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Meningococcal meningitis is a severe bacterial infection causing inflammation of the protective membranes covering the brain and spinal cord. It is caused by Neisseria meningitidis bacteria that invade the bloodstream and central nervous system. The Complement Component C4 test is the most important blood test for assessing immune response severity during active infection.
Meningococcal meningitis is caused by the bacteria Neisseria meningitidis, which spreads through respiratory droplets from coughing, sneezing, or close contact with infected individuals. The bacteria travel through the bloodstream and cross the blood-brain barrier to infect the meninges, the protective membranes surrounding the brain and spinal cord. This infection triggers a severe inflammatory response that can lead to brain damage, hearing loss, or death if not treated immediately with antibiotics.
The Complement Component C4 test is the most important blood test for meningococcal meningitis because it measures how actively your immune system is fighting the infection. During acute infection, the complement system becomes highly activated to attack the bacteria, which causes C4 levels to drop significantly. Low C4 levels indicate a severe, ongoing immune response and help doctors understand the infection severity and guide aggressive treatment decisions. While cerebrospinal fluid analysis remains the primary diagnostic method, complement testing provides crucial information about immune system function and potential complications.
You should get tested immediately if you experience sudden high fever combined with severe headache, stiff neck, sensitivity to light, or confusion. Other warning signs include a purple or red rash that does not fade when pressed, nausea with vomiting, difficulty staying awake, or seizures. Meningococcal meningitis is a medical emergency that progresses rapidly, sometimes within hours, so immediate medical attention and testing are critical if you have been exposed to someone with the infection or develop these symptoms.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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