Myopathies are diseases of the muscle tissue that cause muscle weakness, pain, and dysfunction due to improperly functioning muscle fibers. They are caused by autoimmune processes where the body produces antibodies that attack muscle components, genetic defects, metabolic disorders, or inflammatory conditions. The Cytosolic 5'-Nucleotidase 1A (cN-1A) Antibody test is the most important blood test for diagnosing autoimmune myopathies because it detects specific antibodies associated with muscle damage.
90-day money-back guarantee
Lab order in minutes
Save a trip to the doctor
Low prices since 2005
Labs within 2 miles
Myopathies are caused by autoimmune processes where the immune system produces antibodies that mistakenly attack muscle tissue, genetic mutations affecting muscle protein production, metabolic disorders that disrupt energy production in muscle cells, or inflammatory conditions. Autoimmune myopathies like inclusion body myositis and necrotizing myopathy involve specific antibodies such as cN-1A antibodies targeting muscle enzymes. Other causes include inherited conditions like muscular dystrophy, endocrine disorders affecting thyroid or cortisol levels, and toxic exposures to certain medications or substances that damage muscle fibers.
The Cytosolic 5'-Nucleotidase 1A (cN-1A) Antibody (IgG) test is the most important blood test for autoimmune myopathies because it detects specific antibodies that attack the cN-1A enzyme in muscle cells, helping identify the autoimmune cause of muscle damage. This specialized antibody test is particularly valuable for diagnosing inclusion body myositis and other autoimmune muscle diseases. Additional blood tests that support myopathy diagnosis include creatine kinase (CK) levels which measure muscle breakdown, aldolase levels indicating muscle inflammation, and other myositis-specific antibodies. The cN-1A antibody test is essential because a positive result directly guides treatment decisions toward immunosuppressive therapies and helps distinguish autoimmune myopathies from other muscle disorders.
You should get tested if you experience progressive muscle weakness that makes climbing stairs or lifting objects difficult, unexplained muscle pain or tenderness that persists for weeks, difficulty swallowing or frequent choking episodes, or muscle fatigue that worsens throughout the day. Testing is especially important if you notice weakness in your shoulders, hips, or thighs, have trouble rising from a chair without using your arms, or develop muscle weakness alongside skin rashes or joint pain. Early testing helps identify the specific type of myopathy and allows for prompt treatment to prevent further muscle damage and preserve function.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
Not overhyped or overpriced. Just comprehensive blood testing made simple and for everyone.
505 reviews
Sample results
Your 24/7 Lab Guide
Quick questions:
