Sickle cell anemia is a genetic blood disorder where red blood cells become rigid and sickle-shaped instead of flexible and round. It is caused by a mutation in the HBB gene that produces abnormal hemoglobin S, which distorts red blood cell shape and blocks blood flow. The Sickle Cell Test is the most important test for diagnosis because it detects the presence of hemoglobin S in the blood.
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Sickle cell anemia is caused by a genetic mutation in the HBB gene that produces abnormal hemoglobin called hemoglobin S. This mutation is inherited from both parents, meaning you must receive the sickle cell gene from both your mother and father to develop the disease. When hemoglobin S replaces normal hemoglobin A, red blood cells lose their flexible, round shape and become rigid and crescent-shaped like a sickle, which causes them to get stuck in small blood vessels and break down prematurely.
The Sickle Cell Test is the most important test for sickle cell anemia because it specifically detects the presence of abnormal hemoglobin S in your blood. This screening test provides a definitive diagnosis by identifying whether you have sickle cell disease or are a carrier of the sickle cell trait. For monitoring disease complications, the Viscosity, Serum test is also valuable because it measures blood thickness, which increases when rigid sickle cells stick together and helps assess how severely blood flow is affected. Together, these tests provide comprehensive diagnosis and ongoing monitoring of the condition.
You should get tested if you experience frequent episodes of severe pain (called pain crises), unexplained fatigue and weakness, frequent infections, delayed growth in children, or vision problems. Testing is especially important if you have African, Mediterranean, Middle Eastern, or South Asian ancestry, as sickle cell anemia is more common in these populations. You should also get tested before pregnancy if you or your partner might be carriers, or if you have a family history of sickle cell disease or trait.
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What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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