Preeclampsia Blood Test

What is Preeclampsia?

Preeclampsia is a serious pregnancy complication characterized by high blood pressure and organ damage, most commonly affecting the liver and kidneys. It is caused by abnormal placental development and blood clotting disorders that restrict blood flow to the placenta. The Factor V Leiden Mutation Analysis is the most important test for identifying genetic risk factors that increase the likelihood of developing preeclampsia.

RECOMMENDED TEST Factor V (Leiden) Mutation Analysis
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What causes preeclampsia?

Preeclampsia is caused by abnormal development of the placenta and blood vessels during pregnancy, combined with genetic clotting disorders like Factor V Leiden mutation. When the placenta does not develop properly, it restricts blood flow and triggers an inflammatory response that leads to high blood pressure and protein leaking into the urine. Women with blood clotting mutations face higher risk because these conditions further compromise placental function and blood circulation to the developing baby.

What is the best test for preeclampsia?

The Factor V Leiden Mutation Analysis is the most important test for preeclampsia risk assessment because it detects a genetic mutation that significantly increases your likelihood of developing this dangerous pregnancy complication. This test identifies whether you carry the Factor V Leiden gene, which causes abnormal blood clotting that can restrict placental blood flow. The Vitamin B2 (Riboflavin) test is also essential as research shows that low riboflavin levels are associated with increased preeclampsia risk. Together, these blood tests help identify women who need closer monitoring during pregnancy to prevent life-threatening complications.

When should I get tested for preeclampsia?

You should get tested if you are planning pregnancy and have a personal or family history of preeclampsia, blood clots, or miscarriages. Testing is especially important if you have risk factors like obesity, diabetes, autoimmune disorders, or are over 35 years old. Women who experienced preeclampsia in a previous pregnancy should absolutely get tested before conceiving again. Ideally, genetic and nutritional testing should be completed before pregnancy or during early pregnancy to allow time for preventive measures and enhanced monitoring.

What are the symptoms of preeclampsia?
Preeclampsia symptoms include persistent headaches that do not respond to pain relievers, vision changes like blurred vision or seeing spots, sudden weight gain and severe swelling in your face and hands, and upper abdominal pain especially under your ribs on the right side. You might also notice decreased urination, nausea or vomiting in the second half of pregnancy, and shortness of breath. Some women develop preeclampsia without obvious symptoms, which is why regular blood pressure monitoring during prenatal visits is critical for early detection.
Who is at risk for preeclampsia?
Women at higher risk for preeclampsia include first-time mothers, those over 35 or under 20 years old, and women carrying multiples like twins or triplets. Your risk increases if you have chronic high blood pressure, kidney disease, diabetes, autoimmune disorders like lupus, or obesity. Genetic factors play a significant role, especially if you carry the Factor V Leiden mutation or have a family history of preeclampsia. Women who had preeclampsia in a previous pregnancy face a 15-20% chance of recurrence, and those with new partners between pregnancies also have elevated risk.
What happens if preeclampsia is left untreated?
Untreated preeclampsia can progress to eclampsia, a life-threatening condition causing seizures that can result in coma or death for both mother and baby. The condition can trigger HELLP syndrome, a severe complication involving breakdown of red blood cells, elevated liver enzymes, and dangerously low platelet counts. Other serious complications include stroke, organ failure affecting the kidneys and liver, placental abruption where the placenta separates from the uterus, and premature birth. For the baby, untreated preeclampsia restricts oxygen and nutrient supply, leading to poor growth, low birth weight, and potentially stillbirth.
Can preeclampsia be diagnosed with a blood test?
Preeclampsia is diagnosed clinically through blood pressure measurements and urine protein tests, not through a single blood test. However, blood tests are essential for assessing risk factors before symptoms develop and monitoring complications once preeclampsia is diagnosed. The Factor V Leiden Mutation Analysis identifies genetic predisposition to blood clotting disorders that increase preeclampsia risk, while the Vitamin B2 test reveals nutritional deficiencies associated with higher risk. During pregnancy, doctors may order liver function tests, kidney function tests, and platelet counts to monitor organ function and detect HELLP syndrome.
How is preeclampsia treated?
Preeclampsia treatment depends on the severity and how far along you are in pregnancy, with delivery being the only definitive cure. Before delivery is safe, doctors manage the condition with blood pressure medications like labetalol or nifedipine, magnesium sulfate to prevent seizures, and corticosteroids to speed up the baby's lung development if early delivery is necessary. You will need frequent monitoring with blood pressure checks, blood tests, and ultrasounds to assess baby's growth. Bed rest at home or hospitalization may be required for close observation. Women diagnosed after 37 weeks typically deliver immediately, while earlier cases are managed carefully with the goal of safely extending pregnancy.
How can I prevent preeclampsia?
Preeclampsia prevention starts with identifying risk factors through genetic testing like Factor V Leiden Mutation Analysis before pregnancy. Low-dose aspirin taken daily starting in the first trimester significantly reduces risk for high-risk women and should be discussed with your doctor. Maintaining adequate vitamin B2 levels through diet or supplementation may help, as deficiency is linked to increased risk. Regular prenatal care with blood pressure monitoring is essential for early detection. Managing pre-existing conditions like diabetes and high blood pressure before pregnancy, maintaining a healthy weight, and taking calcium supplements if your diet is low in calcium can all reduce your risk.
What can I do at home for preeclampsia?
If diagnosed with preeclampsia, you can support medical treatment at home by monitoring your blood pressure daily with a home device and reporting readings above 140/90 to your doctor immediately. Rest frequently on your left side to improve blood flow to the placenta, stay well-hydrated by drinking plenty of water, and follow a balanced diet rich in protein, fruits, and vegetables. Track your baby's movements and report decreased activity right away. Avoid salty foods that increase swelling, limit stressful activities, and attend all scheduled prenatal appointments. However, home care supplements but never replaces medical treatment, as preeclampsia is a serious condition requiring professional monitoring and intervention.
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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Factor V (Leiden) Mutation Analysis
Google reviews 505 reviews
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What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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