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Hodgkin's lymphoma is a type of cancer that affects the lymphatic system, which is part of the body's immune system. It is caused by the abnormal growth of Reed-Sternberg cells, large malignant lymphocytes that disrupt normal immune function. The Protein, Total and Protein Electrophoresis test is the most important blood test for monitoring Hodgkin's lymphoma because it reveals abnormal protein patterns that indicate disease activity.
Hodgkin's lymphoma is caused by the abnormal growth of Reed-Sternberg cells, which are large malignant lymphocytes that develop in the lymph nodes and other lymphatic tissues. These cancerous cells crowd out healthy immune cells and disrupt the normal function of the lymphatic system. While the exact trigger is unknown, certain risk factors increase susceptibility, including Epstein-Barr virus infection, weakened immune system, and family history of the disease.
The Protein, Total and Protein Electrophoresis test is the most important blood test for monitoring Hodgkin's lymphoma because it reveals abnormal protein patterns that indicate disease activity and immune system changes. This comprehensive analysis detects alterations in protein production and distribution caused by the cancer's effect on the lymphatic system. The Interleukin-2 Receptor Alpha Chain (IL-2Ra/CD25) test is also essential for tracking disease progression, as it measures biomarkers of T-cell activation that become elevated when Hodgkin's lymphoma is active. While tissue biopsy and imaging confirm diagnosis, these blood tests provide critical information for monitoring treatment response and detecting disease changes over time.
You should get tested if you experience persistent swollen lymph nodes in your neck, armpits, or groin that last more than two weeks, especially if accompanied by unexplained fever, drenching night sweats, or unintentional weight loss. Get tested immediately if you notice painless lumps combined with extreme fatigue, persistent itching without rash, or chest pain and difficulty breathing. Testing is also important if you have a family history of lymphoma or have been diagnosed with Epstein-Barr virus, as early monitoring can help detect disease progression.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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