Pituitary Tumor Blood Test

What is Pituitary Tumors?

Pituitary tumors are abnormal growths in the pituitary gland, the master gland that controls hormone production throughout the body. They are caused by uncontrolled cell growth in the pituitary gland, which disrupts the production of adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH), and other critical hormones. The Cortisol, AM test is the most important test for detecting pituitary tumors that overproduce ACTH, leading to excess cortisol levels.

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What causes pituitary tumors?

Pituitary tumors are caused by uncontrolled cell growth in the pituitary gland, though the exact trigger for this abnormal growth is not fully understood. Most pituitary tumors are benign adenomas that develop spontaneously without a clear genetic or environmental cause. However, some tumors are linked to genetic conditions like multiple endocrine neoplasia type 1 (MEN1), which increases the risk of developing these growths. The tumors disrupt normal hormone production, causing the pituitary to either overproduce hormones like ACTH, growth hormone, or prolactin, or underproduce essential hormones, leading to various health complications.

What is the best test for pituitary tumors?

The Cortisol, AM test is the most important blood test for pituitary tumors because it detects elevated morning cortisol levels caused by ACTH-secreting tumors, which lead to Cushing disease. This test measures cortisol when it should naturally be at its highest, making abnormally high levels a strong indicator of pituitary tumor activity. The Tri-iodothyronine (T3) Total test is also essential because pituitary tumors can disrupt thyroid-stimulating hormone (TSH) production, resulting in abnormal T3 levels that signal thyroid hormone imbalances. While imaging tests like MRI are needed to visualize the tumor itself, these blood tests are critical for identifying the hormone imbalances that reveal how the tumor is affecting your body.

When should I get tested for pituitary tumors?

You should get tested if you experience unexplained weight gain, especially around your midsection and face, persistent fatigue, or noticeable changes in your physical appearance like a rounder face or increased facial hair. Other warning signs include severe headaches, vision problems like tunnel vision or double vision, irregular menstrual periods in women, or erectile dysfunction in men. If you notice easy bruising, purple stretch marks on your skin, or muscle weakness that makes it hard to climb stairs or stand up, these could indicate hormone imbalances from a pituitary tumor. Early testing helps identify the problem before complications develop.

What are the symptoms of pituitary tumors?
Pituitary tumor symptoms vary depending on which hormones are affected and whether the tumor is pressing on nearby structures. Hormone-related symptoms include unexplained weight changes, excessive thirst and urination, irregular periods or loss of menstruation, breast milk production when not pregnant or breastfeeding, erectile dysfunction, decreased libido, and abnormal body hair growth. Pressure symptoms from larger tumors include persistent headaches, vision problems (especially loss of peripheral vision), nausea, vomiting, dizziness, and unexplained fatigue. Some people also experience mood changes, depression, anxiety, or cognitive difficulties. Many pituitary tumors are discovered incidentally during brain scans performed for other reasons, as they can be asymptomatic in early stages.
Who is at risk for pituitary tumors?
Anyone can develop pituitary tumors, but they are most commonly diagnosed in adults between ages 30 and 60. People with a family history of multiple endocrine neoplasia type 1 (MEN1) or Carney complex have a higher genetic risk. Women are slightly more likely than men to develop certain types of pituitary tumors, particularly prolactinomas. While most pituitary tumors occur sporadically without identifiable risk factors, individuals with unexplained hormonal symptoms or a family history of endocrine disorders should discuss screening with their healthcare provider.
What happens if pituitary tumors are left untreated?
Untreated pituitary tumors can lead to serious complications depending on the type and size of the tumor. Hormone-secreting tumors can cause Cushing disease (from excess ACTH), acromegaly (from excess growth hormone), or hyperprolactinemia, leading to diabetes, high blood pressure, heart disease, osteoporosis, and infertility. Large tumors can press on the optic nerves, causing permanent vision loss if not addressed promptly. Tumors can also damage the remaining healthy pituitary tissue, resulting in hypopituitarism where the gland cannot produce enough hormones, leading to adrenal insufficiency, thyroid problems, and other life-threatening conditions. Early detection and treatment prevent these complications and preserve your quality of life.
Can pituitary tumors be diagnosed with a blood test?
Blood tests cannot diagnose the tumor itself, but they are essential for detecting the hormone imbalances that pituitary tumors cause. Tests like Cortisol, AM and T3 Total reveal whether your pituitary is overproducing or underproducing hormones, which strongly suggests tumor activity. These abnormal hormone levels guide doctors to order imaging studies like MRI to visualize the tumor. Blood tests are also used to monitor treatment effectiveness and track hormone levels over time. While you need an MRI for definitive diagnosis, blood work is the critical first step that alerts you and your doctor to investigate further.
How are pituitary tumors treated?
Pituitary tumor treatment depends on the tumor type, size, and hormone production. Many small, non-functioning tumors require only monitoring with periodic imaging and blood tests. Medication can effectively shrink prolactin-secreting tumors and control hormone levels in other types. Surgery to remove the tumor is often recommended for larger tumors or those causing significant symptoms, typically performed through the nose using minimally invasive techniques. Radiation therapy may be used if surgery is not possible or if the tumor returns. Hormone replacement therapy is often necessary if the tumor or its treatment affects the pituitary gland's ability to produce hormones. Your treatment plan is personalized based on your specific situation and symptoms.
How can I prevent pituitary tumors?
There is no known way to prevent pituitary tumors because most develop spontaneously without identifiable causes. However, if you have a family history of genetic conditions like multiple endocrine neoplasia type 1 (MEN1), genetic counseling and regular screening can help detect tumors early when they are easier to treat. Maintaining overall health through a balanced diet, regular exercise, and stress management supports your endocrine system function. The most important preventive measure is being aware of symptoms and getting tested promptly if you notice hormonal changes, unexplained weight gain, vision problems, or persistent headaches, as early detection significantly improves treatment outcomes.
What can I do at home for pituitary tumors?
While home remedies cannot treat pituitary tumors, certain lifestyle measures can help manage symptoms and support your overall health. Maintain a consistent sleep schedule to support natural hormone rhythms, especially cortisol production. Eat a balanced diet rich in whole foods, lean proteins, and vegetables to help stabilize blood sugar and weight, which can be affected by hormone imbalances. Practice stress reduction techniques like meditation, yoga, or deep breathing exercises, as stress can worsen hormonal symptoms. Keep a symptom diary tracking headaches, vision changes, energy levels, and other concerns to share with your healthcare provider. Stay hydrated and avoid excessive caffeine or alcohol, which can affect hormone levels and exacerbate symptoms.
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Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
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  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

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Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.

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* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

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