Congenital Rubella Syndrome Blood Test

What is Congenital Rubella Syndrome?

Congenital Rubella Syndrome (CRS) is a serious condition that occurs when a pregnant woman contracts rubella virus and passes it to her developing fetus, causing birth defects. It is caused by the rubella virus crossing the placenta during pregnancy, particularly in the first trimester. The Rubella Immune Status test is the most important test for preventing CRS because it determines if a woman has protective antibodies before or during pregnancy.

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What causes Congenital Rubella Syndrome?

Congenital Rubella Syndrome is caused by the rubella virus (also called German measles) when it infects a pregnant woman and crosses the placenta to infect the developing fetus. The virus is most dangerous during the first trimester of pregnancy when the baby's organs are forming. When a non-immune pregnant woman contracts rubella, the virus can cause severe birth defects including heart problems, deafness, blindness, intellectual disabilities, and damage to the liver and spleen.

What is the best test for Congenital Rubella Syndrome risk?

The Rubella Immune Status test is the most important test for preventing Congenital Rubella Syndrome because it measures rubella antibodies (IgG) in your blood to determine whether you have immunity protection. If the test shows low or absent antibodies, you lack protection and are at risk if you become pregnant and contract rubella. For comprehensive pregnancy planning, the Measles, Mumps, Rubella (MMR) Immunity Profile is also essential as it evaluates immunity to all three viruses at once and helps identify women who need vaccination before attempting pregnancy.

When should I get tested for rubella immunity?

You should get tested if you are planning to become pregnant, are in your childbearing years and unsure of your vaccination status, work in healthcare or childcare settings with potential rubella exposure, or are currently pregnant and have never had your immunity checked. Testing is especially important before pregnancy so you can receive the MMR vaccine if needed, as the vaccine cannot be given during pregnancy and you must wait at least one month after vaccination before conceiving.

What are the symptoms of Congenital Rubella Syndrome in babies?
Babies born with Congenital Rubella Syndrome may have multiple birth defects including congenital heart disease (particularly patent ductus arteriosus), cataracts or glaucoma causing vision problems, hearing loss or complete deafness, developmental delays and intellectual disabilities, low birth weight, liver and spleen enlargement, and a characteristic blueberry muffin rash at birth. Some symptoms may not be apparent immediately and can develop over the first few years of life, particularly hearing and vision problems.
Who is at risk for having a baby with Congenital Rubella Syndrome?
Women who lack immunity to rubella and become infected during pregnancy are at risk, especially those who were never vaccinated with the MMR vaccine or did not receive both required doses. Women born outside the United States in countries without routine rubella vaccination programs, those with weakened immune systems, and women who work in healthcare, schools, or childcare facilities with increased virus exposure face higher risk. The risk of fetal damage is highest when infection occurs in the first 12 weeks of pregnancy.
What happens if rubella infection during pregnancy is left untreated?
If a pregnant woman contracts rubella and it goes unrecognized or untreated, the virus will almost certainly cross the placenta and infect the fetus, causing severe and permanent birth defects. Up to 85% of babies whose mothers contract rubella in the first trimester will develop Congenital Rubella Syndrome with multiple organ system defects. Unfortunately, there is no treatment to reverse fetal damage once rubella infection occurs during pregnancy, which is why prevention through immunity testing and vaccination before pregnancy is absolutely critical.
Can Congenital Rubella Syndrome risk be diagnosed with a blood test?
Yes, blood tests are essential for assessing the risk of Congenital Rubella Syndrome. The Rubella Immune Status test measures IgG antibodies to determine if you have immunity from previous vaccination or infection. If you are pregnant and have been exposed to rubella, your doctor may order additional tests to detect IgM antibodies, which indicate recent or active infection. These blood tests help identify women who need vaccination before pregnancy or require close monitoring if exposed to rubella while pregnant.
How is Congenital Rubella Syndrome treated?
There is no cure for Congenital Rubella Syndrome once a baby is born with the condition, and treatment focuses on managing the specific birth defects and complications. Babies may need heart surgery for cardiac defects, hearing aids or cochlear implants for deafness, cataract surgery for vision problems, and early intervention services including physical therapy, speech therapy, and special education. Prevention through maternal immunity testing and vaccination before pregnancy is the only way to truly address CRS, as there is no treatment to prevent or reverse fetal damage once maternal infection occurs.
How can I prevent Congenital Rubella Syndrome?
The most effective prevention is getting tested for rubella immunity before pregnancy and receiving the MMR vaccine if you lack protection. You must wait at least one month after vaccination before trying to conceive. If you are already pregnant and not immune, avoid contact with anyone who has rubella or a rash illness, practice good hand hygiene, and alert your healthcare provider immediately if you are exposed to someone with rubella. Women who received only one dose of MMR vaccine as a child should get a second dose to ensure full immunity.
What can I do at home to protect against Congenital Rubella Syndrome?
The most important step you can take at home is to verify your vaccination records and get tested for rubella immunity if you are planning pregnancy or unsure of your status. Maintain good hygiene practices including frequent handwashing, especially if you are around children who may carry the virus. Avoid close contact with anyone showing signs of illness including rash, fever, or swollen lymph nodes. If you are pregnant and not immune, limit exposure to crowded places during rubella outbreaks and educate family members about the importance of their own MMR vaccination to create a protective environment around you.
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Long story short:
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  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
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Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
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During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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