Herpes Simplex Virus Type 2 Blood Test

What is Herpes Simplex Virus Type 2 Infection?

Herpes Simplex Virus Type 2 infection is a sexually transmitted infection that primarily causes genital herpes. It is caused by the HSV-2 virus, which infects the genital area and remains dormant in nerve cells, causing recurrent outbreaks. The Herpes Simplex Virus 2 IgG Type-Specific Antibody test is the most important test for diagnosis because it detects antibodies even when symptoms are not present.

RECOMMENDED TEST Herpes Simplex Virus 2 (IgG), Type-Specific Antibody
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What causes Herpes Simplex Virus Type 2 infection?

Herpes Simplex Virus Type 2 infection is caused by the HSV-2 virus, which spreads through sexual contact with an infected person. The virus enters the body through small breaks in the skin or mucous membranes of the genital area and travels to nerve cells where it remains dormant. Even when no visible sores are present, the virus can still be transmitted to partners through viral shedding, making it one of the most common sexually transmitted infections worldwide.

What is the best test for HSV-2 infection?

The Herpes Simplex Virus 2 IgG Type-Specific Antibody test is the most important test for HSV-2 infection because it detects antibodies that your immune system produces in response to the virus. This test can identify infection even when you have no symptoms or visible sores, which is crucial since many people with HSV-2 are asymptomatic. For comprehensive screening, the Herpes Simplex Virus 1 and 2 IgG with Reflex to HSV-2 Inhibition test is also valuable because it tests for both HSV-1 and HSV-2 antibodies and includes confirmatory testing to accurately distinguish between the two virus types.

When should I get tested for HSV-2?

You should get tested if you have had unprotected sex with a new or multiple partners, have noticed unusual genital sores or blisters, have a partner diagnosed with genital herpes, or are experiencing symptoms like painful urination or genital itching. Testing is also recommended if you are pregnant or planning pregnancy, as HSV-2 can be transmitted to a baby during delivery. Even if you have no symptoms, consider testing if you want to know your status before starting a new relationship.

What are the symptoms of HSV-2 infection?
HSV-2 symptoms include painful blisters or sores on the genitals, buttocks, or thighs that break open and form ulcers before healing. You might notice flu-like symptoms during the first outbreak, including fever, body aches, and swollen lymph nodes. Other symptoms include painful urination, genital itching or tingling before sores appear, and abnormal vaginal discharge. Many people with HSV-2 have very mild symptoms that go unnoticed or mistake them for other skin conditions like ingrown hairs or pimples.
Who is at risk for HSV-2 infection?
Anyone who is sexually active is at risk for HSV-2, but risk increases with multiple sexual partners, unprotected sex, and having other sexually transmitted infections. Women are more susceptible to infection than men due to anatomical differences. People with weakened immune systems, those who started having sex at a young age, and individuals whose partners have genital herpes face higher risk. Having HSV-1 (oral herpes) does not protect against getting HSV-2, and you can have both types simultaneously.
What happens if HSV-2 is left untreated?
If left untreated, HSV-2 causes recurrent outbreaks that can be painful and emotionally distressing, though outbreaks typically become less frequent and severe over time. Untreated HSV-2 significantly increases your risk of acquiring or transmitting HIV because the genital sores provide entry points for the virus. In pregnant women, untreated HSV-2 can lead to neonatal herpes if transmitted to the baby during delivery, which can cause serious complications including brain damage or death. The infection also increases susceptibility to other sexually transmitted infections.
Can HSV-2 be diagnosed with a blood test?
Yes, HSV-2 can be definitively diagnosed with a blood test that detects IgG antibodies specific to the virus. Blood tests are particularly valuable because they can identify infection even when you have no symptoms or visible sores, unlike swab tests that require active lesions. The antibodies typically develop within a few weeks to a few months after initial infection and remain detectable for life. Type-specific blood tests can accurately distinguish between HSV-1 and HSV-2, which is important for understanding transmission risks and appropriate treatment.
How is HSV-2 infection treated?
HSV-2 is treated with antiviral medications like acyclovir, valacyclovir, or famciclovir that reduce the severity and duration of outbreaks. For frequent outbreaks, daily suppressive therapy can reduce recurrence rates by 70-80% and significantly decrease the risk of transmitting the virus to partners. While these medications cannot cure HSV-2 or eliminate the virus from your body, they effectively manage symptoms and prevent complications. Treatment should be started as soon as symptoms appear during an outbreak for best results, and pregnant women with HSV-2 may need suppressive therapy near delivery to prevent transmission to the baby.
How can I prevent HSV-2 infection?
You can prevent HSV-2 by using condoms consistently during all sexual activity, though condoms do not provide complete protection since the virus can be present on areas not covered by condoms. Avoid sexual contact when you or your partner have visible sores or symptoms of an outbreak. Having open conversations with partners about STI status and getting tested together before becoming sexually active reduces risk. If you have HSV-2, taking daily antiviral suppressive therapy significantly reduces the likelihood of transmitting the virus to uninfected partners.
What can I do at home for HSV-2 outbreaks?
During HSV-2 outbreaks, keep the affected area clean and dry, and wear loose-fitting cotton underwear to reduce irritation. Apply cool compresses or take warm baths to soothe painful sores, and try over-the-counter pain relievers like ibuprofen or acetaminophen for discomfort. Avoid touching sores and wash hands frequently to prevent spreading the virus to other body parts. Reduce outbreak triggers by managing stress, getting adequate sleep, eating a balanced diet, and avoiding excessive sun exposure to the genital area, as these factors can weaken your immune system and trigger recurrences.
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  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

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Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
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During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Herpes Simplex Virus 2 (IgG), Type-Specific Antibody
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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