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Hyperlipidemia is a condition characterized by abnormally high levels of lipids such as cholesterol and triglycerides in the blood. It is caused by genetic factors, dietary intake of saturated fats, obesity, diabetes, and certain medications. The Lipoprotein Fractionation NMR test is the most important test for diagnosis because it provides comprehensive analysis of all lipoprotein particles and lipid components.
Hyperlipidemia is caused by a combination of genetic factors, poor dietary habits, and lifestyle choices. Consuming too many saturated fats, trans fats, and cholesterol from foods like red meat, full-fat dairy, and processed foods elevates blood lipid levels. Additional causes include obesity, physical inactivity, type 2 diabetes, hypothyroidism, kidney disease, and certain medications like beta-blockers, diuretics, and corticosteroids. Familial hyperlipidemia is an inherited condition where genetics cause extremely high cholesterol levels from birth. Smoking and excessive alcohol consumption also contribute to abnormal lipid levels by affecting how your liver processes fats.
The Lipoprotein Fractionation NMR test is the most important test for hyperlipidemia because it provides the most comprehensive analysis of all lipoprotein particles in your blood, including LDL cholesterol, HDL cholesterol, VLDL cholesterol, and triglycerides. Unlike standard lipid panels, this advanced test measures particle size and number, which gives a more accurate assessment of your cardiovascular disease risk. The test detects subtle abnormalities in lipid metabolism that basic cholesterol tests might miss. For patients taking sirolimus or other medications that affect lipid levels, the Sirolimus LC/MS/MS test is also essential to monitor drug levels and prevent medication-induced hyperlipidemia.
You should get tested if you have a family history of high cholesterol or heart disease, are overweight or obese, have diabetes or prediabetes, or are over age 40. Get tested immediately if you experience chest pain, shortness of breath, or have been diagnosed with conditions like metabolic syndrome, hypothyroidism, or kidney disease. If you take medications known to raise cholesterol levels, including steroids, beta-blockers, or immunosuppressants like sirolimus, regular testing is crucial. Adults should have their lipid levels checked at least every five years, but those with risk factors need more frequent monitoring every six months to a year.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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