Hepatitis C Reinfection Blood Test

What is Hepatitis C reinfection?

Hepatitis C reinfection occurs when someone who has been successfully treated for Hepatitis C becomes infected with the virus again. It is caused by re-exposure to the Hepatitis C virus (HCV) through injection drug use, contaminated needles, or high-risk behaviors after achieving sustained virologic response. The Hepatitis C Viral RNA Quantitative Real-Time PCR is the most important test for diagnosing reinfection because it directly detects and measures viral RNA in the blood.

RECOMMENDED TEST Hepatitis C Viral RNA, Quantitative Real-Time PCR
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What causes Hepatitis C reinfection?

Hepatitis C reinfection is caused by re-exposure to the Hepatitis C virus (HCV) after successfully completing treatment. This happens most commonly through sharing needles or drug injection equipment, receiving unsterilized tattoos or piercings, or sharing personal items like razors that may have infected blood. Even after achieving a cure with sustained virologic response, your body does not develop lasting immunity to HCV, meaning you can get infected again if exposed to the virus.

What is the best test for Hepatitis C reinfection?

The Hepatitis C Viral RNA Quantitative Real-Time PCR is the most important test for Hepatitis C reinfection because it directly detects and measures the amount of virus in your blood. After successful treatment, your HCV RNA levels should be undetectable, so if this test finds the virus again, it confirms reinfection rather than treatment failure. This highly sensitive test not only detects the presence of the virus but also quantifies the viral load, which helps your doctor plan the most effective retreatment strategy.

When should I get tested for Hepatitis C reinfection?

You should get tested if you have been successfully treated for Hepatitis C but continue to have risk factors for re-exposure. This includes ongoing injection drug use, sharing needles or drug equipment, getting tattoos or piercings in unregulated settings, or working in healthcare with blood exposure. Healthcare providers typically recommend periodic testing every 6 to 12 months for people at continued risk, and immediately if you have a known exposure event or develop symptoms like fatigue, jaundice, or abdominal pain.

What are the symptoms of Hepatitis C reinfection?
Hepatitis C reinfection often causes no symptoms in the early stages, which is why regular blood testing is crucial for people at risk. When symptoms do appear, you might notice fatigue, loss of appetite, nausea, joint pain, dark urine, or jaundice (yellowing of the skin and eyes). Some people experience flu-like symptoms such as fever and body aches. Because symptoms can be mild or absent, many people do not realize they have been reinfected until blood tests detect the virus.
Who is at risk for Hepatitis C reinfection?
People who inject drugs or share needles are at highest risk for Hepatitis C reinfection, as this is the most common transmission route. Healthcare workers with exposure to blood, people receiving hemodialysis, individuals with HIV or who engage in high-risk sexual behaviors, and those living with someone who has active Hepatitis C infection are also at increased risk. Anyone who was previously treated successfully but returns to behaviors involving blood contact can become reinfected since the body does not develop lasting immunity to HCV.
What happens if Hepatitis C reinfection is left untreated?
Untreated Hepatitis C reinfection can lead to chronic liver inflammation, progressive liver scarring (fibrosis), cirrhosis, liver failure, and liver cancer. The liver damage from reinfection can accumulate on top of any scarring from the previous infection, potentially accelerating disease progression. Chronic Hepatitis C also increases the risk of developing type 2 diabetes, kidney disease, and certain blood disorders. Early detection and retreatment are highly effective at preventing these serious complications and achieving cure again.
Can Hepatitis C reinfection be diagnosed with a blood test?
Yes, Hepatitis C reinfection is diagnosed with blood tests, specifically the HCV RNA test. This test detects the genetic material of the Hepatitis C virus in your blood and measures the viral load. After successful treatment, your HCV RNA should be undetectable, so finding it again indicates reinfection. The quantitative PCR test is the gold standard because it is extremely sensitive and can detect even small amounts of virus, allowing for early diagnosis and prompt retreatment.
How is Hepatitis C reinfection treated?
Hepatitis C reinfection is treated with direct-acting antiviral (DAA) medications, the same class of drugs used for initial infections. These oral medications are highly effective, typically achieving cure rates above 95 percent with treatment courses lasting 8 to 12 weeks. Your doctor will select the specific DAA regimen based on the viral genotype, your liver health, and any previous treatments. Retreatment is generally very successful, and many people achieve sustained virologic response again, meaning the virus becomes undetectable and stays that way after treatment ends.
How can I prevent Hepatitis C reinfection?
Preventing Hepatitis C reinfection requires avoiding exposure to infected blood. If you inject drugs, use new sterile needles and equipment every time, and never share needles, syringes, or other drug paraphernalia. Get tattoos and piercings only at licensed facilities that follow proper sterilization procedures. Do not share personal items that might have blood on them, such as razors, toothbrushes, or nail clippers. If you work in healthcare, follow universal precautions and use appropriate protective equipment when handling blood or bodily fluids.
What can I do at home to support liver health after Hepatitis C treatment?
Supporting your liver health at home involves avoiding alcohol completely, as it accelerates liver damage. Maintain a healthy weight through balanced nutrition and regular exercise, as obesity can worsen liver disease. Avoid medications and supplements that can harm the liver without consulting your doctor first, including acetaminophen in high doses. Stay hydrated, eat plenty of fruits and vegetables, and consider foods that support liver function like leafy greens, fatty fish, nuts, and olive oil. Getting adequate sleep and managing stress also help your body maintain optimal liver function.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
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Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Hepatitis C Viral RNA, Quantitative Real-Time PCR
Google reviews 505 reviews
$1,701 $1,327
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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