Sample results
Longevity refers to the length of an individual's lifespan and their ability to maintain health as they age. It is influenced by genetic variations in genes like ApoE, which affects cholesterol metabolism, cardiovascular health, and cellular aging processes. The ApoE Genotype test is the most important genetic test for longevity assessment because it identifies inherited factors associated with extended lifespan.
Differences in longevity are caused by a combination of genetic variations, lifestyle factors, and environmental influences. Genetic factors account for approximately 20-30% of lifespan variation, with specific genes like ApoE, FOXO3, and CETP playing crucial roles in cellular aging, metabolism, and disease resistance. The remaining 70-80% is influenced by modifiable factors including diet, exercise, stress management, sleep quality, social connections, and exposure to environmental toxins throughout life.
The ApoE Genotype test is the most important genetic test for longevity assessment because it identifies which variant of the ApoE gene you carry, particularly the longevity-associated ε2 allele. This test analyzes how your body metabolizes cholesterol and fats, which directly impacts cardiovascular health and brain aging. People with the ε2 variant typically have lower cholesterol levels, reduced risk of Alzheimer's disease, and statistically longer lifespans compared to those with ε3 or ε4 variants. While genetic testing provides insights into inherited predispositions, it should be combined with lifestyle assessments and standard health markers like cholesterol panels, inflammation markers, and metabolic function tests for a comprehensive longevity evaluation.
You should get tested if you want to understand your genetic predisposition for healthy aging and make informed lifestyle decisions based on your unique biology. Testing is particularly valuable if you have a family history of early cardiovascular disease, Alzheimer's disease, or exceptional longevity, as genetic factors may play a significant role. Consider testing in your 30s or 40s when you can still implement preventive strategies, or at any age if you are developing a personalized health optimization plan with your healthcare provider.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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Sample results
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