Depression and Mood Disorders Blood Test

What is Depression and Mood Disorders?

Depression and mood disorders are mental health conditions characterized by persistent feelings of sadness, hopelessness, and loss of interest in daily activities. These conditions are caused by imbalances in neurotransmitters such as serotonin, dopamine, and norepinephrine, which can be affected by nutritional deficiencies including vitamin B6. The Vitamin B6 blood test is the most important nutritional test for mood disorders because it measures a critical cofactor in neurotransmitter synthesis.

RECOMMENDED TEST Vitamin B6
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What causes depression and mood disorders?

Depression and mood disorders are caused by imbalances in brain neurotransmitters such as serotonin, dopamine, and norepinephrine. These chemical messengers regulate mood, sleep, appetite, and emotional responses. Nutritional deficiencies, particularly vitamin B6, can disrupt neurotransmitter production and worsen symptoms. Other contributing factors include genetic predisposition, chronic stress, hormonal changes, and inflammatory processes in the brain that affect neural signaling.

What is the best test for depression and mood disorders?

The Vitamin B6 test is the most important nutritional blood test for depression and mood disorders because it measures a critical cofactor required for neurotransmitter synthesis. Vitamin B6 is directly involved in converting amino acids into serotonin, dopamine, GABA, and norepinephrine - the brain chemicals that regulate mood and emotional well-being. Low B6 levels can impair this conversion process and contribute to depressive symptoms. While depression itself is diagnosed through clinical evaluation, identifying and correcting vitamin B6 deficiency through blood testing can be an essential component of comprehensive mental health treatment and may help improve response to therapy.

When should I get tested for depression-related nutritional deficiencies?

You should get tested if you experience persistent sadness, loss of interest in activities you once enjoyed, changes in sleep or appetite, fatigue, difficulty concentrating, or feelings of worthlessness lasting more than two weeks. Testing is especially important if you have tried treatment without improvement, have risk factors like poor diet or digestive issues affecting nutrient absorption, or want to identify any nutritional deficiencies that may be contributing to your symptoms. Early testing helps ensure you address all potential factors affecting your mental health.

What are the symptoms of depression and mood disorders?
Depression symptoms include persistent sadness or empty mood, loss of interest in activities, significant weight changes or appetite disturbances, sleep problems such as insomnia or oversleeping, fatigue and low energy, feelings of worthlessness or excessive guilt, difficulty thinking or concentrating, and recurrent thoughts of death or suicide. You might also experience physical symptoms like headaches, digestive problems, or unexplained aches and pains. Mood disorders can also cause irritability, restlessness, or mood swings between emotional highs and lows.
Who is at risk for depression and mood disorders?
People with a family history of depression, those who have experienced trauma or significant life stress, and individuals with chronic medical conditions face higher risk. Women are twice as likely as men to experience depression due to hormonal fluctuations during menstruation, pregnancy, and menopause. Those with poor nutrition, vitamin deficiencies, substance abuse problems, or certain medications also have increased risk. Social isolation, unemployment, financial stress, and lack of social support further elevate the likelihood of developing mood disorders.
What happens if depression is left untreated?
Untreated depression can worsen over time and lead to serious complications including suicide risk, substance abuse as self-medication, relationship problems and social isolation, inability to work or function in daily life, and development of chronic physical health problems. Depression increases the risk of heart disease, diabetes, and weakened immune function. It can cause permanent changes in brain structure and chemistry that make future episodes more likely and harder to treat. Early intervention and addressing nutritional factors like vitamin B6 deficiency significantly improve outcomes and prevent these complications.
Can depression be diagnosed with a blood test?
Depression itself cannot be diagnosed with a blood test, as it is a clinical diagnosis based on psychological evaluation and symptom assessment by a mental health professional. However, blood tests play an important role in identifying nutritional deficiencies and biochemical imbalances that may contribute to depressive symptoms. The Vitamin B6 test specifically measures levels of this essential nutrient needed for neurotransmitter production. Testing helps rule out medical conditions that mimic depression and identifies correctable factors that may be worsening your mood symptoms as part of comprehensive treatment.
How is depression treated?
Depression is treated through a combination of approaches including psychotherapy such as cognitive behavioral therapy, antidepressant medications that balance neurotransmitters, and lifestyle modifications. Addressing nutritional deficiencies through supplementation when blood tests reveal low vitamin B6 or other nutrients supports neurotransmitter production and may enhance treatment effectiveness. Regular exercise, adequate sleep, stress management techniques, and strong social support are also crucial components. Treatment is individualized based on symptom severity, and many people benefit from a combination of therapy, medication, and nutritional support for optimal recovery.
How can I prevent depression and mood disorders?
Prevention strategies include maintaining a nutrient-rich diet with adequate B vitamins, omega-3 fatty acids, and protein to support brain health and neurotransmitter production. Regular physical exercise, consistent sleep schedules, stress management through mindfulness or meditation, and maintaining strong social connections all protect mental health. Limiting alcohol consumption, avoiding recreational drugs, and addressing vitamin deficiencies through testing and supplementation when needed are also important. Early intervention when symptoms first appear and building healthy coping mechanisms for stress can prevent mild mood changes from developing into clinical depression.
What natural remedies help with depression?
Natural approaches that support mental health include ensuring adequate vitamin B6 intake through foods like poultry, fish, potatoes, chickpeas, and bananas, or supplementation if blood tests show deficiency. Regular exercise releases endorphins and boosts mood naturally. Omega-3 fatty acids from fish oil support brain function and may reduce depressive symptoms. Sunlight exposure or vitamin D supplementation, maintaining stable blood sugar through balanced meals, practicing mindfulness meditation, and getting quality sleep all help regulate mood. These natural remedies work best as complements to professional treatment rather than replacements, especially for moderate to severe depression.
How’s this work?
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Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
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  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Vitamin B6
Google reviews 505 reviews
$136 $106
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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