Cow's Milk Allergy Blood Test

What is Cow's Milk Allergy?

Cow's milk allergy is an immune system reaction to proteins found in cow's milk, particularly casein and whey proteins like beta-lactoglobulin. It is caused by the immune system mistakenly producing IgE antibodies against milk proteins, triggering allergic reactions ranging from hives and digestive upset to life-threatening anaphylaxis. The Food Allergen Profile IgE With Component Reflexes is the most important test for diagnosis because it detects specific IgE antibodies to cow's milk proteins.

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What causes cow's milk allergy?

Cow's milk allergy is caused by the immune system mistakenly identifying milk proteins as harmful invaders and producing IgE antibodies to attack them. The two main protein groups in cow's milk that trigger allergic reactions are casein (found in the solid part of milk) and whey proteins like beta-lactoglobulin and alpha-lactalbumin. When someone with cow's milk allergy consumes milk or dairy products, their immune system launches an attack against these proteins, releasing histamine and other chemicals that cause allergic symptoms ranging from mild skin rashes to severe anaphylaxis.

What is the best test for cow's milk allergy?

The Food Allergen Profile IgE With Component Reflexes is the most important test for cow's milk allergy because it detects specific IgE antibodies to cow's milk proteins, confirming whether your immune system is truly allergic to milk. This comprehensive blood test measures IgE levels to cow's milk (F2) and can identify which specific milk protein components are triggering your reactions, helping predict the severity of allergic responses and risk of anaphylaxis. For additional insight into specific protein sensitivities, the Beta lactoglobulin IgG test can measure immune responses to this major whey protein, which is particularly useful for understanding reactions to processed dairy products where this protein remains present.

When should I get tested for cow's milk allergy?

You should get tested if you or your child experiences symptoms like hives, swelling, vomiting, diarrhea, wheezing, or difficulty breathing within minutes to hours after consuming milk or dairy products. Testing is especially important for infants and young children who develop eczema, persistent digestive problems, or failure to thrive, as cow's milk allergy is one of the most common food allergies in early childhood. You should also consider testing if you have a family history of food allergies or other allergic conditions, or if you have experienced any severe reaction to dairy that could indicate risk for anaphylaxis.

What are the symptoms of cow's milk allergy?
Symptoms of cow's milk allergy typically appear within minutes to hours after consuming milk or dairy products and can affect multiple body systems. Skin reactions include hives, itching, eczema, and swelling of the lips, face, or tongue. Digestive symptoms include nausea, vomiting, abdominal cramps, diarrhea, and in infants, colic or blood in stools. Respiratory symptoms can include wheezing, coughing, runny nose, and difficulty breathing. In severe cases, cow's milk allergy can cause anaphylaxis, a life-threatening reaction involving multiple symptoms, a sudden drop in blood pressure, and loss of consciousness requiring immediate emergency treatment.
Who is at risk for cow's milk allergy?
Infants and young children are at highest risk for cow's milk allergy, with most cases developing in the first year of life. Children with a family history of food allergies, eczema, asthma, or hay fever have an increased likelihood of developing milk allergy. Other risk factors include having other food allergies, early introduction of cow's milk before the digestive system is fully developed, and a personal history of atopic dermatitis. Most children outgrow cow's milk allergy by age 5, though some continue to have the allergy into adolescence and adulthood.
What happens if cow's milk allergy is left untreated?
If cow's milk allergy is left untreated and exposure to dairy continues, it can lead to repeated allergic reactions that may increase in severity over time, with each exposure potentially triggering more serious symptoms. Chronic exposure can cause persistent digestive problems, malnutrition, poor growth in children, and ongoing skin conditions like eczema that affect quality of life. The most serious risk is anaphylaxis, a life-threatening allergic reaction that can occur suddenly and requires immediate medical intervention with epinephrine. Untreated allergies can also lead to unnecessary dietary restrictions without proper guidance, potentially causing nutritional deficiencies, or conversely, continued exposure to hidden dairy ingredients that perpetuate symptoms and health problems.
Can cow's milk allergy be diagnosed with a blood test?
Yes, cow's milk allergy can be diagnosed with blood tests that measure specific IgE antibodies to milk proteins. These blood tests are safe, convenient, and particularly useful for people who cannot undergo skin prick testing due to severe eczema, taking antihistamines, or risk of severe reactions. Blood testing identifies the presence and levels of IgE antibodies to cow's milk, with elevated levels indicating an allergic response. The results should be interpreted alongside your symptom history and physical examination by a healthcare provider, as some people may have positive blood tests without clinical symptoms, while others may have negative tests despite true allergies.
How is cow's milk allergy treated?
The primary treatment for cow's milk allergy is strict avoidance of all milk and dairy products, including milk, cheese, yogurt, butter, cream, and any foods containing milk proteins. For infants, this means using special hypoallergenic formulas based on extensively hydrolyzed proteins or amino acids instead of regular cow's milk formula, while breastfeeding mothers must eliminate dairy from their own diets. People with cow's milk allergy should carry epinephrine auto-injectors for emergency treatment of severe reactions and wear medical alert identification. Working with an allergist and dietitian ensures proper nutrition while avoiding dairy, as calcium and vitamin D supplementation may be necessary to prevent deficiencies from eliminating dairy products.
How can I prevent cow's milk allergy?
While there is no guaranteed way to prevent cow's milk allergy, exclusive breastfeeding for the first 4-6 months of life may reduce the risk of developing food allergies in high-risk infants. Current recommendations suggest introducing solid foods, including dairy products, around 6 months of age rather than delaying introduction, as early exposure to potential allergens may actually help prevent allergies. For infants at high risk due to family history, consulting with a pediatric allergist before introducing cow's milk can help develop a safe introduction plan. Pregnant and breastfeeding mothers do not need to avoid dairy unless the infant has already shown signs of allergy, as avoidance during pregnancy has not been proven to prevent food allergies.
What can I do at home for cow's milk allergy?
At home, carefully read all food labels to identify and avoid milk proteins listed as casein, whey, lactose, curds, or any ingredient with the word milk or dairy. Keep your kitchen organized with separate utensils and cooking surfaces for dairy-free foods to prevent cross-contamination, and educate all family members and caregivers about the allergy and emergency response procedures. Stock your pantry with safe alternatives like plant-based milks made from soy, almond, oat, or rice, and ensure adequate calcium intake through fortified non-dairy products, leafy greens, and supplements if needed. Always keep prescribed epinephrine auto-injectors accessible and unexpired, train household members on how to use them, and establish clear emergency action plans for managing allergic reactions.
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Food Allergen Profile, IgE With Component Reflexes
Google reviews 505 reviews
$395 $308
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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