Food Protein-Induced Enterocolitis Syndrome (FPIES) is a severe non-IgE mediated food allergy causing delayed vomiting, diarrhea, and potentially life-threatening shock. It is caused by an abnormal T-cell mediated immune response to specific food proteins, most commonly milk, soy, rice, and certain fish. The Allergen Specific IgE Rice Wild test is the most important test for identifying rice as a trigger food in FPIES patients.
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FPIES is caused by an abnormal T-cell mediated immune response to specific food proteins that triggers severe inflammation in the gastrointestinal tract. Unlike typical food allergies that involve IgE antibodies and cause immediate reactions, FPIES involves a delayed cell-mediated immune response that typically occurs 2-4 hours after eating the trigger food. Common trigger foods include cow milk, soy, rice, oats, barley, chicken, turkey, fish, eggs, and certain vegetables, with infants and young children being most commonly affected.
The Allergen Specific IgE Rice Wild test is the most important test for FPIES because it detects IgE antibodies against rice proteins, one of the most common trigger foods in infants and children with this condition. While FPIES is primarily diagnosed through clinical evaluation and supervised oral food challenges rather than blood tests alone, allergen-specific testing helps identify potential trigger foods and guide elimination diets. Additional supportive tests include the Allergen Specific IgE Tilapia test for fish protein sensitivities and the Lemon IgG test for citrus sensitivities, as some FPIES patients react to multiple food categories. These blood tests provide valuable information to help healthcare providers develop safe dietary management plans and avoid dangerous food exposures.
You should get tested if your infant or child experiences repetitive vomiting 2-4 hours after eating specific foods, especially if accompanied by diarrhea, lethargy, or pale skin. Testing is particularly important if your child has had an episode of severe vomiting leading to dehydration or shock after eating rice, soy, milk, or fish. You should also consider testing if you notice a pattern of delayed gastrointestinal reactions that occur consistently with certain foods, if your child has failure to thrive or poor weight gain, or if there is a family history of food allergies and your child shows signs of food intolerance.
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What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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