Lithium toxicity is a dangerous medical condition where lithium levels in the blood become elevated to toxic concentrations. It is caused by excessive lithium intake, decreased kidney elimination of the drug, or medication interactions that affect lithium clearance. The Lithium blood test is the most important test for diagnosis because it directly measures lithium concentration and determines the severity of toxicity.
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Lithium toxicity is caused by excessive accumulation of lithium in the bloodstream, which happens when lithium intake exceeds the body's ability to eliminate it through the kidneys. Common triggers include taking too much lithium medication, dehydration that concentrates lithium levels, kidney problems that reduce lithium elimination, and interactions with medications like diuretics, NSAIDs, or ACE inhibitors that affect how the body processes lithium. Other factors include low-sodium diets, excessive sweating, vomiting, or diarrhea that lead to dehydration and concentrated lithium levels in the blood.
The Lithium blood test is the most important test for lithium toxicity because it directly measures the concentration of lithium in your bloodstream and determines whether levels have reached toxic ranges. This test is essential for confirming the diagnosis, as symptoms alone cannot accurately predict lithium levels. Normal therapeutic lithium levels range from 0.6 to 1.2 mEq/L, while levels above 1.5 mEq/L indicate toxicity, and levels above 2.0 mEq/L represent severe, life-threatening toxicity. The test provides immediate, objective evidence that guides emergency treatment decisions and helps healthcare providers determine the appropriate intervention, whether that's stopping lithium, providing intravenous fluids, or starting dialysis in severe cases.
You should get tested immediately if you take lithium medication and develop symptoms like severe tremors, confusion, slurred speech, extreme drowsiness, persistent vomiting or diarrhea, muscle weakness, or loss of coordination. Get tested urgently if you become dehydrated from illness, start new medications that interact with lithium, or experience changes in kidney function. Regular monitoring is also important even without symptoms if you take lithium long-term, typically every 3-6 months, or after any dose changes. If you suspect toxicity, this is a medical emergency requiring immediate blood testing and professional care.
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What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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