HIV Co-infection Blood Test

What is Co-infection with HIV?

Co-infection with HIV refers to having HIV along with other infectious diseases simultaneously. It occurs because HIV weakens the immune system and shares transmission routes with pathogens like Hepatitis B and Hepatitis C viruses. The Hepatitis C Antibody with Reflex to HCV RNA Quantitative Real-Time PCR test is the most important test for detecting one of the most common HIV co-infections.

RECOMMENDED TEST Hepatitis C Antibody with Reflex to HCV, RNA, Quantitative, Real-Time PCR
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What causes HIV co-infection?

HIV co-infection is caused by acquiring HIV along with other infectious pathogens that share similar transmission routes. Common co-infections include Hepatitis B virus (HBV), Hepatitis C virus (HCV), tuberculosis bacteria (Mycobacterium tuberculosis), and sexually transmitted infections like syphilis (Treponema pallidum) and gonorrhea (Neisseria gonorrhoeae). These infections often occur together because they spread through unprotected sexual contact, sharing needles, or exposure to contaminated blood. HIV weakens your immune system, making you more vulnerable to acquiring and developing complications from these additional infections.

What is the best test for HIV co-infection?

The Hepatitis C Antibody with Reflex to HCV RNA Quantitative Real-Time PCR is the most important test for detecting HIV co-infection because Hepatitis C is one of the most common co-infections in people living with HIV. This comprehensive test first screens for Hepatitis C antibodies, and if positive, automatically performs quantitative RNA testing to confirm active infection and measure viral load. This two-step approach provides complete information about whether you have been exposed to Hepatitis C and if you currently have an active infection requiring treatment. Additional screening tests for Hepatitis B, tuberculosis, and sexually transmitted infections may also be recommended based on your risk factors and symptoms.

When should I get tested for HIV co-infection?

You should get tested if you have been diagnosed with HIV or have risk factors for both HIV and other blood-borne infections. Get tested immediately if you share needles for drug use, have unprotected sex with multiple partners, received a blood transfusion before 1992, or have unexplained symptoms like persistent fatigue, jaundice, or recurring infections. Regular screening is essential if you are living with HIV, as co-infections can accelerate disease progression and complicate treatment. Early detection through blood work allows your healthcare provider to develop a comprehensive treatment plan addressing all infections simultaneously.

What are the symptoms of HIV co-infection?
Symptoms of HIV co-infection vary depending on which additional infection is present. Hepatitis C co-infection may cause fatigue, jaundice (yellowing of skin and eyes), abdominal pain, and dark urine. Tuberculosis co-infection often presents with persistent cough, night sweats, weight loss, and fever. Sexually transmitted co-infections might cause unusual discharge, genital sores, or pelvic pain. Many people with co-infections experience no symptoms initially, which is why regular blood testing is crucial for anyone living with HIV or at risk for multiple infections.
Who is at risk for HIV co-infection?
People at highest risk include those who inject drugs and share needles, have unprotected sex with multiple partners, or have received blood products before modern screening practices. Healthcare workers exposed to contaminated needles or blood are also at increased risk. Men who have sex with men face elevated risk for HIV and co-infections with syphilis, gonorrhea, and Hepatitis B. Anyone living with HIV is automatically at higher risk for opportunistic infections due to their weakened immune system. Geographic location matters too, as tuberculosis co-infection is more common in areas with high TB prevalence.
What happens if HIV co-infection is left untreated?
Untreated HIV co-infection leads to faster disease progression and more severe complications than HIV alone. Hepatitis C co-infection accelerates liver damage, increasing the risk of cirrhosis and liver cancer. Tuberculosis can spread throughout your body, affecting your lungs, brain, and other organs. Untreated co-infections make HIV harder to control, as they increase viral load and reduce CD4 cell counts more rapidly. This creates a dangerous cycle where each infection worsens the other, compromising your immune system and reducing treatment effectiveness. Early detection through blood testing and prompt treatment significantly improve outcomes and life expectancy.
Can HIV co-infection be diagnosed with a blood test?
Yes, blood tests are the primary method for diagnosing HIV co-infections. The Hepatitis C Antibody test detects antibodies to HCV and reflexes to RNA testing if positive to confirm active infection. Hepatitis B surface antigen tests identify HBV infection, while syphilis screening uses antibody tests. Blood work can also detect markers of tuberculosis infection, though additional testing may be needed for confirmation. Comprehensive blood panels check your immune function through CD4 counts and viral load measurements, helping healthcare providers understand how co-infections are affecting your overall health and guide treatment decisions.
How is HIV co-infection treated?
Treatment for HIV co-infection involves managing both HIV and the additional infections simultaneously with a coordinated approach. Antiretroviral therapy (ART) controls HIV, while direct-acting antivirals treat Hepatitis C, often achieving cure rates over 95 percent. Hepatitis B may require long-term antiviral medications, and tuberculosis is treated with a combination of antibiotics for several months. Your healthcare provider carefully selects medications that work together without dangerous interactions. Regular blood testing monitors treatment effectiveness by measuring viral loads, liver function, and immune system recovery. Successful treatment of co-infections often improves HIV outcomes and overall health.
How can I prevent HIV co-infection?
Preventing HIV co-infection requires the same strategies that prevent HIV transmission. Use condoms consistently during sexual activity and never share needles or drug equipment. Get vaccinated against Hepatitis A and B, as vaccines are available for these infections. If you are living with HIV, take your antiretroviral medications as prescribed to maintain an undetectable viral load, which reduces transmission risk and protects your immune system. Regular blood testing helps detect co-infections early when treatment is most effective. Consider pre-exposure prophylaxis (PrEP) if you are at high risk for HIV, and practice harm reduction strategies if you inject drugs.
What can I do at home to support treatment for HIV co-infection?
Supporting your treatment at home starts with taking all medications exactly as prescribed and never missing doses. Avoid alcohol completely, as it accelerates liver damage, especially with Hepatitis co-infections. Eat a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to support your immune system and liver function. Get adequate sleep, manage stress through relaxation techniques, and stay physically active with moderate exercise. Avoid sharing personal items like razors or toothbrushes that might have blood on them. Keep all medical appointments and get recommended blood tests to monitor your progress and adjust treatment as needed.
How’s this work?
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Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

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Hepatitis C Antibody with Reflex to HCV, RNA, Quantitative, Real-Time PCR
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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