Sample results
A pituitary adenoma is a benign tumor that grows in the pituitary gland at the base of the brain. These tumors can overproduce hormones like ACTH (adrenocorticotropic hormone), which stimulates excessive cortisol production and causes Cushing's disease. The Cortisol, Total test is the most important test for detecting hormone overproduction from pituitary adenomas.
Pituitary adenomas are caused by abnormal cell growth in the pituitary gland, though the exact trigger remains unclear. Most cases develop spontaneously without a clear genetic link, but some are associated with inherited conditions like Multiple Endocrine Neoplasia type 1 (MEN1). These benign tumors can remain non-functioning or become functioning tumors that overproduce hormones like ACTH, prolactin, growth hormone, or thyroid-stimulating hormone, leading to various hormonal imbalances throughout the body.
The Cortisol, Total test is the most important blood test for pituitary adenomas because it detects elevated cortisol levels caused by ACTH-secreting tumors. When pituitary adenomas overproduce ACTH, they stimulate the adrenal glands to release excess cortisol, resulting in Cushing's disease. This test helps determine whether your adenoma is functioning and causing hormonal dysfunction. Additional hormone tests may include prolactin, growth hormone, IGF-1, and thyroid function tests depending on which hormones your tumor affects, but cortisol testing is essential for detecting one of the most common and serious complications.
You should get tested if you experience unexplained weight gain (especially around your midsection and face), persistent high blood pressure, unusual fatigue or muscle weakness, mood changes or depression, or changes in your appearance like facial rounding or a buffalo hump on your upper back. Women should get tested if they have irregular periods or unexpected milk production, while men should test if they experience decreased libido or erectile dysfunction. Early detection through blood testing helps identify hormone imbalances before they cause serious complications.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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Sample results
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