Hypersensitivity Reaction Blood Test

What is Hypersensitivity Reaction?

Hypersensitivity reaction is an exaggerated immune response to substances that are normally harmless to most people. It is caused by immune system overreaction to triggers such as medications like acetaminophen, vaccines including tetanus antitoxoid, and other environmental substances. The BasoFunction HRT Acetaminophen test is the most important test for diagnosis when medication-induced hypersensitivity is suspected.

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What causes hypersensitivity reactions?

Hypersensitivity reactions are caused by an overactive immune response to substances that are typically harmless. Common triggers include medications like acetaminophen, aspirin, and antibiotics, as well as vaccines such as tetanus antitoxoid. Environmental factors, foods, insect stings, and latex can also trigger these reactions. When your immune system mistakenly identifies these substances as threats, it releases chemicals like histamine that cause symptoms ranging from mild skin rashes to severe anaphylaxis.

What is the best test for hypersensitivity reactions?

The BasoFunction HRT Acetaminophen test is the most important test for hypersensitivity reactions when medication triggers are suspected because it specifically evaluates how your body responds to acetaminophen, one of the most common pain relievers. This specialized test measures elevated biomarker levels that indicate your immune system is overreacting to the medication. For vaccine-related reactions, the Tetanus Antitoxoid test is essential as it measures antibody levels that may indicate an allergic response to tetanus vaccination. These tests help pinpoint the exact trigger so you can avoid future exposure and manage your reactions effectively.

When should I get tested for hypersensitivity reactions?

You should get tested if you develop unexplained skin rashes, hives, or itching after taking medications like acetaminophen or receiving vaccines. Testing is also important if you experience breathing difficulties, facial swelling, or throat tightness following exposure to common substances. If you have recurring allergic symptoms but cannot identify the trigger, blood testing can help determine whether medications or vaccines are the culprit. Early identification of hypersensitivity triggers prevents future severe reactions and helps you make informed decisions about your healthcare.

What are the symptoms of hypersensitivity reactions?
Hypersensitivity reactions cause a range of symptoms depending on severity. Mild reactions include skin rashes, hives, itching, and redness that appear within hours of exposure. Moderate symptoms involve swelling of the face, lips, tongue, or throat, along with difficulty breathing or wheezing. Severe reactions, known as anaphylaxis, can cause rapid pulse, drop in blood pressure, dizziness, loss of consciousness, and life-threatening breathing problems. Some people also experience digestive symptoms like nausea, vomiting, or diarrhea when they have hypersensitivity to certain substances.
Who is at risk for hypersensitivity reactions?
People with a personal or family history of allergies, asthma, or eczema face higher risk for hypersensitivity reactions. Those who frequently take over-the-counter pain medications like acetaminophen or receive multiple vaccinations may develop sensitivities over time. Healthcare workers, laboratory personnel, and people with occupational exposures to chemicals or latex are also at increased risk. Previous allergic reactions to any substance significantly raise your chances of developing additional hypersensitivities, making it important to identify triggers early through blood testing.
What happens if hypersensitivity reactions are left untreated?
Untreated hypersensitivity reactions can progress from mild symptoms to life-threatening anaphylaxis with repeated exposure to the trigger. Chronic exposure without identifying and avoiding the culprit substance leads to persistent skin inflammation, respiratory problems, and diminished quality of life. Severe untreated reactions can cause anaphylactic shock, which results in dangerously low blood pressure, airway closure, and potential death within minutes. Identifying your specific triggers through blood testing allows you to avoid dangerous substances and carry emergency medications like epinephrine when needed.
Can hypersensitivity reactions be diagnosed with a blood test?
Yes, specialized blood tests can identify specific triggers of hypersensitivity reactions, particularly medications and vaccines. The BasoFunction HRT Acetaminophen test measures your immune response to acetaminophen, while the Tetanus Antitoxoid test evaluates antibody levels related to tetanus vaccination. These blood tests detect elevated biomarkers that indicate your immune system is overreacting to specific substances. While clinical symptoms and medical history remain important for diagnosis, blood testing provides objective evidence of hypersensitivity and helps pinpoint the exact trigger causing your reactions.
How are hypersensitivity reactions treated?
Treatment for hypersensitivity reactions begins with immediate removal of the triggering substance and avoidance of future exposure. Mild reactions are managed with antihistamines like diphenhydramine or cetirizine to reduce itching, hives, and swelling. Moderate reactions may require corticosteroids like prednisone to reduce inflammation. Severe anaphylactic reactions demand immediate epinephrine injection followed by emergency medical care. Once blood testing identifies your specific triggers, your healthcare provider creates an avoidance plan and may prescribe an epinephrine auto-injector for emergency use if you accidentally encounter the substance again.
How can I prevent hypersensitivity reactions?
Prevention starts with identifying your specific triggers through blood testing and then strictly avoiding those substances. Always inform healthcare providers, pharmacists, and dentists about your known hypersensitivities before receiving medications or vaccines. Read medication labels carefully and ask about ingredients if you have sensitivities to common pain relievers like acetaminophen. Wear a medical alert bracelet that lists your hypersensitivities so emergency responders can provide appropriate care. Carry prescribed emergency medications like epinephrine auto-injectors if you have a history of severe reactions, and educate family members on how to use them.
What can I do at home for hypersensitivity reactions?
For mild hypersensitivity reactions at home, immediately stop using the suspected trigger substance and take over-the-counter antihistamines to relieve itching and hives. Apply cool compresses to affected skin areas to reduce swelling and discomfort. Keep a symptom diary noting what you were exposed to before reactions occur, which helps identify patterns for discussion with your healthcare provider. However, if you experience difficulty breathing, throat swelling, or dizziness, seek emergency medical attention immediately rather than attempting home treatment. Blood testing helps confirm triggers so you know exactly what to avoid in the future.
How’s this work?
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Long story short:
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  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
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  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
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Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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BasoFunction™ HRT Acetaminophen
Google reviews 505 reviews
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What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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