Neuropathy Blood Test

What is Neuropathy?

Neuropathy is nerve damage that causes tingling, numbness, weakness, and pain in the hands and feet. It is caused by vitamin B12 deficiency, folate deficiency, diabetes, autoimmune disorders, and other metabolic conditions. The Vitamin B12 test is the most important test for neuropathy diagnosis because B12 deficiency is one of the most common and treatable causes of nerve damage.

RECOMMENDED TEST Vitamin B12
What's included
Fast & easy, results by email & SMS
No extra fees paid at the lab
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
Why Private MD Labs?
90-day money-back guarantee Lab order in minutes Save a trip to the doctor Low prices since 2005 Labs within 2 miles

What causes neuropathy?

Neuropathy is caused by vitamin B12 deficiency, folate deficiency, diabetes, autoimmune disorders, infections, toxins, and certain medications. The most common nutritional cause is vitamin B12 deficiency, which damages the protective myelin sheath around nerves. Diabetes is the leading metabolic cause, with high blood sugar levels gradually damaging small blood vessels that supply nerves. Other causes include chemotherapy drugs, alcohol abuse, kidney disease, thyroid disorders, and inherited genetic conditions that affect nerve function.

What is the best test for neuropathy?

The Vitamin B12 test is the most important blood test for neuropathy because B12 deficiency is one of the most common and reversible causes of nerve damage. This test measures serum B12 levels to identify deficiencies that cause tingling, numbness, and weakness in the hands and feet. The Vitamin B12 and Folates test is also essential because it evaluates both B12 and folate levels together, providing a comprehensive view of nutritional deficiencies affecting nerve health. Low levels of either vitamin can damage nerves and cause balance problems, making early detection critical for preventing permanent nerve damage.

When should I get tested for neuropathy?

You should get tested if you experience persistent tingling, numbness, or burning sensations in your hands or feet, especially if symptoms worsen at night. Testing is also important if you have unexplained weakness, difficulty walking, loss of balance, or sharp shooting pains in your limbs. People with diabetes, a history of vitamin deficiencies, heavy alcohol use, or those taking medications like chemotherapy should get tested promptly when nerve symptoms appear, as early detection can prevent permanent damage.

What are the symptoms of neuropathy?
Neuropathy symptoms include tingling or pins-and-needles sensations in the hands and feet, numbness that gradually spreads upward from the toes and fingers, sharp burning or stabbing pain, and extreme sensitivity to touch. You might also notice muscle weakness, difficulty picking up objects, loss of coordination and balance, and pain that worsens at night. Some people experience cramping, twitching, or a feeling like they are wearing invisible gloves or socks.
Who is at risk for neuropathy?
People with diabetes are at highest risk for neuropathy, especially those with poorly controlled blood sugar levels. Others at risk include people with vitamin B12 deficiency, vegetarians and vegans who do not supplement B12, heavy alcohol users, and individuals with autoimmune diseases like rheumatoid arthritis or lupus. Cancer patients receiving chemotherapy, people with kidney or liver disease, those taking certain medications, and anyone with a family history of inherited neuropathy also face increased risk.
What happens if neuropathy is left untreated?
Untreated neuropathy can lead to permanent nerve damage that causes chronic pain, complete loss of sensation in the feet and hands, and severe mobility problems. Loss of feeling in the feet increases the risk of unnoticed injuries, infections, and ulcers that can become serious and even require amputation in diabetic patients. Muscle weakness can progress to muscle wasting and permanent disability. Early treatment of underlying causes like vitamin deficiencies can reverse nerve damage, but delayed treatment often results in irreversible complications.
Can neuropathy be diagnosed with a blood test?
Neuropathy itself is diagnosed through clinical examination and nerve conduction studies, but blood tests are essential for identifying the underlying causes. Blood work can detect vitamin B12 deficiency, folate deficiency, diabetes, thyroid disorders, kidney problems, and autoimmune conditions that cause nerve damage. Finding and treating these underlying causes through blood testing can stop neuropathy progression and sometimes reverse nerve damage, making blood tests a critical part of the diagnostic process.
How is neuropathy treated?
Neuropathy treatment focuses on addressing the underlying cause and managing symptoms. Vitamin B12 or folate deficiencies are treated with supplements or injections. Diabetes management through blood sugar control is critical for diabetic neuropathy. Pain medications including gabapentin, pregabalin, or duloxetine help manage nerve pain. Physical therapy improves strength and balance, while topical treatments like capsaicin cream provide localized relief. Lifestyle changes including reducing alcohol consumption, eating a balanced diet, and regular exercise support nerve health and prevent further damage.
How can I prevent neuropathy?
Prevent neuropathy by managing diabetes carefully with regular blood sugar monitoring and maintaining healthy glucose levels. Eat a balanced diet rich in B vitamins, especially B12 from meat, fish, eggs, and fortified foods, or take supplements if you follow a vegetarian or vegan diet. Limit alcohol consumption, avoid smoking, exercise regularly to improve circulation, and protect your feet with proper footwear. Get regular check-ups to monitor vitamin levels, blood sugar, and other risk factors, and manage chronic conditions like autoimmune diseases with your healthcare provider.
What natural remedies help with neuropathy?
Natural remedies for neuropathy include taking B-complex vitamins, especially B12, B6, and folate, which support nerve health and repair. Alpha-lipoic acid supplements may reduce nerve pain and improve nerve function. Regular exercise improves blood flow to damaged nerves and helps manage underlying conditions like diabetes. Warm baths can temporarily relieve pain and tingling, while massage therapy improves circulation and reduces discomfort. Acupuncture provides pain relief for some people, and maintaining a healthy weight reduces pressure on peripheral nerves. Always consult with a healthcare provider before starting supplements, especially if you take medications.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Testosterone 375 ng/dL
Demo results
Normal Optimal 400 - 1000 High
375 ng/dL

What this means

Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

Us vs. Them

Not overhyped or overpriced. Just comprehensive blood testing made simple and for everyone.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

1,000,000+ blood tests later, here's what our customers say

Google reviews 505 reviews Next
Vitamin B12
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

Sample results

Sample image
For you & your coach Health insights Written in human language, backed by science.
Sample image
For you & your doc Classic lab report A familiar and comprehensive lab report.

Ask AI

Your 24/7 Lab Guide

Quick questions:

Which test is right for my symptoms?
What could be causing this?
When should I get tested?
A
Hi, I'm AI. I can help you find the right test, explain results, or prepare for your visit. What can I help with?
Just now
A
AI provides insights, not medical diagnoses.