Hashimoto's Thyroiditis Blood Test

What is Hashimoto's Thyroiditis?

Hashimoto's thyroiditis is an autoimmune disorder where the immune system attacks the thyroid gland, leading to chronic inflammation and hypothyroidism. It is caused by the production of thyroid peroxidase (TPO) antibodies and thyroglobulin antibodies that target thyroid proteins and damage the gland. The Thyroid Peroxidase (TPO) and Thyroglobulin Antibodies test is the most important test for diagnosing Hashimoto's thyroiditis because it detects both primary autoimmune markers.

RECOMMENDED TEST Thyroid Peroxidase (TPO) and Thyroglobulin Antibodies (TAA)
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What causes Hashimoto's thyroiditis?

Hashimoto's thyroiditis is caused by an autoimmune reaction where your immune system produces antibodies that attack the thyroid gland. Specifically, thyroid peroxidase (TPO) antibodies and thyroglobulin antibodies target thyroid proteins, causing chronic inflammation and progressive damage to the gland. This autoimmune attack gradually destroys thyroid tissue, reducing the gland's ability to produce essential thyroid hormones like T3 and T4, ultimately leading to hypothyroidism.

What is the best test for Hashimoto's thyroiditis?

The Thyroid Peroxidase (TPO) and Thyroglobulin Antibodies test is the most important test for Hashimoto's thyroiditis because it detects both primary autoimmune markers in a single panel. TPO antibodies are present in about 90% of people with Hashimoto's and indicate that your immune system is attacking the enzyme responsible for thyroid hormone production. Thyroglobulin antibodies provide additional confirmation of the autoimmune attack on thyroid proteins. Together, elevated levels of these antibodies definitively confirm the autoimmune nature of the condition and distinguish Hashimoto's from other causes of thyroid dysfunction.

When should I get tested for Hashimoto's thyroiditis?

You should get tested if you experience persistent fatigue, unexplained weight gain, cold intolerance, dry skin, hair loss, or depression. Testing is especially important if you have a family history of thyroid disease or other autoimmune conditions, if you are a woman of childbearing age planning pregnancy, or if you notice a visible swelling in your neck (goiter). Early detection through antibody testing helps prevent complications and allows for timely treatment before significant thyroid damage occurs.

What are the symptoms of Hashimoto's thyroiditis?
Hashimoto's thyroiditis symptoms develop gradually and include persistent fatigue, unexplained weight gain despite normal eating, sensitivity to cold temperatures, constipation, dry skin, thinning hair, muscle aches, joint pain, depression, brain fog, and heavy or irregular menstrual periods. You might also notice facial puffiness, a slowed heart rate, or an enlarged thyroid gland (goiter) creating a visible swelling at the base of your neck. Many people experience these symptoms for months or years before seeking diagnosis because they develop so slowly.
Who is at risk for Hashimoto's thyroiditis?
Women are seven times more likely than men to develop Hashimoto's thyroiditis, especially between ages 30 and 50. Your risk increases if you have a family history of thyroid disease or other autoimmune conditions like type 1 diabetes, rheumatoid arthritis, or celiac disease. People with excessive iodine intake, radiation exposure to the neck area, or who have recently given birth are also at higher risk. Having one autoimmune condition significantly increases your chances of developing additional autoimmune disorders, including Hashimoto's.
What happens if Hashimoto's thyroiditis is left untreated?
Untreated Hashimoto's thyroiditis leads to progressive hypothyroidism with worsening symptoms and serious health complications. You face increased risks of heart disease due to elevated cholesterol and slowed heart rate, infertility and pregnancy complications including miscarriage, mental health issues like severe depression, and myxedema (a rare, life-threatening condition causing extreme cold intolerance and unconsciousness). Long-term untreated disease can cause goiter enlargement that interferes with breathing and swallowing, permanent cognitive impairment, and significantly reduced quality of life.
Can Hashimoto's thyroiditis be diagnosed with a blood test?
Yes, Hashimoto's thyroiditis is definitively diagnosed with blood tests that detect specific thyroid antibodies. The blood tests measure thyroid peroxidase (TPO) antibodies and thyroglobulin antibodies, which are elevated in people with Hashimoto's and confirm the autoimmune attack on the thyroid. Your doctor will also check thyroid hormone levels including TSH, free T4, and total T3 to assess how much the autoimmune process has affected thyroid function. Blood testing is the gold standard for diagnosis and requires no imaging or invasive procedures.
How is Hashimoto's thyroiditis treated?
Hashimoto's thyroiditis is treated with daily thyroid hormone replacement medication, typically levothyroxine (synthetic T4), which replaces the hormones your thyroid can no longer produce adequately. Your doctor will start you on a specific dose based on your TSH and thyroid hormone levels, then monitor and adjust the dosage every 6-8 weeks until optimal levels are achieved. Once stabilized, you will need annual blood tests to ensure your medication dose remains appropriate. Treatment is lifelong for most people, but it effectively manages symptoms and prevents complications when taken consistently.
How can I prevent Hashimoto's thyroiditis?
Hashimoto's thyroiditis cannot be completely prevented because it results from genetic predisposition and autoimmune factors beyond your control. However, you can reduce your risk by maintaining adequate but not excessive iodine intake, managing stress through relaxation techniques and regular exercise, avoiding smoking, and treating other autoimmune conditions promptly. If you have a family history of thyroid disease, regular screening with thyroid antibody tests allows for early detection and treatment before significant thyroid damage occurs.
What natural remedies help with Hashimoto's thyroiditis?
While natural approaches cannot replace thyroid hormone medication, certain strategies support thyroid health and symptom management. Selenium supplementation (200 mcg daily) has been shown to reduce TPO antibody levels and inflammation in some studies. Following an anti-inflammatory diet rich in vegetables, fruits, omega-3 fatty acids, and avoiding processed foods may help reduce autoimmune activity. Some people benefit from eliminating gluten, especially if they have celiac disease or gluten sensitivity. Stress reduction through yoga, meditation, and adequate sleep (7-9 hours nightly) supports immune system balance. Always discuss supplements with your doctor as some can interfere with thyroid medication absorption.
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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Thyroid Peroxidase (TPO) and Thyroglobulin Antibodies (TAA)
Google reviews 505 reviews
$110 $86
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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