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Post-Traumatic Stress Disorder (PTSD) is a mental health condition that develops after experiencing or witnessing a traumatic event. It is caused by dysregulation of the stress response system, leading to elevated levels of stress hormones like norepinephrine and cortisol. The Catecholamines, Fractionated, Plasma (Dopamine) test is the most important test for monitoring how trauma affects stress hormone levels in the body.
PTSD is caused by exposure to traumatic events that overwhelm the brain's ability to process and cope with extreme stress. Traumatic experiences like combat, sexual assault, serious accidents, natural disasters, or witnessing violence trigger dysregulation in the stress response system, particularly the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system. This dysregulation leads to persistent elevation of stress hormones like norepinephrine and cortisol, which keeps the body in a constant state of fight-or-flight readiness even when no threat is present.
The Catecholamines, Fractionated, Plasma (Dopamine) test is the most important blood test for PTSD because it measures stress hormones including norepinephrine and dopamine that become dysregulated after trauma. PTSD causes elevated norepinephrine levels, which directly contribute to symptoms like hyperarousal, intrusive memories, nightmares, and heightened startle response. This test provides objective data about how trauma has affected your body's stress response system and can help healthcare providers monitor physiological changes alongside mental health treatment. While PTSD is diagnosed through clinical evaluation and psychological assessments, measuring these stress hormones offers valuable insight into the biological impact of trauma on your nervous system.
You should get tested if you have experienced a traumatic event and notice persistent symptoms lasting more than a month, including flashbacks, nightmares, severe anxiety, or uncontrollable thoughts about the trauma. Get tested if you find yourself avoiding places or people that remind you of the traumatic event, experiencing emotional numbness, or feeling constantly on edge with trouble sleeping and concentrating. Testing is especially important if you notice physical symptoms like rapid heartbeat, excessive sweating, or panic attacks that interfere with your daily life, work, or relationships, as these may indicate elevated stress hormone levels that can be monitored through blood work.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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