Mitochondrial disorders are genetic conditions that impair the mitochondria's ability to produce cellular energy, affecting multiple organ systems including muscles, brain, and heart. These disorders are caused by mutations in mitochondrial DNA or nuclear DNA that controls mitochondrial function, leading to cellular energy depletion. The Coenzyme Q10 blood test is the most important test for assessing mitochondrial function because it measures this essential compound required for cellular energy production.
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Mitochondrial disorders are caused by genetic mutations in either mitochondrial DNA or nuclear DNA that controls mitochondrial function. These mutations can be inherited from your mother (mitochondrial DNA is passed down maternally) or occur spontaneously as new mutations. The mutations disrupt the mitochondria's ability to produce ATP, the energy currency of cells, leading to organ dysfunction in tissues with high energy demands like the brain, heart, muscles, and eyes.
The Coenzyme Q10 blood test is the most important blood test for mitochondrial disorders because it measures levels of this essential compound required for cellular energy production within mitochondria. Low CoQ10 levels indicate impaired mitochondrial function and can help guide supplementation therapy. While definitive diagnosis requires specialized genetic testing and sometimes muscle biopsies, the CoQ10 test provides valuable information about mitochondrial function and helps monitor treatment effectiveness. Testing CoQ10 levels is particularly useful because supplementation with this compound has shown benefits in managing symptoms for some patients with mitochondrial disorders.
You should get tested if you experience unexplained muscle weakness, exercise intolerance, or fatigue that doesn't improve with rest. Testing is also important if you have neurological symptoms like seizures, developmental delays, or vision problems combined with muscle issues. Consider testing if multiple family members have similar unexplained symptoms, or if you have organ dysfunction affecting the heart, liver, or kidneys without a clear cause. Early testing helps guide treatment decisions and supplementation strategies that may improve quality of life.
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What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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