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Kidney failure is a serious medical condition where the kidneys lose their ability to filter waste products and excess fluids from the blood effectively. It is caused by various factors including diabetes, high blood pressure, infections, autoimmune diseases, and toxic substance exposure such as ethylene glycol from antifreeze. The Ethylene Glycol Urine Test is the most important specialized test for identifying toxic causes of kidney failure when standard kidney function tests show abnormal results.
Kidney failure is caused by conditions that damage the kidneys over time or suddenly overwhelm their filtering capacity. Diabetes and high blood pressure are the two leading causes, responsible for nearly two-thirds of all kidney failure cases. Other causes include infections, autoimmune diseases like lupus, genetic disorders such as polycystic kidney disease, prolonged use of certain medications, and exposure to toxic substances like ethylene glycol found in antifreeze. When any of these factors damage the nephrons (tiny filtering units in the kidneys), waste products and fluids accumulate in the blood, leading to kidney failure.
The Ethylene Glycol Urine Test is the most important specialized test for kidney failure when toxic exposure is suspected because it detects this poisonous substance that can cause severe kidney damage. While standard blood tests measuring creatinine and blood urea nitrogen (BUN) are essential for diagnosing kidney failure itself, the ethylene glycol test identifies a specific treatable cause that might otherwise be missed. This is particularly critical because ethylene glycol from antifreeze, coolants, or industrial chemicals creates toxic metabolites that destroy kidney tissue, and early detection allows for life-saving interventions to prevent irreversible damage. Your doctor will typically order basic kidney function tests first, then add specialized testing like the ethylene glycol urine test if your exposure history or symptoms suggest toxic causes.
You should get tested if you notice decreased urination, swelling in your legs or ankles, persistent fatigue, nausea, confusion, or shortness of breath, as these are common signs of kidney failure. People with diabetes, high blood pressure, heart disease, or a family history of kidney disease should get regular kidney function testing even without symptoms. Additionally, if you work with or have been exposed to industrial chemicals, antifreeze, or coolants, specialized testing for toxic substances like ethylene glycol is essential to catch kidney damage early. Early detection through blood work can prevent progression to complete kidney failure and the need for dialysis.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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