Eosinophilic esophagitis is a chronic immune disorder where eosinophils, a type of white blood cell, accumulate in the esophagus causing inflammation and swallowing difficulties. It is caused by allergic reactions to specific food proteins such as dairy, wheat, eggs, and soy, or environmental allergens like pollen and dust mites. Allergen-specific IgE and IgG antibody testing are the most important tests for identifying trigger foods and environmental allergens that cause this condition.
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Eosinophilic esophagitis is caused by allergic reactions to specific food proteins and environmental allergens that trigger your immune system to send eosinophils to attack the esophagus lining. Common food triggers include dairy products, wheat, eggs, soy, nuts, and fish, while environmental triggers can include pollen, dust mites, mold, and animal dander. When you eat or breathe in these allergens, your body mistakes them for harmful invaders and floods the esophagus with eosinophils, causing chronic inflammation and tissue damage that makes swallowing painful and difficult.
Allergen-specific IgE and IgG antibody testing are the most important blood tests for eosinophilic esophagitis because they identify exactly which foods and environmental allergens are triggering your immune reaction. The Allergen Specific IgE Cream Cheese test detects immediate allergic reactions to dairy proteins, while Food Specific IgG tests like the Buckwheat panel identify delayed sensitivity reactions that contribute to chronic inflammation. Testing for common trigger foods like tilapia with the Allergen Specific IgE Tilapia test, along with environmental allergens like the Goose Feathers IgG test, helps create a comprehensive picture of all your triggers. While endoscopy and biopsy are needed to confirm the diagnosis, these blood tests are essential for developing an effective elimination diet and treatment plan.
You should get tested if you experience difficulty swallowing solid foods, feel like food is getting stuck in your throat or chest, have frequent heartburn that does not respond to acid reflux medications, or need to drink liquids constantly to help food go down. Parents should consider testing for children who refuse to eat, chew food excessively long, or have feeding problems and poor weight gain. Getting tested early is important because untreated eosinophilic esophagitis can lead to permanent esophageal narrowing and scarring that makes swallowing increasingly difficult over time.
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What this means
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Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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