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Herpetic whitlow is a painful viral infection that causes blisters on the fingers and thumbs. It is caused by herpes simplex virus type 1 (HSV-1) or herpes simplex virus type 2 (HSV-2). The Herpes Simplex Virus 1 and 2 IgG with Reflex to HSV-2 Inhibition test is the most important test for diagnosis because it identifies which specific viral strain is causing the infection.
Herpetic whitlow is caused by herpes simplex virus type 1 (HSV-1) or herpes simplex virus type 2 (HSV-2) entering through small cuts or breaks in the skin of the fingers or thumbs. HSV-1 is the same virus that commonly causes cold sores around the mouth, while HSV-2 typically causes genital herpes. The infection most often occurs when someone touches an active herpes sore on their own body or comes into contact with infected bodily fluids, which is why healthcare workers, dental professionals, and people who bite their nails or suck their thumbs are at higher risk.
The Herpes Simplex Virus 1 and 2 IgG with Reflex to HSV-2 Inhibition test is the most important blood test for herpetic whitlow because it detects antibodies against both HSV-1 and HSV-2 and identifies which specific viral strain is causing your infection. This test looks for IgG antibodies that your immune system produces in response to herpes infection, and the reflex to HSV-2 inhibition provides additional specificity to confirm whether HSV-2 is present. Knowing which virus type you have helps your doctor understand the likely source of infection, predict recurrence patterns, and provide appropriate counseling about transmission risks to others.
You should get tested if you develop painful blisters or fluid-filled sores on your fingers or thumbs, especially if you have a history of oral or genital herpes, work in healthcare or dentistry, or have recently had contact with someone who has active herpes sores. Testing is also important if you experience burning, tingling, or redness on your finger before blisters appear, or if you have recurrent episodes of painful finger lesions. Early testing helps confirm the diagnosis, allows you to start treatment quickly to reduce symptoms and healing time, and prevents you from unknowingly spreading the virus to other parts of your body or to other people.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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