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Shingles (herpes zoster) is a painful viral infection characterized by a blistering rash that typically appears on one side of the body. It is caused by the reactivation of the varicella-zoster virus (VZV), the same virus that causes chickenpox, which remains dormant in nerve tissue after the initial infection. The Varicella-Zoster Virus (VZV) Antibodies, IgG test is the most important test for confirming immune response and viral exposure related to shingles.
Shingles is caused by the reactivation of the varicella-zoster virus (VZV), the same virus responsible for chickenpox. After you recover from chickenpox, usually during childhood, the virus remains dormant in nerve tissue near your spinal cord and brain. Years or decades later, the virus can reactivate and travel along nerve pathways to your skin, producing the painful rash characteristic of shingles. This reactivation typically occurs when your immune system weakens due to aging, stress, certain medications, or other health conditions that compromise immunity.
The Varicella-Zoster Virus (VZV) Antibodies, IgG test is the most important blood test for shingles because it measures your immune system's antibody response to the varicella-zoster virus. This test confirms whether you have been exposed to VZV and helps assess your immune status, which is particularly valuable when the clinical presentation is unclear or in cases where confirmation of viral exposure is needed. Elevated VZV IgG antibody levels indicate that your body has mounted an immune response to the virus, supporting the diagnosis of shingles. While shingles is primarily diagnosed through clinical examination of the characteristic rash, this blood test provides essential supporting information about viral activity and immune response.
You should get tested if you develop a painful, blistering rash on one side of your body, especially if you have a weakened immune system or are over 50 years old. Testing is also recommended if you experience burning, tingling, or numbness in a specific area before a rash appears, or if your healthcare provider needs to confirm VZV exposure in atypical cases. Additionally, if you have risk factors such as cancer, HIV, or are taking immunosuppressive medications, testing can help your doctor understand your immune status and guide appropriate treatment decisions.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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