Late Stage HIV or AIDS Blood Test

What is Late stage HIV or AIDS?

Late-stage HIV infection and AIDS represent advanced stages of HIV disease where the immune system has become severely compromised. It is caused by the Human Immunodeficiency Virus (HIV-1 or HIV-2) that destroys CD4+ T cells, leaving the body unable to fight infections. The HIV 1/2 Antigen and Antibodies Fourth Generation test is the most important test for screening, though results require careful medical interpretation in advanced disease stages.

RECOMMENDED TEST HIV 1/2 Antigen and Antibodies, Fourth Generation
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What causes late stage HIV or AIDS?

Late stage HIV or AIDS is caused by the Human Immunodeficiency Virus (HIV-1 or HIV-2), which attacks and destroys CD4+ T cells that coordinate your immune system response. As the virus replicates over years without treatment, it progressively weakens your immune defenses until your body can no longer fight off infections and diseases. AIDS is diagnosed when your CD4 count drops below 200 cells per cubic millimeter or when you develop certain opportunistic infections that healthy immune systems normally prevent.

What is the best test for late stage HIV or AIDS?

The HIV 1/2 Antigen and Antibodies Fourth Generation test is the most important screening test for HIV because it detects both p24 antigens (viral proteins present early in infection) and antibodies your body produces against the virus. This dual detection makes it the most comprehensive screening available. However, in late-stage HIV or AIDS, your severely compromised immune system may not produce antibodies efficiently, so healthcare providers must interpret results carefully alongside your clinical symptoms and may order additional tests like viral load measurements or CD4 counts to assess disease progression.

When should I get tested for late stage HIV or AIDS?

You should get tested if you experience persistent fever, extreme unexplained fatigue, rapid weight loss, chronic diarrhea, persistent white spots in your mouth, recurring pneumonia, or unusual skin lesions. Anyone with known HIV exposure or previous positive HIV tests should maintain regular monitoring. Testing is especially critical if you have multiple opportunistic infections, night sweats lasting weeks, or swollen lymph nodes that do not resolve, as these may indicate advanced disease requiring immediate medical attention.

What are the symptoms of late stage HIV or AIDS?
Symptoms of late stage HIV or AIDS include severe weight loss, chronic diarrhea lasting more than a month, persistent fever or night sweats, extreme fatigue, and prolonged swelling of lymph nodes. You might notice recurring respiratory infections like pneumonia, white spots or unusual lesions in your mouth or on your tongue, skin rashes or bumps that do not heal, and memory problems or confusion. Opportunistic infections such as tuberculosis, toxoplasmosis, or certain cancers like Kaposi sarcoma become common as your immune system fails.
Who is at risk for late stage HIV or AIDS?
People at highest risk for progressing to late stage HIV or AIDS include those with untreated HIV infection, individuals who do not know their HIV status, and those who are not adhering to antiretroviral therapy. Risk increases significantly if you have inconsistent access to healthcare, untreated co-infections like hepatitis or tuberculosis, or conditions that further suppress immunity. Anyone diagnosed with HIV who delays treatment or stops medications is at serious risk of disease progression to AIDS within several years.
What happens if late stage HIV or AIDS is left untreated?
Untreated late stage HIV or AIDS leads to life-threatening opportunistic infections and cancers that a healthy immune system would normally prevent. Your body loses its ability to fight even minor infections, resulting in conditions like Pneumocystis pneumonia, cryptococcal meningitis, severe tuberculosis, and widespread fungal infections. Without antiretroviral treatment, most people with AIDS develop multiple organ failure and survive only 1-3 years after AIDS diagnosis. Early detection and immediate treatment with antiretroviral therapy can prevent these complications and allow people to live long, healthy lives.
Can late stage HIV or AIDS be diagnosed with a blood test?
Yes, late stage HIV or AIDS can be diagnosed with blood tests, though results require careful interpretation. The HIV 1/2 Antigen and Antibodies Fourth Generation test screens for the virus, while CD4 count tests measure immune system damage and viral load tests measure the amount of virus in your blood. AIDS is diagnosed when your CD4 count falls below 200 cells per cubic millimeter or when specific opportunistic infections are present. Because advanced HIV disease can impair antibody production, healthcare providers often use multiple test types together to assess your status accurately.
How is late stage HIV or AIDS treated?
Late stage HIV or AIDS is treated with combination antiretroviral therapy (ART), which involves taking multiple medications daily that suppress viral replication and allow your immune system to recover. Treatment also includes medications to prevent and treat opportunistic infections like Pneumocystis pneumonia, toxoplasmosis, and fungal infections. Your healthcare team will monitor your CD4 count and viral load regularly to ensure treatment effectiveness. With consistent ART adherence, even people with advanced HIV can achieve undetectable viral loads, rebuild their immune systems, and dramatically improve their life expectancy and quality of life.
How can I prevent progression to late stage HIV or AIDS?
You can prevent progression to late stage HIV or AIDS by getting tested regularly if you are at risk, starting antiretroviral therapy immediately after diagnosis, and taking your medications consistently every day as prescribed. Maintaining regular medical appointments for CD4 and viral load monitoring helps catch any treatment issues early. Avoiding other infections through vaccinations, practicing safe sex even when HIV-positive, not sharing needles, and maintaining overall health through good nutrition and avoiding tobacco and excessive alcohol all help prevent disease progression.
What can I do at home to support my health with late stage HIV or AIDS?
At home, focus on taking your antiretroviral medications exactly as prescribed without missing doses, as consistency is critical for treatment success. Eat a nutrient-rich diet with adequate protein to support your immune system, stay well-hydrated, and get sufficient sleep to help your body recover. Practice careful hygiene to avoid infections, including thorough handwashing and safe food preparation. Avoid contact with people who are sick, manage stress through relaxation techniques, and stay connected with your healthcare team. While these measures support treatment, they cannot replace antiretroviral therapy, which remains essential for survival.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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HIV 1/2 Antigen and Antibodies, Fourth Generation
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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