Renal Dysfunction Blood Test

What is Renal Dysfunction?

Renal dysfunction is impaired kidney function that affects the body's ability to filter waste products and maintain electrolyte balance. It is caused by factors including chronic lead exposure, diabetes, hypertension, autoimmune diseases, and nephrotoxic medications. The Lead (Venous), OSHA and Zinc Protoporphyrin Evaluation is the most important test for identifying environmental causes of kidney damage and nephrotoxicity.

RECOMMENDED TEST Lead (Venous), OSHA and Zinc Protoporphyrin Evaluation
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What causes renal dysfunction?

Renal dysfunction is caused by conditions that damage the kidney's filtering units called nephrons. Common causes include diabetes, which damages blood vessels in the kidneys through high blood sugar levels, and hypertension, which strains kidney blood vessels over time. Environmental toxins like lead, mercury, and cadmium can cause nephrotoxicity, while autoimmune diseases such as lupus attack kidney tissue directly. Medications including NSAIDs, certain antibiotics, and chemotherapy drugs can also impair kidney function, as can urinary tract obstructions and chronic infections.

What is the best test for renal dysfunction?

The Lead (Venous), OSHA and Zinc Protoporphyrin Evaluation is the most important test for identifying environmental causes of renal dysfunction because it detects lead levels and zinc protoporphyrin, which increases when lead interferes with normal blood cell production and kidney function. Chronic lead exposure is a known cause of nephrotoxicity that leads to nephropathy and chronic kidney disease, making this test essential for anyone with occupational exposure to lead or those living in environments with potential lead contamination. This test should be combined with standard kidney function tests like creatinine, blood urea nitrogen (BUN), and glomerular filtration rate (GFR) to get a complete picture of kidney health and identify specific causes of dysfunction.

When should I get tested for renal dysfunction?

You should get tested if you notice symptoms like persistent fatigue, swelling in your ankles or feet, changes in urination patterns (frequency, color, or amount), or unexplained nausea and loss of appetite. Testing is especially important if you have risk factors such as diabetes, high blood pressure, a family history of kidney disease, or occupational exposure to heavy metals like lead. You should also get tested if you work in construction, battery manufacturing, metal recycling, or painting industries where lead exposure is common, or if you live in older homes with lead pipes or lead-based paint.

What are the symptoms of renal dysfunction?
Symptoms of renal dysfunction include persistent fatigue and weakness, swelling in the ankles, feet, or hands due to fluid retention, and changes in urination such as foamy urine, decreased urine output, or increased nighttime urination. You might experience nausea, vomiting, loss of appetite, difficulty concentrating, muscle cramps, dry and itchy skin, and shortness of breath. Many people with early-stage kidney dysfunction have no symptoms at all, which is why blood testing is so important for early detection before permanent damage occurs.
Who is at risk for renal dysfunction?
People with diabetes and high blood pressure are at highest risk for renal dysfunction, as these conditions damage kidney blood vessels over time. Those with a family history of kidney disease, individuals over age 60, and people with heart disease or obesity face increased risk. Workers in industries with heavy metal exposure, including construction, battery manufacturing, metal recycling, and painting, are at risk for lead-induced kidney damage. People who regularly use NSAIDs, certain antibiotics, or have autoimmune diseases like lupus also have elevated risk for developing kidney problems.
What happens if renal dysfunction is left untreated?
Untreated renal dysfunction progresses to chronic kidney disease and eventually end-stage renal disease requiring dialysis or kidney transplant. As kidney function declines, dangerous levels of waste products and fluid accumulate in your body, leading to cardiovascular disease, stroke, bone disease, anemia, and electrolyte imbalances that can cause irregular heartbeat or sudden cardiac death. You may develop severe complications including pulmonary edema (fluid in the lungs), metabolic acidosis, and uremia (toxic buildup of waste in the blood). Early detection and treatment can slow or stop this progression, making timely blood testing critical for preserving kidney function.
Can renal dysfunction be diagnosed with a blood test?
Yes, renal dysfunction is diagnosed primarily through blood tests that measure waste products and electrolytes. Key blood tests include serum creatinine, which indicates how well kidneys filter waste, and blood urea nitrogen (BUN), which measures urea levels in the blood. These values are used to calculate your estimated glomerular filtration rate (GFR), the most accurate indicator of kidney function. Additional blood tests check electrolyte levels (sodium, potassium, calcium, phosphorus), complete blood count for anemia, and specific toxins like lead that can cause kidney damage. Blood tests are combined with urine tests for a complete kidney health assessment.
How is renal dysfunction treated?
Treatment for renal dysfunction focuses on managing underlying causes and slowing disease progression. This includes strict blood sugar control for diabetics, blood pressure management with ACE inhibitors or ARBs that protect kidneys, and dietary modifications limiting protein, sodium, potassium, and phosphorus intake. If lead or other toxins are identified as causes, chelation therapy may be used to remove heavy metals from the body, along with eliminating ongoing exposure sources. Advanced cases may require erythropoietin injections for anemia, phosphate binders, vitamin D supplements, and ultimately dialysis or kidney transplant for end-stage disease. Regular monitoring through blood tests ensures treatment effectiveness.
How can I prevent renal dysfunction?
Prevent renal dysfunction by controlling blood sugar if you have diabetes and maintaining healthy blood pressure below 130/80 mmHg through diet, exercise, and medication if needed. Stay well-hydrated, maintain a healthy weight, avoid smoking, and limit alcohol consumption. Reduce exposure to nephrotoxic substances by using NSAIDs sparingly, avoiding excessive protein intake, and following workplace safety protocols if you work with heavy metals or chemicals. If you live in an older home, test for lead in water and paint, and use protective equipment when working with lead-containing materials. Regular blood testing allows early detection before significant damage occurs.
What can I do at home for renal dysfunction?
At home, follow a kidney-friendly diet low in sodium (under 2,300 mg daily), limit protein to reduce waste buildup, and control potassium and phosphorus intake based on your blood test results. Stay hydrated with water, avoid over-the-counter pain relievers like ibuprofen that damage kidneys, and monitor your blood pressure daily. Exercise regularly with moderate activities like walking to improve cardiovascular health and maintain healthy weight. If lead exposure is identified, remove sources from your home including old paint and lead pipes, use cold water for drinking and cooking, and run tap water for 30 seconds before use to flush out lead particles. Keep all medical appointments and blood test schedules to track kidney function.
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How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

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Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Lead (Venous), OSHA and Zinc Protoporphyrin Evaluation
Google reviews 505 reviews
$335 $261
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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