Question 1

What is Sjögren Syndrome?

Accepted Answer

Sjögren Syndrome is an autoimmune disorder that primarily affects the glands responsible for producing tears and saliva, leading to chronic dry eyes and dry mouth. It is caused by the immune system mistakenly attacking moisture-producing glands, with specific autoantibodies like anti-SSA (Ro) and anti-SSB (La) present in most cases. The Anti-Cyclic Citrullinated Peptide 3 (Anti-CCP3) IgG test is the most important test when overlap syndromes with Rheumatoid Arthritis are suspected.

Question 2

What causes Sjögren Syndrome?

Accepted Answer

Sjögren Syndrome is caused by the immune system mistakenly attacking the body's own moisture-producing glands, particularly the lacrimal glands that make tears and salivary glands that produce saliva. This autoimmune attack is characterized by the presence of specific autoantibodies, including anti-SSA (Ro) and anti-SSB (La), which are found in 40-60% of patients. The exact trigger for this immune system malfunction is not fully understood, but genetic factors, hormonal influences, and possibly viral infections like Epstein-Barr virus may play a role in its development.

Question 3

What is the best test for Sjögren Syndrome?

Accepted Answer

The Anti-Cyclic Citrullinated Peptide 3 (Anti-CCP3) IgG test is the most important test for Sjögren Syndrome when overlap with Rheumatoid Arthritis is suspected because it detects CCP antibodies that may be present in patients with both conditions. While the primary diagnostic tests for Sjögren Syndrome are anti-SSA (Ro) and anti-SSB (La) antibodies, the Anti-CCP3 test becomes essential when patients show symptoms of both autoimmune disorders, such as joint pain combined with dry eyes and mouth. This test helps identify overlap syndromes and guides your healthcare provider in developing a comprehensive treatment plan that addresses both conditions.

Question 4

When should I get tested for Sjögren Syndrome?

Accepted Answer

You should get tested if you experience persistent dry eyes that feel gritty or burning, chronic dry mouth that makes swallowing or speaking difficult, or unexplained joint pain and swelling. Testing becomes especially important if you already have another autoimmune condition like lupus or rheumatoid arthritis, as Sjögren Syndrome often occurs alongside these disorders. You should also consider testing if you have dental problems like frequent cavities despite good oral hygiene, swollen salivary glands, or persistent fatigue that interferes with daily activities.

Question 5

What are the symptoms of Sjögren Syndrome?

Accepted Answer

The most common symptoms of Sjögren Syndrome are dry eyes that feel gritty, sandy, or burning, and dry mouth that makes it difficult to swallow dry foods or speak for long periods. You might also experience swollen salivary glands near your jaw, dental cavities and tooth decay, persistent dry cough, vaginal dryness, and skin rashes. Many people with Sjögren Syndrome also feel extreme fatigue, have joint pain and stiffness similar to arthritis, and may notice their eyes are more sensitive to light or have blurred vision.

Question 6

Who is at risk for Sjögren Syndrome?

Accepted Answer

Women are nine times more likely than men to develop Sjögren Syndrome, with most cases diagnosed after age 40, though it can occur at any age. You are at higher risk if you already have another autoimmune disease like rheumatoid arthritis, lupus, scleroderma, or thyroid disorders, as Sjögren Syndrome frequently occurs alongside these conditions. Family history also plays a role, with those who have relatives with autoimmune diseases having an increased risk of developing the condition themselves.

Question 7

What happens if Sjögren Syndrome is left untreated?

Accepted Answer

Untreated Sjögren Syndrome can lead to serious complications affecting multiple organs and systems. The chronic dry eyes can result in corneal damage, ulcers, and vision problems, while persistent dry mouth significantly increases the risk of tooth decay, gum disease, and oral infections like thrush. Beyond these primary symptoms, untreated Sjögren Syndrome can cause kidney problems, lung inflammation, nerve damage causing numbness and tingling, and in rare cases, an increased risk of developing lymphoma, a type of cancer affecting the lymphatic system.

