What causes a Hepatitis B negative result?

A Hepatitis B negative result is caused by the absence of exposure to the Hepatitis B virus through vaccination or natural infection. When your immune system has never encountered the virus, your blood will not contain antibodies or antigens related to Hepatitis B. This means you currently have no immunity protection against Hepatitis B infection and may be vulnerable to contracting the virus if exposed.

What is the best test for confirming Hepatitis B negative status?

The Hepatitis Be Antibody test is the most important confirmatory test for Hepatitis B negative status because it detects whether you have ever been exposed to the virus. This test measures specific antibodies that would be present if you had previous infection or successful vaccination. When combined with other Hepatitis B markers, it provides a complete immunity profile and helps determine if you need the Hepatitis B vaccine series. A negative result on this test confirms you have no previous exposure and should consider vaccination for protection.

When should I get tested for Hepatitis B immunity?

You should get tested if you work in healthcare or are frequently exposed to blood or body fluids, are planning pregnancy or are currently pregnant, have a sexual partner with Hepatitis B, or are unsure about your vaccination history. Testing is also important before starting certain medications that suppress your immune system, or if you were born in countries where Hepatitis B is common. Getting tested helps you know if you need vaccination to protect yourself from this serious liver infection.

What are the symptoms of Hepatitis B infection?

Hepatitis B infection often causes no symptoms initially, which is why testing is so important. When symptoms do appear, you might notice yellowing of the skin and eyes (jaundice), extreme fatigue, dark urine, abdominal pain in the liver area, loss of appetite, nausea and vomiting, or joint pain. Some people develop a low-grade fever or clay-colored stools. However, many people with Hepatitis B remain symptom-free for years while the virus silently damages their liver.

Who is at risk for Hepatitis B infection?

Healthcare workers who handle blood or needles face higher risk of Hepatitis B exposure. People who share needles for drug use, have multiple sexual partners, or have unprotected sex are at increased risk. Infants born to mothers with Hepatitis B can contract the virus during birth. Those who live with someone infected with Hepatitis B, receive dialysis treatment, or travel frequently to countries with high Hepatitis B rates should consider vaccination. People who were never vaccinated and have no natural immunity remain vulnerable to infection.

What happens if Hepatitis B infection is left untreated?

Untreated Hepatitis B can progress to chronic infection in about 5-10% of adults, leading to serious liver damage over time. Chronic Hepatitis B significantly increases your risk of developing cirrhosis, where healthy liver tissue is replaced by scar tissue that cannot function properly. The infection also dramatically raises your risk of liver cancer (hepatocellular carcinoma), which can be fatal. Some people develop liver failure requiring a transplant. Early detection through blood testing and vaccination for those without immunity can prevent these severe complications.

Can Hepatitis B immunity be diagnosed with a blood test?

Yes, blood tests are the standard method for determining Hepatitis B immunity status. The Hepatitis Be Antibody test, along with other Hepatitis B marker tests, can definitively show whether you have immunity from vaccination or previous infection. These blood tests detect specific antibodies and antigens that reveal your complete Hepatitis B status. A comprehensive panel of Hepatitis B tests provides clear answers about whether you are protected, currently infected, or vulnerable to infection.

How is lack of Hepatitis B immunity addressed?

If you test negative for Hepatitis B immunity, the Hepatitis B vaccine series is the recommended treatment. The standard vaccine schedule involves three shots given over six months - the first dose, a second dose one month later, and a third dose six months after the first. For some people who need faster protection, an accelerated schedule is available. After completing the series, a follow-up blood test confirms that you developed protective antibodies. The vaccine is highly effective and provides long-lasting immunity.

How can I prevent Hepatitis B infection?

Getting the Hepatitis B vaccine series is the most effective prevention method if you test negative for immunity. Always practice safe sex by using condoms and limiting sexual partners. Never share needles, razors, toothbrushes, or other items that might have blood on them. Healthcare workers should strictly follow safety protocols when handling blood or body fluids. If you live with someone who has Hepatitis B, all household members should be vaccinated. Pregnant women should be tested so infants can receive immediate treatment if needed to prevent mother-to-child transmission.

What can I do at home while waiting to get vaccinated?

While waiting to start or complete your Hepatitis B vaccination series, maintain excellent hygiene practices and avoid potential exposure situations. Keep any cuts or wounds covered with waterproof bandages, especially in public areas. Avoid sharing personal care items like razors, nail clippers, or earrings that could have blood on them. Practice safe sex consistently until you are fully vaccinated and confirmed immune. Support your liver health by avoiding alcohol, eating a balanced diet rich in fruits and vegetables, and maintaining a healthy weight. Stay informed about Hepatitis B risks in your workplace or travel destinations.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

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Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Hepatitis B Negative Blood Test

What is Hepatitis B Negative?

Hepatitis B negative results indicate no current infection or immunity markers were detected in initial screening tests. This means you have not been exposed to the Hepatitis B virus through either vaccination or natural infection. The Hepatitis Be Antibody test is the most important confirmatory test for determining complete immunity status and vaccination needs.

Written by Private MD Labs Medical Team

Last updated: December 29, 2025

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

support@privatemdlabs.com