Question 1

What is Non-Hodgkin Lymphoma?

Accepted Answer

Non-Hodgkin Lymphoma is a cancer that originates in the lymphatic system, which is part of the body's immune system. It is caused by abnormal growth of lymphocytes (white blood cells) that multiply uncontrollably and accumulate in lymph nodes and other tissues. The Kappa/Lambda Light Chains, Free with Ratio and Reflex to Immunofixation is the most important blood test for monitoring this condition because it detects abnormal protein patterns produced by cancerous immune cells.

Question 2

What causes Non-Hodgkin Lymphoma?

Accepted Answer

Non-Hodgkin Lymphoma is caused by genetic mutations in lymphocytes (B cells or T cells) that lead to uncontrolled cell growth and accumulation in the lymph nodes, spleen, and other organs. Risk factors include infections like Epstein-Barr virus, Helicobacter pylori, hepatitis C, and HIV, as well as autoimmune diseases and exposure to certain chemicals or radiation. While the exact trigger for these mutations is often unknown, weakened immune systems and chronic inflammation significantly increase the risk of developing this blood cancer.

Question 3

What is the best test for Non-Hodgkin Lymphoma?

Accepted Answer

The Kappa/Lambda Light Chains, Free with Ratio and Reflex to Immunofixation is the most important blood test for monitoring Non-Hodgkin Lymphoma because it detects abnormal protein production by cancerous lymphocytes. This test measures free kappa and lambda light chains in your blood and calculates their ratio, which becomes abnormal when lymphoma affects your immune cells. While tissue biopsy remains essential for initial diagnosis, this blood test is crucial for tracking disease progression, evaluating treatment response, and detecting potential relapse. The immunofixation reflex helps identify specific abnormal proteins that may indicate active disease or complications.

Question 4

When should I get tested for Non-Hodgkin Lymphoma?

Accepted Answer

You should get tested if you notice persistent swollen lymph nodes in your neck, armpits, or groin that last more than two weeks, unexplained fever or night sweats, sudden weight loss without dieting, or extreme fatigue that interferes with daily activities. Testing is also important if you experience persistent abdominal pain or swelling, frequent infections, or if you have a weakened immune system due to HIV, organ transplant, or autoimmune conditions. Early detection through blood work can help your healthcare provider assess abnormal protein patterns and determine if further evaluation is needed.

Question 5

What are the symptoms of Non-Hodgkin Lymphoma?

Accepted Answer

Non-Hodgkin Lymphoma symptoms include painless swelling of lymph nodes in the neck, armpits, or groin, persistent fever without infection, drenching night sweats, and unexplained weight loss of more than 10 pounds. You might also experience extreme fatigue, persistent cough or chest pain, abdominal pain or swelling, and frequent infections. Some people notice skin rashes or itching, while others have difficulty breathing if lymph nodes in the chest are enlarged. Symptoms can develop gradually and may be mistaken for common illnesses, which is why persistent symptoms warrant medical evaluation and blood testing.

Question 6

Who is at risk for Non-Hodgkin Lymphoma?

Accepted Answer

People with weakened immune systems are at highest risk, including those with HIV/AIDS, organ transplant recipients taking immunosuppressive drugs, and individuals with autoimmune diseases like rheumatoid arthritis or lupus. The risk increases with age, particularly after 60, and men are slightly more likely to develop it than women. Exposure to certain chemicals like pesticides and herbicides, previous chemotherapy or radiation treatment, and chronic infections with Epstein-Barr virus, hepatitis C, or Helicobacter pylori also elevate risk. Having a family history of lymphoma may increase your susceptibility, though most cases occur in people with no family history.

Question 7

What happens if Non-Hodgkin Lymphoma is left untreated?

Accepted Answer

Untreated Non-Hodgkin Lymphoma can spread rapidly throughout the lymphatic system and into vital organs including the liver, lungs, bone marrow, and brain. This progression leads to severe complications like bone marrow failure causing life-threatening anemia and bleeding, frequent serious infections due to immune system collapse, and organ damage that can result in respiratory failure or liver dysfunction. The cancer can cause dangerous fluid accumulation around the lungs or heart, and compress vital structures leading to breathing difficulties or blood flow obstruction. Without treatment, Non-Hodgkin Lymphoma is fatal, but early detection through blood testing and prompt intervention significantly improve survival rates and quality of life.

Question 8

Can Non-Hodgkin Lymphoma be diagnosed with a blood test?

