Recent Chickenpox Infection Blood Test

What is Recent Chickenpox infection?

Recent chickenpox infection is a highly contagious viral illness characterized by an itchy rash and flu-like symptoms. It is caused by the varicella-zoster virus (VZV), which spreads through respiratory droplets and direct contact with the rash. The Varicella-Zoster Virus Antibodies IgG test is the most important test for confirming recent infection by detecting rising antibody levels in the blood.

RECOMMENDED TEST Varicella-Zoster Virus (VZV) Antibodies, IgG (Chickenpox)
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What causes recent chickenpox infection?

Recent chickenpox infection is caused by the varicella-zoster virus (VZV), a highly contagious member of the herpesvirus family. The virus spreads easily through respiratory droplets when an infected person coughs or sneezes, and through direct contact with fluid from chickenpox blisters. You can catch chickenpox from someone who is infected from 1-2 days before their rash appears until all blisters have crusted over, making it extremely contagious during this period.

What is the best test for recent chickenpox infection?

The Varicella-Zoster Virus Antibodies IgG test is the most important test for confirming recent chickenpox infection because it detects and measures the specific antibodies your immune system produces in response to VZV. This test works by comparing antibody levels between two blood samples taken two weeks apart - a four-fold or greater increase in IgG antibody levels strongly confirms a recent infection. This testing approach is particularly valuable when clinical symptoms are unclear, when you need documentation of recent infection for medical or occupational purposes, or when confirming exposure after contact with infected individuals.

When should I get tested for recent chickenpox infection?

You should get tested if you have been exposed to someone with chickenpox and need to confirm whether you have been infected, especially if you are pregnant, have a weakened immune system, or work in healthcare or childcare settings. Testing is also recommended if you develop symptoms like fever, fatigue, and an itchy rash but need definitive confirmation, or if you require documentation of recent infection for work or school clearance. Getting tested within the appropriate timeframe helps ensure accurate results and allows for proper medical management if needed.

What are the symptoms of recent chickenpox infection?
Recent chickenpox infection typically begins with flu-like symptoms including fever, headache, fatigue, and loss of appetite 1-2 days before the rash appears. The characteristic itchy rash starts as small red bumps that develop into fluid-filled blisters, which eventually crust over and scab. You will notice new waves of blisters appearing over several days, so you might have bumps, blisters, and scabs all at the same time on different parts of your body. The rash usually starts on the face, chest, and back before spreading to the rest of the body.
Who is at risk for recent chickenpox infection?
Anyone who has never had chickenpox or received the chickenpox vaccine is at risk for infection. Young children, especially those under 12 years old, are most commonly affected, though unvaccinated adults can also get chickenpox. People with weakened immune systems, pregnant women who have never had chickenpox, and newborn babies whose mothers are not immune face higher risks of severe complications. Healthcare workers, teachers, and childcare providers who have not been vaccinated or previously infected are also at increased risk due to frequent exposure to the virus.
What happens if recent chickenpox infection is left untreated?
While most healthy children recover from chickenpox without complications, leaving the infection unmanaged can lead to serious problems. Bacterial skin infections can develop when scratching the blisters introduces bacteria into the wounds, potentially causing cellulitis or abscesses. More severe complications include pneumonia, brain inflammation (encephalitis), bleeding problems, bloodstream infections, and dehydration. In adults, pregnant women, newborns, and people with weakened immune systems, untreated chickenpox can be life-threatening and may cause birth defects if contracted during pregnancy.
Can recent chickenpox infection be diagnosed with a blood test?
Yes, recent chickenpox infection can be confirmed with a blood test that measures varicella-zoster virus antibodies. The VZV IgG antibody test detects the immune response to the virus, and when two blood samples taken two weeks apart show a significant rise in antibody levels, this confirms recent infection. Blood testing is particularly useful when the rash is atypical or has already resolved, when you need official documentation of infection, or when confirming exposure in high-risk individuals who may require preventive treatment.
How is recent chickenpox infection treated?
Recent chickenpox infection is primarily treated with supportive care to relieve symptoms and prevent complications. You can manage itching with calamine lotion, oatmeal baths, and antihistamines, while acetaminophen helps reduce fever (never use aspirin in children with chickenpox). Antiviral medications like acyclovir may be prescribed for high-risk patients, adults, or those with severe infection if started within 24 hours of rash onset. Keeping fingernails trimmed, staying hydrated, and avoiding scratching the blisters helps prevent bacterial infections and scarring.
How can I prevent recent chickenpox infection?
The most effective way to prevent chickenpox infection is through vaccination with the varicella vaccine, which is typically given in two doses - the first at 12-15 months of age and the second at 4-6 years old. If you have never had chickenpox or been vaccinated, getting the vaccine as an adult can still provide protection. Avoiding close contact with infected individuals, especially during the contagious period from 1-2 days before the rash appears until all blisters have crusted over, helps prevent transmission. If you are exposed to chickenpox and are not immune, post-exposure vaccination within 3-5 days may prevent or reduce the severity of infection.
What can I do at home for recent chickenpox infection?
At home, you can manage chickenpox symptoms by taking lukewarm oatmeal baths to soothe itchy skin and applying calamine lotion to the rash. Keep your fingernails short and clean to minimize skin damage from scratching, and consider wearing soft cotton gloves at night. Stay cool and avoid activities that cause sweating, as heat can worsen itching. Drink plenty of fluids to stay hydrated, eat soft foods if mouth sores develop, and get adequate rest to help your immune system fight the virus. Isolate yourself from others, especially pregnant women and people with weakened immune systems, until all blisters have completely crusted over.
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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Varicella-Zoster Virus (VZV) Antibodies, IgG (Chickenpox)
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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