Kidney dysfunction refers to the reduced ability of the kidneys to filter waste products, regulate fluid balance, and maintain proper electrolyte levels in the body. It is caused by damage to the nephrons (kidney filtering units) from conditions like diabetes, high blood pressure, infections, or autoimmune diseases. The Protein Electrophoresis and Total Protein, Random Urine test is the most important test for detecting kidney dysfunction because it identifies protein loss in urine, a key early indicator of kidney damage.
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Kidney dysfunction is caused by damage to the nephrons, which are the tiny filtering units inside your kidneys. The most common culprits include diabetes (high blood sugar damages blood vessels in the kidneys), high blood pressure (puts excessive strain on kidney tissues), chronic urinary tract infections, autoimmune diseases like lupus, and prolonged use of certain medications like NSAIDs. Other causes include kidney stones, polycystic kidney disease, and reduced blood flow to the kidneys from heart disease or dehydration.
The Protein Electrophoresis and Total Protein, Random Urine test is the most important test for kidney dysfunction because it detects proteinuria (protein in urine), which is one of the earliest and most reliable signs of kidney damage. Healthy kidneys prevent protein from leaking into urine, so finding elevated levels indicates the filtering system is compromised. This test also identifies which specific proteins are being lost, helping doctors determine the type and severity of kidney damage. The Selenium, 24-Hour Urine test provides additional insight by measuring how well your kidneys regulate and excrete this essential trace mineral, with abnormal levels signaling impaired kidney function.
You should get tested if you notice foamy or bubbly urine (a sign of protein), swelling in your ankles, feet, or hands, frequent urination especially at night, fatigue that won't go away, or changes in urine color or amount. People with diabetes, high blood pressure, heart disease, or a family history of kidney disease should get tested regularly even without symptoms, as kidney dysfunction often develops silently over years. If you take medications long-term like ibuprofen or have had repeated urinary tract infections, testing can catch problems early when treatment is most effective.
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What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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