Pituitary Dysfunction Blood Test

What is Pituitary Dysfunction?

Pituitary dysfunction occurs when the pituitary gland at the base of the brain fails to produce the correct amounts of hormones that regulate other glands throughout the body. It is caused by tumors, injury, inflammation, or genetic defects affecting the pituitary gland's ability to produce Thyroid Stimulating Hormone (TSH), growth hormone, and other critical hormones. The Tri-iodothyronine Free (FT3) test is the most important test for diagnosis because abnormal free T3 levels indicate the pituitary gland is not properly regulating thyroid hormone production.

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What causes pituitary dysfunction?

Pituitary dysfunction is caused by pituitary tumors (adenomas), traumatic brain injury, infections like meningitis, surgical damage, radiation therapy to the brain, or genetic conditions affecting pituitary development. Pituitary tumors are the most common cause, which can press on healthy pituitary tissue and disrupt hormone production. Other causes include Sheehan syndrome (severe blood loss during childbirth), autoimmune inflammation, or stroke affecting blood flow to the pituitary gland.

What is the best test for pituitary dysfunction?

The Tri-iodothyronine Free (FT3) test is the most important test for pituitary dysfunction because it measures active thyroid hormone levels controlled by pituitary-produced Thyroid Stimulating Hormone (TSH). When the pituitary gland malfunctions, it cannot properly regulate TSH production, leading to abnormal free T3 levels that reveal pituitary problems. This test is essential because the pituitary controls multiple hormone systems through the thyroid, and abnormal T3 levels often provide the first clue of pituitary malfunction. Additional hormone tests like cortisol, growth hormone, and prolactin may be ordered to confirm the diagnosis and determine which pituitary hormones are affected.

When should I get tested for pituitary dysfunction?

You should get tested if you experience unexplained fatigue, sudden weight changes, irregular periods or sexual dysfunction, persistent headaches with vision problems, or symptoms of thyroid problems like heat or cold intolerance. Get tested immediately if you develop sudden severe headaches, vision loss, confusion, or extreme weakness, as these may indicate a pituitary emergency. Testing is also important if you have a history of brain injury, radiation therapy, or a known pituitary tumor that needs monitoring.

What are the symptoms of pituitary dysfunction?
Symptoms of pituitary dysfunction vary depending on which hormones are affected but commonly include chronic fatigue, unexplained weight gain or loss, low blood pressure, irregular or absent menstrual periods, erectile dysfunction, decreased sex drive, sensitivity to cold or heat, excessive thirst and urination, headaches, and vision problems. You might also experience muscle weakness, depression, dry skin, constipation, or difficulty concentrating. Some people notice breast milk production when not breastfeeding or growth changes in hands, feet, or facial features.
Who is at risk for pituitary dysfunction?
People at highest risk include those with pituitary tumors or brain tumors near the pituitary gland, individuals who have undergone brain surgery or radiation therapy, and those with traumatic brain injuries. Women who experienced severe bleeding during childbirth, people with autoimmune diseases, and individuals with genetic conditions like multiple endocrine neoplasia are also at increased risk. The condition can affect anyone at any age, though certain types of pituitary problems are more common in specific age groups.
What happens if pituitary dysfunction is left untreated?
Untreated pituitary dysfunction leads to severe hormone imbalances that can cause life-threatening complications like adrenal crisis (dangerously low cortisol), severe hypoglycemia, heart problems, osteoporosis, and infertility. Long-term effects include persistent fatigue, diabetes insipidus with dehydration, vision loss from tumor growth pressing on optic nerves, and increased risk of cardiovascular disease. In children, untreated pituitary dysfunction causes growth failure and delayed puberty. Early diagnosis and treatment prevent these complications and restore normal hormone balance.
Can pituitary dysfunction be diagnosed with a blood test?
Yes, pituitary dysfunction is primarily diagnosed with blood tests that measure hormone levels controlled by the pituitary gland. Blood tests for free T3, TSH, cortisol, prolactin, growth hormone, and sex hormones reveal whether the pituitary is producing appropriate amounts of regulating hormones. Abnormal results indicate pituitary malfunction and help determine which specific hormones are affected. Your doctor may also order imaging tests like MRI to visualize the pituitary gland and identify tumors or structural problems causing the dysfunction.
How is pituitary dysfunction treated?
Treatment depends on the underlying cause and includes hormone replacement therapy to restore deficient hormones, medications to shrink pituitary tumors or block excess hormone production, and surgery to remove tumors pressing on the pituitary gland. Hormone replacement typically involves thyroid hormone, cortisol, sex hormones, or growth hormone given as daily medications. Some pituitary tumors respond well to dopamine agonist medications that shrink the tumor without surgery. Radiation therapy may be used after surgery or when surgery is not possible. Most people with pituitary dysfunction require lifelong hormone replacement and regular monitoring.
How can I prevent pituitary dysfunction?
Most cases of pituitary dysfunction cannot be prevented because they result from tumors or unpredictable injuries, but you can reduce risk by wearing protective headgear during contact sports and activities with head injury risk, seeking immediate medical care after head trauma, and managing autoimmune conditions that may affect the pituitary. Regular health checkups help detect pituitary problems early when treatment is most effective. If you have a family history of pituitary tumors or genetic endocrine conditions, genetic counseling and regular screening may identify problems before symptoms develop.
What can I do at home for pituitary dysfunction?
While pituitary dysfunction requires medical treatment, you can support your health by taking hormone replacement medications exactly as prescribed, eating a balanced diet with adequate protein and nutrients, managing stress through relaxation techniques, getting regular gentle exercise as tolerated, and maintaining consistent sleep schedules. Keep detailed records of symptoms and medication responses to share with your doctor. Stay hydrated, avoid extreme temperature exposure if you have thyroid hormone imbalances, and wear a medical alert bracelet indicating your condition. Never stop or adjust hormone medications without consulting your healthcare provider.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Testosterone 375 ng/dL
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Normal Optimal 400 - 1000 High
375 ng/dL

What this means

Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

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* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

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Tri-iodothyronine Free (FT3)
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Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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