Accepted Answer

Blood tests alone cannot definitively diagnose Non-Hodgkin Lymphoma, but they play a crucial role in detection and monitoring. The Kappa/Lambda Light Chains test can reveal abnormal protein patterns that suggest lymphoma, while complete blood counts may show abnormal white blood cell levels. A definitive diagnosis requires a lymph node biopsy where tissue is examined under a microscope to identify cancerous cells. However, blood tests are essential for assessing disease impact, monitoring treatment effectiveness, and detecting potential relapse. They provide valuable information about protein abnormalities, organ function, and overall health status that guides your healthcare provider's diagnostic and treatment decisions.

Question 9

How is Non-Hodgkin Lymphoma treated?

Accepted Answer

Non-Hodgkin Lymphoma treatment depends on the specific type, stage, and how aggressive the cancer is. Most patients receive chemotherapy, often combined with immunotherapy drugs like rituximab that target cancer cells specifically. Radiation therapy may be used for localized disease, while advanced cases might require stem cell transplantation to rebuild the immune system after intensive chemotherapy. Newer targeted therapies and CAR T-cell therapy are revolutionary treatments for certain lymphoma types. Some slow-growing lymphomas may only need careful monitoring called watchful waiting, while aggressive forms require immediate intensive treatment. Your oncologist will create a personalized treatment plan based on your specific lymphoma subtype and overall health.

Question 10

How can I prevent Non-Hodgkin Lymphoma?

Accepted Answer

While you cannot completely prevent Non-Hodgkin Lymphoma, you can reduce your risk by maintaining a healthy immune system through proper nutrition, regular exercise, and adequate sleep. Protect yourself from infections by practicing safe sex to avoid HIV and hepatitis C, treating Helicobacter pylori infections promptly, and getting appropriate vaccinations. Minimize exposure to harmful chemicals like pesticides, herbicides, and industrial solvents by using protective equipment when necessary. If you have an autoimmune condition, work closely with your doctor to manage it effectively. Avoid unnecessary radiation exposure and maintain regular check-ups, especially if you have risk factors, so any abnormalities can be detected early through blood testing.

Question 11

What can I do at home to support lymphoma treatment?

Accepted Answer

Supporting your body during lymphoma treatment involves eating a nutrient-rich diet with plenty of fruits, vegetables, lean proteins, and whole grains to maintain strength and support immune function. Stay well-hydrated, get adequate rest, and engage in gentle exercise like walking when you feel able, as physical activity can reduce fatigue and improve mood. Practice good hygiene to prevent infections, avoid crowds during periods of low immune function, and manage stress through meditation, yoga, or counseling. Keep a symptom diary to track changes and communicate effectively with your healthcare team. While these measures support overall health, they complement rather than replace medical treatment, and regular blood monitoring remains essential to track your response to therapy.

Question 12

How’s this work?

Accepted Answer

Getting your blood test with us is easy, private & backed by the power of science.Long story short:
            
                In the test options, use the filters or search box to narrow your choices and find the test you want.
                If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
                Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
                If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
                When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
                Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
                You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
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Question 13

How do I know which test to get?

Accepted Answer

In the test options, find the test you want.
            If you’re not sure which test to get, we can lend a hand in finding the right option.
            Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

Question 14

When will my lab results be available?

Accepted Answer

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know.
            After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop!
            If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Question 15

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Accepted Answer

Absolutely! We totally understand that errors can happen. No worries, we're here to help you.
            Just reach out to us via text at 754-799-7833 or shoot us an email at
            support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update.
            Our awesome team will jump right in and make sure everything is sorted out and accurate for you.
            There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.
            Our lab requires an address to be listed to generate an order.

Question 16

Do you accept health insurance?

Accepted Answer

Only HSA & FSA is accepted.
            Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.
            This policy applies to all insurance companies, including federal health insurance programs like Medicare.
            If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Question 17

Can I cancel my order?

Accepted Answer

Yes.
            We get it – sometimes your needs change.
            As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.
            If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
            You can read more about our cancellation policy here.

Question 18

How can I find a lab location near me?

Accepted Answer

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached!
            You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).
            Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.
            If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Non-Hodgkin Lymphoma Blood Test

What is Non-Hodgkin Lymphoma?

What causes Non-Hodgkin Lymphoma?

What is the best test for Non-Hodgkin Lymphoma?

When should I get tested for Non-Hodgkin Lymphoma?

References

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