Peritonitis Blood Test

What is Peritonitis?

Peritonitis is a serious inflammation of the peritoneum, the thin tissue lining the abdominal cavity. It is caused by bacterial infection from conditions like appendicitis, bowel perforation, or contamination during peritoneal dialysis. The CA-125 test is the most important blood marker for monitoring peritoneal inflammation and treatment response.

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What causes peritonitis?

Peritonitis is caused by bacterial infection that contaminates the peritoneal cavity. The most common bacteria include Escherichia coli, Streptococcus species, and Staphylococcus aureus, which can enter through a ruptured appendix, perforated bowel, abdominal trauma, or complications from peritoneal dialysis. In some cases, fungal infections or chemical irritation from digestive juices can also trigger peritonitis, though bacterial infections remain the primary cause.

What is the best test for peritonitis?

The CA-125 test is the most important blood marker for monitoring peritonitis because it detects elevated levels caused by inflammation of the peritoneal tissue. While peritonitis is primarily diagnosed through clinical examination, imaging, and peritoneal fluid analysis, the CA-125 blood test provides valuable information about the severity of peritoneal inflammation and helps track your response to treatment. Healthcare providers use this marker alongside complete blood count (CBC) and inflammatory markers like C-reactive protein to get a comprehensive picture of the infection and inflammation levels in your body.

When should I get tested for peritonitis?

You should get tested immediately if you experience sudden severe abdominal pain that worsens with movement or touch, fever, nausea, vomiting, or abdominal swelling and tenderness. People on peritoneal dialysis should seek testing if they notice cloudy dialysis fluid, which is a key warning sign of infection. Anyone with recent abdominal surgery, bowel disease, or abdominal trauma who develops these symptoms needs urgent evaluation, as peritonitis is a medical emergency requiring immediate treatment.

What are the symptoms of peritonitis?
Peritonitis causes severe abdominal pain that typically starts suddenly and gets worse with movement or when the abdomen is touched. You might experience fever and chills, nausea and vomiting, loss of appetite, abdominal swelling and bloating, and an inability to pass gas or have bowel movements. The abdomen often becomes rigid and board-like to the touch, and you may feel extremely fatigued or develop a rapid heartbeat as your body fights the infection.
Who is at risk for peritonitis?
People undergoing peritoneal dialysis have the highest risk due to repeated access to the peritoneal cavity. Those with gastrointestinal conditions like appendicitis, diverticulitis, Crohn disease, or peptic ulcers are at increased risk if these conditions lead to bowel perforation. Recent abdominal surgery, abdominal trauma, liver cirrhosis with ascites, and conditions requiring feeding tubes also increase your risk of developing peritonitis.
What happens if peritonitis is left untreated?
Untreated peritonitis can rapidly progress to sepsis, a life-threatening condition where infection spreads throughout your bloodstream causing organ failure. The infection can create abscesses in the abdominal cavity, lead to septic shock with dangerously low blood pressure, and cause multiple organ failure affecting your kidneys, lungs, and heart. Without immediate treatment, peritonitis has a high mortality rate, making it one of the most serious abdominal emergencies requiring urgent medical intervention.
Can peritonitis be diagnosed with a blood test?
Blood tests alone cannot definitively diagnose peritonitis, but they play an essential supporting role in evaluation and monitoring. The CA-125 test can detect elevated inflammation markers in the peritoneum, while a complete blood count reveals elevated white blood cells indicating infection. Blood cultures can identify bacteria in your bloodstream, and inflammatory markers like C-reactive protein help assess severity. The primary diagnosis requires clinical examination, imaging studies like CT scans, and analysis of peritoneal fluid obtained through paracentesis.
How is peritonitis treated?
Peritonitis requires immediate hospitalization with intravenous antibiotics to fight the bacterial infection. Treatment typically includes broad-spectrum antibiotics initially, then specific antibiotics once the causative bacteria are identified through cultures. Many cases require emergency surgery to remove infected tissue, repair perforations, or drain abscesses. You will receive intravenous fluids, pain management, and possibly nutritional support, with treatment continuing until the infection is fully cleared and inflammation resolves.
How can I prevent peritonitis?
If you are on peritoneal dialysis, strict adherence to sterile technique when handling your catheter and equipment is crucial. Wash your hands thoroughly before and after dialysis exchanges, keep the catheter site clean and dry, and inspect dialysis fluid for cloudiness daily. For general prevention, seek prompt treatment for abdominal pain or digestive symptoms to prevent complications like appendix or bowel perforation. Maintain good hygiene, avoid abdominal trauma, and follow all post-surgical care instructions carefully if you have had abdominal surgery.
What can I do at home for peritonitis?
Peritonitis is a medical emergency that cannot be safely treated at home and requires immediate hospital care. While recovering after hospital treatment, you should rest completely, take all prescribed antibiotics exactly as directed, and avoid solid foods until your doctor approves. Stay well-hydrated with clear liquids initially, monitor your temperature regularly, and watch for any return of symptoms like abdominal pain or fever. Follow all wound care instructions carefully if you had surgery, and attend all follow-up appointments to ensure the infection has completely resolved.
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In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

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Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
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During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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CA-125 (Ovarian Cancer Test)
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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