughout your life, if you are undergoing preventive treatment for skin cancer, or if you want to assess your nutritional protection against skin cancer development. Testing Vitamin B3 levels is particularly important if you have been advised by your dermatologist to take nicotinamide supplements for skin cancer prevention, as it helps ensure you maintain therapeutic levels. You should also consider testing if you have a weakened immune system, a family history of skin cancer, or if you have had organ transplantation, as these conditions increase skin cancer risk significantly.

What are the symptoms of skin cancer?
Skin cancer symptoms include a new growth or sore that does not heal within a few weeks, a spot or mole that changes in size, shape, or color, a shiny or waxy bump on the skin, a flat, flesh-colored or brown scar-like lesion, or a mole that bleeds, itches, or becomes painful. Melanoma warning signs follow the ABCDE rule: Asymmetry (one half does not match the other), Border irregularity (edges are ragged or blurred), Color variation (multiple colors within one spot), Diameter larger than a pencil eraser, and Evolving (changing in size, shape, or color over time). Any persistent skin change, unusual growth, or non-healing sore should be evaluated by a dermatologist promptly, as early detection dramatically improves treatment outcomes.
Who is at risk for skin cancer?
People at highest risk for skin cancer include those with fair skin, light hair, and blue or green eyes, as they have less protective melanin. Other risk factors include a history of sunburns (especially blistering sunburns in childhood), excessive cumulative sun exposure, regular tanning bed use, living at high altitudes or in sunny climates, having many moles or atypical moles, family or personal history of skin cancer, weakened immune system (such as organ transplant recipients or those on immunosuppressive medications), occupational exposure to chemicals like arsenic or coal tar, and certain genetic conditions like xeroderma pigmentosum. Age also plays a role, as skin cancer risk increases with cumulative sun exposure over a lifetime, though melanoma is increasingly common in younger people.
What happens if skin cancer is left untreated?
If skin cancer is left untreated, it can grow deeper into the skin and surrounding tissues, causing disfigurement and requiring more extensive surgery. Basal cell carcinoma can destroy nearby skin, bone, and cartilage, particularly dangerous near the eyes, ears, and nose. Squamous cell carcinoma can spread to lymph nodes and distant organs if not treated, becoming life-threatening. Melanoma is the most dangerous type and can metastasize rapidly to vital organs like the brain, lungs, liver, and bones, becoming fatal once it spreads. Even non-melanoma skin cancers can cause significant complications including nerve damage, functional impairment, and chronic wounds. Early detection and treatment result in cure rates exceeding 95% for most skin cancers, making timely evaluation critical.
Can skin cancer be diagnosed with a blood test?
Skin cancer cannot be diagnosed with a blood test. Diagnosis requires visual examination by a dermatologist and confirmation through a skin biopsy, where a tissue sample is examined under a microscope for cancer cells. However, blood tests like the Vitamin B3 test can play a supportive role by assessing nutritional factors that influence skin cancer risk and prevention. For people who already have melanoma, blood tests may be used to check for tumor markers like lactate dehydrogenase (LDH) to monitor disease progression or treatment response, but these are not diagnostic tests. The gold standard for skin cancer detection remains regular full-body skin examinations by a dermatologist combined with biopsy of any suspicious lesions.
How is skin cancer treated?
Skin cancer treatment depends on the type, size, location, and depth of the cancer. Basal cell and squamous cell carcinomas are often treated with surgical excision, Mohs micrographic surgery (which preserves healthy tissue while removing all cancer), curettage and electrodesiccation (scraping and burning), or cryotherapy (freezing). Topical medications like imiquimod or 5-fluorouracil may be used for superficial cancers. Melanoma treatment typically involves surgical removal with wide margins, and may require sentinel lymph node biopsy, immunotherapy, targeted therapy, radiation, or chemotherapy if the cancer has spread. Advanced or metastatic skin cancers may be treated with immunotherapy drugs like pembrolizumab or nivolumab, targeted therapies for specific mutations, or combination approaches. Nicotinamide supplementation is sometimes recommended as an adjunct preventive measure for people with a history of multiple skin cancers.
How can I prevent skin cancer?
You can prevent skin cancer by protecting your skin from UV radiation through daily use of broad-spectrum sunscreen with SPF 30 or higher, wearing protective clothing including wide-brimmed hats and UV-blocking sunglasses, seeking shade especially between 10 AM and 4 PM when UV rays are strongest, and avoiding tanning beds entirely. Perform monthly self-examinations of your skin to detect changes early, and schedule annual full-body skin checks with a dermatologist, especially if you are at high risk. Some people benefit from taking nicotinamide (Vitamin B3) supplements, which research shows can reduce the rate of new skin cancers by about 23% in high-risk individuals. Stay hydrated, eat antioxidant-rich foods, avoid sunburns at all costs, and be extra vigilant if you have fair skin, many moles, or a family history of skin cancer.
What natural remedies help with skin cancer prevention?
Natural approaches to skin cancer prevention include maintaining adequate Vitamin B3 (nicotinamide) levels through diet or supplementation, as research demonstrates it strengthens skin defenses against UV damage and reduces skin cancer development in high-risk individuals. Eating foods rich in antioxidants like berries, leafy greens, tomatoes (which contain lycopene), and green tea helps protect cells from oxidative damage. Vitamin D from safe sun exposure or supplementation supports immune function, though balance is key since excessive sun causes cancer. Omega-3 fatty acids from fish may reduce inflammation associated with skin cancer development. However, these natural approaches should complement, not replace, proven prevention methods like sunscreen, protective clothing, and regular dermatologist visits. Always consult your healthcare provider before starting supplements, especially if you have a history of skin cancer.
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Long story short:
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  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
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Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

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Vitamin B3
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$129 $101
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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