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Iodine deficiency is a nutritional condition that occurs when the body does not get enough iodine, an essential mineral needed for thyroid hormone production. It is caused by insufficient dietary intake of iodine from foods like iodized salt, seafood, and dairy products. The Thyroglobulin LC/MS/MS test is the most important test for assessing the impact of iodine deficiency on thyroid function.
Iodine deficiency is caused by insufficient dietary intake of iodine, an essential mineral that the body cannot produce on its own. The primary dietary sources of iodine include iodized salt, seafood, seaweed, dairy products, and eggs. People who avoid these foods, live in regions with iodine-poor soil, follow strict vegan diets without iodized salt, or have increased iodine needs during pregnancy and breastfeeding are at higher risk of developing deficiency.
The Thyroglobulin LC/MS/MS test is the most important blood test for assessing iodine deficiency because it measures thyroglobulin levels, a protein that requires iodine for production in the thyroid gland. When iodine levels are inadequate, thyroglobulin production decreases, making this test valuable for evaluating how iodine deficiency affects thyroid function. This advanced test uses LC/MS/MS technology for precise measurement and helps healthcare providers monitor the impact of low iodine on thyroid protein synthesis. While urine iodine tests directly measure iodine excretion, the thyroglobulin blood test provides insight into the functional consequences of deficiency on your thyroid health.
You should get tested if you experience symptoms of thyroid dysfunction such as fatigue, weight gain, feeling cold, dry skin, hair loss, or notice swelling in your neck (goiter). Pregnant women, people who avoid iodized salt and seafood, those following strict vegan diets, and individuals living in regions with iodine-depleted soil should consider testing. Testing is also important if you have unexplained difficulty concentrating, muscle weakness, or irregular menstrual periods, as these can indicate thyroid problems related to iodine deficiency.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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