Orange Allergy Blood Test

What is Orange Allergy?

Orange allergy is a food allergy where the immune system mistakenly identifies proteins in oranges as harmful invaders. It is caused by an abnormal immune response to specific proteins found in orange fruit, triggering the production of IgG antibodies. The Food Specific IgG Allergy (Pediatric) Panel is the most important test for diagnosis because it measures orange-specific IgG antibodies that indicate immune system reactivity.

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What causes orange allergy?

Orange allergy is caused by an overactive immune response to specific proteins found in orange fruit, particularly proteins like profilin and lipid transfer proteins. When you eat oranges, your immune system mistakenly identifies these harmless proteins as dangerous invaders and releases IgG antibodies and histamine to fight them off. This immune reaction triggers the uncomfortable and sometimes dangerous symptoms associated with food allergies, ranging from mild skin irritation to severe digestive or respiratory problems.

What is the best test for orange allergy?

The Food Specific IgG Allergy (Pediatric) Panel is the most important test for orange allergy because it measures IgG antibodies specific to orange proteins in your blood. When your immune system reacts to oranges, it produces elevated levels of these antibodies, which this panel can detect and quantify. The test identifies whether your body has developed an immune response to oranges specifically, helping distinguish a true allergy from other food sensitivities or intolerances. This comprehensive panel tests for multiple food allergies simultaneously, making it especially valuable if you suspect reactions to other foods beyond oranges.

When should I get tested for orange allergy?

You should get tested if you develop skin rashes, hives, or itching after eating oranges or drinking orange juice. Testing is also important if you experience stomach cramps, nausea, diarrhea, or bloating within hours of consuming oranges. Get tested immediately if you notice more serious symptoms like difficulty breathing, throat tightness, or swelling of the lips, tongue, or face after orange exposure. If you have a family history of food allergies or have noticed a pattern of symptoms after eating citrus fruits, testing can provide clarity and help you manage your diet safely.

What are the symptoms of orange allergy?
Symptoms of orange allergy include skin reactions like hives, rashes, itching, or eczema flare-ups. Digestive symptoms include stomach cramps, nausea, vomiting, diarrhea, and bloating. Respiratory symptoms may include runny nose, sneezing, coughing, wheezing, or difficulty breathing. Some people experience swelling of the lips, tongue, throat, or face. In severe cases, orange allergy can trigger anaphylaxis, a life-threatening reaction causing rapid pulse, drop in blood pressure, dizziness, and loss of consciousness requiring immediate emergency treatment.
Who is at risk for orange allergy?
People with a family history of food allergies or other allergic conditions like asthma, eczema, or hay fever are at higher risk for developing orange allergy. Children are more likely to develop food allergies than adults, though orange allergy can develop at any age. Those with oral allergy syndrome or birch pollen allergy may experience cross-reactive symptoms when eating oranges due to similar protein structures. People with existing citrus allergies or sensitivities to other fruits are also at increased risk of reacting to oranges.
What happens if orange allergy is left untreated?
If orange allergy is left untreated and you continue eating oranges, you risk repeated allergic reactions that may worsen over time. Ongoing exposure can lead to chronic inflammation in the digestive tract, causing persistent stomach problems and nutrient absorption issues. Repeated skin reactions can cause lasting dermatitis or worsening eczema. Most seriously, continued exposure increases the risk of severe anaphylactic reactions, which can be life-threatening without immediate treatment. Identifying and avoiding oranges through proper testing prevents these complications and improves your quality of life.
Can orange allergy be diagnosed with a blood test?
Yes, orange allergy can be diagnosed with a blood test that measures IgG antibodies specific to orange proteins. The Food Specific IgG Allergy Panel detects whether your immune system has produced antibodies against oranges, indicating an allergic response. Blood tests are particularly useful because they are safe, do not require exposure to the allergen during testing, and can measure your immune response objectively. When combined with your symptom history and dietary patterns, blood test results help healthcare providers confirm the diagnosis and develop an appropriate management plan.
How is orange allergy treated?
Orange allergy is treated primarily through strict avoidance of oranges and orange-containing products, including orange juice, orange zest, orange flavoring, and foods with citric acid derived from oranges. Antihistamines can help manage mild allergic symptoms if accidental exposure occurs. For severe reactions, carrying an epinephrine auto-injector is essential for emergency treatment of anaphylaxis. Reading food labels carefully is critical since oranges appear in many processed foods, beverages, and cosmetics. Working with an allergist or dietitian helps ensure you avoid hidden sources while maintaining proper nutrition through alternative vitamin C sources.
How can I prevent orange allergy reactions?
Prevent orange allergy reactions by carefully reading all food and beverage labels, avoiding products containing orange juice, orange concentrate, orange oil, orange flavoring, or citrus extracts. Be cautious at restaurants and inform servers about your allergy since oranges are used in salad dressings, marinades, desserts, and cocktails. Avoid cosmetics, lotions, and cleaning products with orange fragrance or citrus oils. When trying new foods, check ingredient lists and consider cross-contamination risks in facilities that process citrus fruits. Educate family members and caregivers about your allergy to prevent accidental exposure.
What natural remedies help with orange allergy symptoms?
While strict avoidance is the only way to prevent orange allergy, natural remedies can help manage mild symptoms after accidental exposure. Quercetin, a natural antihistamine found in apples, onions, and green tea, may help reduce allergic responses. Probiotics support gut health and immune function, potentially reducing food sensitivity reactions over time. Vitamin C from non-citrus sources like strawberries, bell peppers, and broccoli maintains immune health without triggering symptoms. Aloe vera gel can soothe skin reactions, while ginger tea may ease digestive discomfort. Always consult your healthcare provider before using supplements, especially if you have severe allergies requiring epinephrine.
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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Food Specific IgG Allergy (Pediatric) Panel
Google reviews 505 reviews
$1,004 $783
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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