Pantothenic Acid Deficiency Blood Test

What is Pantothenic Acid Deficiency?

Pantothenic acid deficiency is a rare nutritional condition caused by insufficient Vitamin B5 in the body. It is caused by inadequate dietary intake of pantothenic acid or malabsorption conditions that prevent proper vitamin absorption. The Vitamin B5 (Pantothenic Acid) blood test is the most important test for diagnosis because it directly measures circulating levels of this essential vitamin.

RECOMMENDED TEST Vitamin B5 (Pantothenic Acid)
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What causes pantothenic acid deficiency?

Pantothenic acid deficiency is caused by inadequate dietary intake of Vitamin B5, malabsorption disorders that prevent proper nutrient absorption, or certain medications that interfere with vitamin metabolism. Because pantothenic acid is widely available in foods like meat, vegetables, eggs, and whole grains, true deficiency is extremely rare in developed countries. However, people with severe malnutrition, chronic alcoholism, or inflammatory bowel diseases may be at higher risk for developing insufficient B5 levels.

What is the best test for pantothenic acid deficiency?

The Vitamin B5 (Pantothenic Acid) blood test is the most important test for pantothenic acid deficiency because it directly measures the concentration of this vitamin in your bloodstream. This test provides definitive confirmation of low B5 levels and helps distinguish pantothenic acid deficiency from other conditions with similar symptoms. By measuring actual vitamin levels rather than indirect markers, this test offers the most accurate assessment of your Vitamin B5 status and guides appropriate supplementation or dietary interventions to restore healthy levels.

When should I get tested for pantothenic acid deficiency?

You should get tested if you experience persistent fatigue, unexplained irritability, numbness or tingling in your hands and feet, frequent digestive problems like vomiting or abdominal cramps, or chronic sleep disturbances that don't improve with rest. Testing is especially important if you have malabsorption conditions, follow a highly restricted diet, or have symptoms that haven't responded to other treatments. Early detection through blood testing allows you to address the deficiency before it leads to more serious complications.

What are the symptoms of pantothenic acid deficiency?
Symptoms of pantothenic acid deficiency include persistent fatigue and weakness, irritability and mood changes, numbness or burning sensations in the hands and feet, digestive issues like nausea, vomiting, and abdominal cramps, difficulty sleeping or insomnia, headaches, and muscle cramps. Because these symptoms are nonspecific and overlap with many other conditions, blood testing is essential for accurate diagnosis. Some people may also experience decreased immune function and slower wound healing when B5 levels are severely depleted.
Who is at risk for pantothenic acid deficiency?
People at highest risk for pantothenic acid deficiency include those with severe malnutrition or eating disorders, individuals with chronic alcoholism, people with malabsorption conditions like Crohn's disease or celiac disease, and those following extremely restrictive diets. Individuals taking certain medications that interfere with vitamin absorption and people with genetic disorders affecting vitamin metabolism may also be at increased risk. However, because Vitamin B5 is abundant in most foods, deficiency remains extremely uncommon in people with access to a varied diet.
What happens if pantothenic acid deficiency is left untreated?
Untreated pantothenic acid deficiency can lead to worsening neurological symptoms including severe numbness, burning sensations, and potential nerve damage. The condition may progress to more serious complications like adrenal insufficiency, increased susceptibility to infections due to impaired immune function, chronic digestive problems, and persistent sleep disorders that affect overall quality of life. Early diagnosis through blood testing and appropriate treatment with supplementation or dietary changes can prevent these complications and restore normal vitamin levels before permanent damage occurs.
Can pantothenic acid deficiency be diagnosed with a blood test?
Yes, pantothenic acid deficiency can be definitively diagnosed with a blood test that measures Vitamin B5 levels in your bloodstream. The Vitamin B5 (Pantothenic Acid) blood test directly quantifies the amount of this vitamin circulating in your blood, providing clear evidence of deficiency when levels fall below normal ranges. This test is the gold standard for diagnosis because it measures the actual vitamin rather than relying on indirect indicators, making it both accurate and reliable for confirming suspected deficiency.
How is pantothenic acid deficiency treated?
Pantothenic acid deficiency is treated primarily through Vitamin B5 supplementation, typically in doses ranging from 5 to 10 milligrams daily for mild deficiency or higher doses for more severe cases. Your healthcare provider will determine the appropriate dosage based on your blood test results and symptom severity. Treatment also includes dietary modifications to increase intake of B5-rich foods like meat, eggs, legumes, whole grains, and vegetables. Most people see improvement in symptoms within a few weeks of starting treatment, though neurological symptoms may take longer to resolve completely.
How can I prevent pantothenic acid deficiency?
You can prevent pantothenic acid deficiency by eating a balanced diet that includes a variety of B5-rich foods such as chicken, beef, eggs, whole grains, avocados, mushrooms, legumes, and dairy products. Most people who consume a varied diet naturally get adequate Vitamin B5 without supplementation. If you have malabsorption conditions or take medications that interfere with vitamin absorption, work with your healthcare provider to monitor your levels and consider supplementation if needed. Limiting alcohol consumption and addressing any underlying digestive disorders also helps maintain healthy B5 levels.
What natural remedies help with pantothenic acid deficiency?
The most effective natural remedy for pantothenic acid deficiency is increasing your dietary intake of foods naturally rich in Vitamin B5, including organ meats like liver, salmon, chicken breast, eggs, sunflower seeds, avocados, sweet potatoes, mushrooms, and legumes like lentils and chickpeas. Whole grains also provide significant amounts of pantothenic acid. While these foods can help maintain adequate levels, confirmed deficiency typically requires targeted supplementation under medical guidance to restore normal levels quickly. Improving overall gut health through probiotics and addressing any malabsorption issues can also enhance your body's ability to absorb and utilize Vitamin B5 from food sources.
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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Vitamin B5 (Pantothenic Acid)
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What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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