Question 8

Can Sjögren Syndrome be diagnosed with a blood test?

Accepted Answer

Yes, blood tests are essential for diagnosing Sjögren Syndrome and detecting the specific autoantibodies your immune system produces against your own tissues. The most important blood tests measure anti-SSA (Ro) and anti-SSB (La) antibodies, which are present in 40-60% of Sjögren Syndrome patients. Blood tests also check for elevated inflammatory markers like ESR (erythrocyte sedimentation rate) and rheumatoid factor, and the Anti-CCP3 IgG test helps identify patients who have overlap with Rheumatoid Arthritis, allowing for more accurate diagnosis and targeted treatment.

Question 9

How is Sjögren Syndrome treated?

Accepted Answer

Treatment for Sjögren Syndrome focuses on relieving symptoms and preventing complications since there is no cure for the condition. For dry eyes, doctors recommend artificial tears, prescription eye drops like cyclosporine or lifitegrast, and sometimes tear duct plugs to retain natural moisture. Dry mouth is managed with saliva substitutes, prescription medications like pilocarpine or cevimeline that stimulate saliva production, and drinking water frequently throughout the day. If you have systemic symptoms like joint pain or organ involvement, your doctor may prescribe immunosuppressive medications like hydroxychloroquine, methotrexate, or corticosteroids to reduce inflammation and control the autoimmune response.

Question 10

How can I prevent Sjögren Syndrome?

Accepted Answer

There is no known way to prevent Sjögren Syndrome since it is an autoimmune disorder with genetic and environmental factors that are not fully understood. However, if you have other autoimmune conditions or a family history of autoimmune diseases, staying aware of early symptoms can lead to earlier diagnosis and treatment. Maintaining good overall health through a balanced diet, managing stress, avoiding smoking, and staying hydrated may support your immune system, though these measures cannot prevent the condition from developing if you are genetically predisposed.

Question 11

What can I do at home for Sjögren Syndrome?

Accepted Answer

You can manage Sjögren Syndrome symptoms at home by using artificial tears frequently throughout the day, using a humidifier to add moisture to the air in your home, and sipping water constantly to keep your mouth moist. Chewing sugar-free gum or sucking on sugar-free candy stimulates saliva production, while avoiding caffeine, alcohol, and smoking helps prevent further drying of your mouth and eyes. Practicing good oral hygiene with fluoride toothpaste and regular dental checkups is essential to prevent tooth decay, and wearing wraparound sunglasses outdoors protects your eyes from wind and sun that can worsen dryness.

Question 12

How’s this work?

Accepted Answer

Getting your blood test with us is easy, private & backed by the power of science.Long story short:
            
                In the test options, use the filters or search box to narrow your choices and find the test you want.
                If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
                Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
                If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
                When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
                Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
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Question 13

How do I know which test to get?

Accepted Answer

In the test options, find the test you want.
            If you’re not sure which test to get, we can lend a hand in finding the right option.
            Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

Question 14

When will my lab results be available?

Accepted Answer

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know.
            After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop!
            If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Question 15

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Accepted Answer

Absolutely! We totally understand that errors can happen. No worries, we're here to help you.
            Just reach out to us via text at 754-799-7833 or shoot us an email at
            support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update.
            Our awesome team will jump right in and make sure everything is sorted out and accurate for you.
            There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.
            Our lab requires an address to be listed to generate an order.

Question 16

Do you accept health insurance?

Accepted Answer

Only HSA & FSA is accepted.
            Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.
            This policy applies to all insurance companies, including federal health insurance programs like Medicare.
            If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Question 17

Can I cancel my order?

Accepted Answer

Yes.
            We get it – sometimes your needs change.
            As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.
            If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
            You can read more about our cancellation policy here.

Question 18

How can I find a lab location near me?

Accepted Answer

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached!
            You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).
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            If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Sjögren Syndrome Blood Test

What is Sjögren Syndrome?

What causes Sjögren Syndrome?

What is the best test for Sjögren Syndrome?

When should I get tested for Sjögren Syndrome?

References

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