Preterm Delivery Blood Work

What is Preterm delivery?

Preterm delivery is birth that occurs before 37 weeks of pregnancy, affecting approximately 10% of pregnancies. It is caused by infections like Trichomonas vaginalis, cervical insufficiency, inflammation, and placental complications that trigger early labor. The Trichomonas vaginalis RNA Qualitative TMA test is the most important test for detecting treatable infections that significantly increase preterm delivery risk.

RECOMMENDED TEST Trichomonas vaginalis RNA, Qualitative, TMA (Female)
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What causes preterm delivery?

Preterm delivery is caused by infections such as Trichomonas vaginalis, bacterial vaginosis, and urinary tract infections that trigger inflammation in the reproductive tract. Additional causes include cervical insufficiency where the cervix opens too early, placental problems like placenta previa or abruption, chronic conditions such as diabetes and high blood pressure, and lifestyle factors including smoking and drug use. Multiple pregnancies with twins or triplets also significantly increase the risk of early labor.

What is the best test for preterm delivery?

The Trichomonas vaginalis RNA Qualitative TMA test is the most important test for preterm delivery prevention because it detects Trichomonas vaginalis, a common sexually transmitted infection that significantly increases early labor risk through inflammation and reproductive tract changes. This highly sensitive RNA test identifies the infection even when symptoms are absent, allowing for immediate antibiotic treatment during pregnancy. Additional screening tests like cervical length ultrasound, fetal fibronectin testing, and cultures for Group B Streptococcus and bacterial vaginosis help create a comprehensive risk assessment and prevention strategy.

When should I get tested for preterm delivery?

You should get tested if you have had a previous preterm birth, are experiencing unusual vaginal discharge or pelvic discomfort, have a history of cervical procedures or surgery, are pregnant with multiples, or notice symptoms like regular contractions before 37 weeks. Testing is especially important during the second trimester between 16-24 weeks when intervention can be most effective. If you have risk factors like chronic health conditions, a short cervix detected on ultrasound, or a sexually transmitted infection history, discuss early screening with your healthcare provider.

What are the symptoms of preterm delivery?
Symptoms of preterm delivery include regular or frequent contractions that cause your belly to tighten every 10 minutes or more, constant low backache or pelvic pressure, menstrual-like cramps in the lower abdomen, and fluid leaking from your vagina. You might notice increased vaginal discharge that is watery, mucus-like, or blood-tinged, along with a feeling that your baby is pushing down. Some women experience abdominal cramping with or without diarrhea, or simply a persistent feeling that something is not right with their pregnancy.
Who is at risk for preterm delivery?
Women at highest risk include those who have had a previous preterm birth, are pregnant with twins or triplets, or have a short cervix detected on ultrasound. Risk increases with cervical or uterine abnormalities, untreated infections like Trichomonas vaginalis or bacterial vaginosis, chronic health conditions including diabetes and high blood pressure, and being underweight or overweight before pregnancy. African American women face elevated risk, as do those under 17 or over 35 years old, women with high stress levels, those who smoke or use drugs, and anyone with a history of multiple abortions or miscarriages.
What happens if preterm delivery is left untreated?
Untreated preterm delivery leads to babies being born with underdeveloped organs, particularly the lungs, brain, and digestive system. Premature infants face serious complications including respiratory distress syndrome, brain hemorrhages, vision and hearing problems, and feeding difficulties that require extended NICU stays. Long-term consequences include cerebral palsy, developmental delays, learning disabilities, and chronic health conditions like asthma. The earlier the delivery, the greater the risk of infant death or lifelong disabilities, with babies born before 28 weeks facing the most critical outcomes.
Can preterm delivery be diagnosed with a blood test?
Blood tests cannot directly predict preterm delivery, but they identify treatable risk factors that increase early labor chances. The Trichomonas vaginalis RNA test detects sexually transmitted infections that cause inflammation leading to premature labor. Healthcare providers use blood tests to check for anemia, diabetes, thyroid problems, and immune system issues that contribute to preterm delivery risk. Combined with cervical length ultrasounds and fetal fibronectin testing, blood work helps create a comprehensive risk profile that guides prevention strategies like progesterone supplementation or cervical cerclage procedures.
How is preterm delivery treated?
Treatment focuses on delaying delivery and preparing the baby for early birth. Tocolytic medications temporarily stop contractions, giving time for corticosteroid injections that rapidly mature the baby's lungs, reducing respiratory complications. Magnesium sulfate protects the baby's developing brain from neurological damage. If infections like Trichomonas vaginalis are detected, immediate antibiotic treatment eliminates the inflammatory trigger. Women with a short cervix may receive progesterone supplementation or a cervical cerclage, a stitch that holds the cervix closed. Strict bed rest, hospitalization for monitoring, and avoiding physical activity help prevent further labor progression.
How can I prevent preterm delivery?
Prevention starts with regular prenatal care beginning in the first trimester to identify and treat risk factors early. Get tested and treated for infections like Trichomonas vaginalis, bacterial vaginosis, and urinary tract infections that trigger inflammation. Maintain a healthy weight, eat a balanced diet rich in folic acid and omega-3 fatty acids, and avoid smoking, alcohol, and recreational drugs completely. If you have had a previous preterm birth, discuss progesterone supplementation with your healthcare provider. Manage chronic conditions like diabetes and high blood pressure carefully, reduce stress through adequate rest, and space pregnancies at least 18 months apart.
What can I do at home for preterm delivery?
At home, stay well-hydrated by drinking at least eight glasses of water daily, as dehydration can trigger contractions. Rest frequently in a left-side lying position to improve blood flow to the uterus and reduce pressure on the cervix. Monitor your body for warning signs like regular contractions, pelvic pressure, or unusual discharge, and contact your healthcare provider immediately if these occur. Reduce physical activity and avoid heavy lifting, sexual intercourse if advised, and standing for long periods. Practice stress-reduction techniques like gentle prenatal yoga, meditation, and deep breathing exercises, and ensure you get adequate sleep every night.
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Trichomonas vaginalis RNA, Qualitative, TMA (Female)
Google reviews 505 reviews
$179 $140
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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