Impaired Cognitive Function Blood Test

What is Impaired Cognitive Function?

Impaired cognitive function is a decline in mental abilities including memory, thinking, concentration, and decision-making that interferes with daily activities. It is caused by genetic risk factors such as the ApoE ε4 allele, nutritional deficiencies, thyroid disorders, vascular disease, and neurodegenerative processes. The ApoE Genotype test is the most important genetic test for assessing inherited risk factors for cognitive decline.

RECOMMENDED TEST ApoE Genotype(11) (QSC)
Google reviews 505 reviews
$1,479 $1,154
What's included
Fast & easy, results by email & SMS
No extra fees paid at the lab
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
Why Private MD Labs?
90-day money-back guarantee Lab order in minutes Save a trip to the doctor Low prices since 2005 Labs within 2 miles

What causes impaired cognitive function?

Impaired cognitive function is caused by multiple factors including genetic predisposition, vascular disease, nutritional deficiencies, thyroid disorders, chronic inflammation, and neurodegenerative processes. The ApoE ε4 allele is a significant genetic risk factor that affects brain cholesterol metabolism and increases susceptibility to cognitive decline. Other contributing factors include vitamin B12 deficiency, hypothyroidism, diabetes, high blood pressure, and conditions that reduce blood flow to the brain.

What is the best test for impaired cognitive function?

The ApoE Genotype test is the most important genetic test for impaired cognitive function because it identifies variants of the ApoE gene, particularly the ε4 allele, which significantly increases risk for cognitive decline independent of Alzheimer's disease. This test reveals your inherited risk profile and helps guide personalized prevention strategies. Additional supportive tests may include thyroid function panels to rule out hypothyroidism, vitamin B12 and folate levels to identify nutritional deficiencies, and comprehensive metabolic panels to assess overall health factors that contribute to cognitive health.

When should I get tested for impaired cognitive function?

You should get tested if you notice increasing forgetfulness, difficulty concentrating or making decisions, trouble finding words during conversations, getting lost in familiar places, or if you have a family history of dementia or cognitive decline. Testing is especially important if you are over 50, have cardiovascular risk factors like high blood pressure or diabetes, or are concerned about your genetic risk. Early identification of risk factors through genetic testing like ApoE genotyping allows you to implement lifestyle modifications and preventive strategies before significant cognitive decline occurs.

What are the symptoms of impaired cognitive function?
Symptoms of impaired cognitive function include memory loss that disrupts daily life, difficulty planning or solving problems, confusion with time or place, trouble completing familiar tasks, problems with words in speaking or writing, misplacing things and losing the ability to retrace steps, decreased or poor judgment, withdrawal from work or social activities, and changes in mood or personality. Early signs often involve forgetting recently learned information, important dates, or asking for the same information repeatedly.
Who is at risk for impaired cognitive function?
People at higher risk for impaired cognitive function include those over age 65, individuals with the ApoE ε4 genetic variant, people with cardiovascular disease or diabetes, those with a family history of dementia, individuals with chronic high blood pressure or high cholesterol, people who have experienced traumatic brain injury, those with low educational attainment or limited mental stimulation, individuals with depression or chronic stress, smokers, and people with poor sleep quality or sleep disorders. Lifestyle factors such as physical inactivity, poor diet, and social isolation also increase risk.
What happens if impaired cognitive function is left untreated?
If impaired cognitive function is left untreated, it can progress to more severe cognitive decline and dementia, significantly impacting quality of life and independence. Individuals may lose the ability to perform daily activities, require full-time care, experience personality changes and behavioral problems, become vulnerable to financial exploitation, and face increased risk of accidents and injuries. Early intervention can slow progression, address treatable underlying causes like thyroid disorders or vitamin deficiencies, and allow individuals to participate in care planning while they still have decision-making capacity.
Can impaired cognitive function be diagnosed with a blood test?
Impaired cognitive function cannot be directly diagnosed with blood tests alone, as diagnosis requires comprehensive neuropsychological assessments and clinical evaluation. However, blood tests play a crucial supporting role by identifying genetic risk factors through ApoE genotyping, ruling out treatable underlying causes such as thyroid disorders, vitamin B12 deficiency, diabetes, or infections, and assessing vascular risk factors that contribute to cognitive decline. Blood testing provides valuable information for risk assessment, prevention strategies, and identifying reversible causes of cognitive symptoms.
How is impaired cognitive function treated?
Treatment for impaired cognitive function focuses on addressing underlying causes, managing symptoms, and slowing progression through medications like cholinesterase inhibitors and memantine for Alzheimer-related decline, treating contributing conditions such as thyroid disorders or vitamin deficiencies, managing cardiovascular risk factors with blood pressure and cholesterol medications, implementing cognitive rehabilitation and memory strategies, and making lifestyle modifications including regular exercise, heart-healthy diet, mental stimulation, social engagement, and quality sleep. Treatment plans are individualized based on the underlying cause and severity of cognitive impairment.
How can I prevent impaired cognitive function?
You can reduce your risk of impaired cognitive function by engaging in regular physical exercise at least 150 minutes per week, following a Mediterranean or MIND diet rich in vegetables, fish, and healthy fats, maintaining social connections and participating in mentally stimulating activities, controlling cardiovascular risk factors like blood pressure, cholesterol, and diabetes, getting 7-9 hours of quality sleep nightly, managing stress through relaxation techniques, avoiding smoking and excessive alcohol consumption, protecting your head from injury, and addressing hearing or vision problems promptly. For those with genetic risk factors identified through ApoE testing, these preventive strategies become even more important.
What natural remedies help with impaired cognitive function?
Natural approaches that support cognitive function include omega-3 fatty acids from fish oil which support brain health and reduce inflammation, B-complex vitamins particularly B12, B6, and folate for brain metabolism, vitamin E as an antioxidant, curcumin from turmeric for its anti-inflammatory properties, regular consumption of green tea with L-theanine and polyphenols, ginkgo biloba for improved blood flow to the brain, and maintaining adequate vitamin D levels through sun exposure or supplementation. Lifestyle practices like meditation, tai chi, quality sleep, staying hydrated, and engaging in puzzles or learning new skills also provide natural cognitive support, though these should complement rather than replace medical evaluation and treatment.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Testosterone 375 ng/dL
Demo results
Normal Optimal 400 - 1000 High
375 ng/dL

What this means

Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

Us vs. Them

Not overhyped or overpriced. Just comprehensive blood testing made simple and for everyone.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

1,000,000+ blood tests later, here's what our customers say

Google reviews 505 reviews Next
ApoE Genotype(11) (QSC)
Google reviews 505 reviews
$1,479 $1,154
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

Sample results

Sample image
For you & your coach Health insights Written in human language, backed by science.
Sample image
For you & your doc Classic lab report A familiar and comprehensive lab report.

Ask AI

Your 24/7 Lab Guide

Quick questions:

Which test is right for my symptoms?
What could be causing this?
When should I get tested?
A
Hi, I'm AI. I can help you find the right test, explain results, or prepare for your visit. What can I help with?
Just now
A
AI provides insights, not medical diagnoses.