Ovarian Tumor Blood Test

What is Ovarian Tumors?

Ovarian tumors are abnormal growths that develop in or on the ovaries and can be benign or malignant. Many ovarian tumors produce excess estrogen and estradiol hormones that enter the bloodstream and stimulate further tumor growth. The Estrogens (Total), Serum test is the most important test for detecting hormonal complications from ovarian tumors.

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What causes ovarian tumors?

Ovarian tumors are caused by abnormal cell growth in or on the ovaries, which can develop from various cell types including epithelial cells, germ cells, or stromal cells. The exact cause varies depending on the tumor type, but many hormone-producing tumors develop from granulosa cells or theca cells that naturally produce estrogen and estradiol. Risk factors include genetic mutations (especially BRCA1 and BRCA2), family history of ovarian or breast cancer, age, endometriosis, and hormone replacement therapy.

What is the best test for ovarian tumors?

The Estrogens (Total), Serum test is the most important blood test for ovarian tumors because it detects elevated estrogen levels that indicate hormone-producing tumor activity. This test measures all forms of estrogen in your bloodstream, which can be significantly elevated when tumors actively secrete hormones. For comprehensive monitoring, the Estradiol, Ultrasensitive, LC/MS/MS test provides highly sensitive detection of estradiol, the most potent estrogen form, while the Estriol, LC/MS/MS, Serum test identifies elevated estriol levels that can signal estrogen-producing tumors in non-pregnant women. While imaging studies like ultrasound and CT scans diagnose the tumor itself, these blood tests are essential for assessing hormonal complications and monitoring treatment response.

When should I get tested for ovarian tumors?

You should get tested if you experience irregular or abnormal menstrual periods, persistent pelvic or abdominal pain, bloating that does not go away, feeling full quickly when eating, or unexplained breast tenderness. Women with a family history of ovarian or breast cancer, those with genetic mutations like BRCA1 or BRCA2, or anyone experiencing symptoms of excess estrogen such as mood changes or unexpected vaginal bleeding should also consider testing. Testing is particularly important if symptoms persist for more than two weeks or interfere with daily activities.

What are the symptoms of ovarian tumors?
Ovarian tumors often cause pelvic or abdominal pain, bloating, feeling full quickly after eating, and changes in bowel or bladder habits. Hormone-producing tumors create additional symptoms including irregular menstrual periods, abnormal vaginal bleeding, breast tenderness, and mood swings. Some women notice abdominal swelling, unexplained weight loss or gain, or pain during intercourse. Many ovarian tumors are asymptomatic in early stages, which is why awareness of subtle changes and regular monitoring is important, especially for women with risk factors.
Who is at risk for ovarian tumors?
Women with genetic mutations like BRCA1 or BRCA2 face significantly higher risk for ovarian tumors, as do those with a family history of ovarian, breast, or colorectal cancer. Risk increases with age, particularly after menopause, though hormone-producing tumors can occur at any age. Women with endometriosis, those who have never been pregnant, and those who used hormone replacement therapy long-term have elevated risk. Lynch syndrome (hereditary nonpolyposis colorectal cancer) and early menstruation or late menopause also increase the likelihood of developing ovarian tumors.
What happens if ovarian tumors are left untreated?
Untreated ovarian tumors can grow larger and potentially become cancerous if they are initially benign. Hormone-producing tumors continue secreting excess estrogen and other hormones, leading to persistent symptoms like irregular bleeding, mood disturbances, and potential endometrial hyperplasia or cancer from prolonged estrogen exposure. Malignant tumors can spread to other pelvic organs, the abdomen, and distant sites through metastasis. Large tumors may cause ovarian torsion, where the ovary twists and cuts off its blood supply, creating a medical emergency. Early detection through blood testing and imaging significantly improves treatment outcomes.
Can ovarian tumors be diagnosed with a blood test?
Blood tests alone cannot definitively diagnose ovarian tumors, but they play a crucial role in detecting hormone imbalances and monitoring tumor activity. The Estrogens (Total), Serum test, Estradiol, Ultrasensitive, LC/MS/MS test, and Estriol, LC/MS/MS, Serum test measure elevated hormone levels produced by many ovarian tumors. CA-125 is another blood marker sometimes used for monitoring ovarian cancer. Diagnosis requires imaging studies like ultrasound, CT scans, or MRI to visualize the tumor, and definitive diagnosis comes from tissue biopsy. Blood tests provide valuable information about hormonal complications and help track treatment effectiveness.
How is an ovarian tumor treated?
Treatment depends on whether the tumor is benign or malignant, its size, hormone production, and your age and fertility goals. Benign tumors may be monitored with regular imaging and blood tests if small and asymptomatic. Surgical removal through laparoscopy or laparotomy is common for larger tumors or those causing symptoms. Malignant tumors typically require surgery to remove the affected ovary and surrounding tissue, often followed by chemotherapy. Hormone-producing tumors may need medications to block estrogen effects alongside surgical treatment. Your healthcare provider creates a personalized treatment plan based on tumor characteristics and your individual circumstances.
How can I prevent ovarian tumors?
While you cannot completely prevent ovarian tumors, certain measures reduce risk. Using oral contraceptives for several years significantly lowers ovarian cancer risk. Pregnancy and breastfeeding provide protective effects against ovarian tumors. Women with BRCA mutations or strong family history may consider prophylactic surgery to remove ovaries after completing their families. Maintaining a healthy weight, eating a balanced diet rich in vegetables and fruits, and avoiding long-term hormone replacement therapy help reduce risk. Regular gynecological checkups and discussing family history with your doctor enable early detection when treatment is most effective.
What natural remedies help with ovarian tumor symptoms?
Natural approaches can help manage symptoms but should never replace medical treatment for ovarian tumors. Eating cruciferous vegetables like broccoli and cauliflower supports healthy estrogen metabolism. Green tea contains antioxidants that may help cellular health. Managing stress through yoga, meditation, or gentle exercise can alleviate mood symptoms from hormonal imbalances. Reducing alcohol and avoiding processed foods high in sugar helps maintain hormonal balance. Omega-3 fatty acids from fish or flax seeds have anti-inflammatory properties. Always consult your healthcare provider before starting any supplements or natural remedies, as some may interfere with medical treatments or affect hormone levels.
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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

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Estrogens (Total), Serum
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No extra fees paid at the lab

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