Hepatitis B Immunity Blood Test

What is Immunity to Hepatitis B?

Hepatitis B immunity is protection against the Hepatitis B virus (HBV), a potentially serious infection that attacks the liver. It is acquired through successful vaccination with the Hepatitis B vaccine or recovery from a previous HBV infection. The Hepatitis B Surface Antibody Test is the most important test for confirming immunity because it measures protective antibody levels in your blood.

RECOMMENDED TEST Hepatitis B Surface Antibody Test
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What causes immunity to Hepatitis B?

Immunity to Hepatitis B is caused by your immune system producing protective antibodies called Hepatitis B surface antibodies (anti-HBs) in response to vaccination or natural infection. When you receive the Hepatitis B vaccine, your body recognizes the viral proteins and creates these antibodies without causing disease. If you recover from an actual Hepatitis B virus infection, your immune system also produces these same protective antibodies. These antibodies remain in your bloodstream and provide long-term protection by recognizing and neutralizing the virus if you're exposed again.

What is the best test for Hepatitis B immunity?

The Hepatitis B Surface Antibody Test is the most important test for confirming immunity to Hepatitis B because it directly measures the levels of protective anti-HBs antibodies in your blood. High levels of these antibodies indicate strong immunity from successful vaccination or recovery from past infection. For a simple yes-or-no answer about your immunity status, the Hepatitis B Surface Antibody Qualitative test provides a clear positive or negative result. Both tests use a blood sample to detect these specific antibodies that protect you from the virus, but the quantitative version gives you actual antibody levels which can be helpful for monitoring immunity over time.

When should I get tested for Hepatitis B immunity?

You should get tested if you work in healthcare or have occupational exposure to blood, if you're traveling to regions where Hepatitis B is common (like parts of Asia, Africa, or the Pacific Islands), if you received the Hepatitis B vaccine series and want to confirm it worked, or if you're planning pregnancy and need to verify your protection. Testing is also recommended if you're starting a job that requires proof of immunity, if you've had potential exposure to the virus through needles or bodily fluids, or if you're a close household contact of someone with Hepatitis B. Early confirmation of immunity helps you know whether you're protected or need vaccination.

What are the symptoms of Hepatitis B infection?
Hepatitis B infection symptoms include fatigue, loss of appetite, nausea and vomiting, abdominal pain especially in the upper right area near your liver, dark urine, pale or clay-colored stools, joint pain, and yellowing of your skin and eyes (jaundice). Many people with acute Hepatitis B have no symptoms at all, especially children, which is why immunity testing is so important for prevention. Chronic Hepatitis B infection may cause no symptoms for years until liver damage becomes severe, potentially leading to cirrhosis or liver cancer.
Who is at risk for Hepatitis B infection?
People at higher risk for Hepatitis B include healthcare workers exposed to blood or needles, individuals born in countries with high Hepatitis B rates, people living with someone who has Hepatitis B, individuals with multiple sexual partners or sexually transmitted infections, people who inject drugs or share needles, patients receiving dialysis, and those taking medications that suppress the immune system. Babies born to mothers with Hepatitis B are also at significant risk. If you fall into any of these categories and haven't been vaccinated, getting an immunity test can help determine if you need vaccination to protect yourself.
What happens if I'm not immune to Hepatitis B?
If you're not immune to Hepatitis B, you're vulnerable to infection with the virus, which can cause acute liver inflammation and potentially progress to chronic infection. Chronic Hepatitis B affects about 5-10% of infected adults and can lead to serious complications including cirrhosis, liver failure, and liver cancer over time. Without immunity, you risk contracting the virus through exposure to infected blood, sexual contact, or contaminated needles. The good news is that if testing shows you lack immunity, you can receive the Hepatitis B vaccine series to develop protection, which is over 90% effective in healthy adults.
Can Hepatitis B immunity be confirmed with a blood test?
Yes, Hepatitis B immunity can be definitively confirmed with a blood test that detects Hepatitis B surface antibodies (anti-HBs). This is the gold standard for verifying protection against the virus. The blood test identifies the specific antibodies your immune system produces in response to vaccination or past infection. A positive result means you have immunity, while a negative result indicates you may need vaccination or a booster dose. The test is simple, requiring only a blood sample, and provides reliable results that healthcare providers use to verify immunity status for employment, travel, or personal health purposes.
How is lack of Hepatitis B immunity addressed?
Lack of Hepatitis B immunity is addressed through vaccination with the Hepatitis B vaccine series, which typically consists of three or four doses given over six months. The vaccine contains inactive viral proteins that trigger your immune system to produce protective antibodies without causing infection. After completing the series, most people develop immunity within one to two months of the final dose. If you don't respond to the initial vaccine series, your healthcare provider may recommend a second series or higher doses. Some people who received vaccination years ago may benefit from a booster shot if antibody levels have declined significantly.
How can I prevent Hepatitis B infection?
You can prevent Hepatitis B infection by getting vaccinated with the complete Hepatitis B vaccine series, which is the most effective prevention method. Practice safe behaviors including using condoms during sexual activity, never sharing needles or personal items like razors and toothbrushes, and ensuring proper sterilization of tattoo and piercing equipment. Healthcare workers should follow universal precautions and use protective equipment when handling blood or bodily fluids. If you've been exposed to Hepatitis B and aren't immune, post-exposure prophylaxis with vaccine and immunoglobulin can prevent infection if given within 24 hours of exposure.
What can I do to maintain Hepatitis B immunity?
To maintain Hepatitis B immunity, the most important step is completing the full vaccine series if you haven't already been vaccinated. For most people, immunity from the Hepatitis B vaccine lasts for decades or even a lifetime, so routine booster shots aren't typically necessary. However, you can get periodic blood tests to check your antibody levels, especially if you're in a high-risk occupation or have immunocompromising conditions. Living a healthy lifestyle with good nutrition, adequate sleep, and stress management supports overall immune function. If testing shows your antibody levels have declined significantly and you remain at risk for exposure, discuss booster vaccination with your healthcare provider.
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Long story short:
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  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

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Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Hepatitis B Surface Antibody Test
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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