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Chronic HIV infection is the ongoing presence of the Human Immunodeficiency Virus in the body after the initial acute infection phase, lasting for many years without treatment. It is caused by HIV-1 or HIV-2 viruses that continue to replicate and attack CD4+ T cells, progressively weakening the immune system. The HIV 1/2 Antigen and Antibodies, Fourth Generation test is the most important test for confirming chronic HIV infection.
Chronic HIV infection is caused by the continued presence of HIV-1 or HIV-2 viruses in the body after the initial acute infection phase. These viruses target and destroy CD4+ T cells, which are crucial white blood cells that help your immune system fight infections. Without treatment, the virus continues to replicate throughout the body, gradually weakening your immune defenses over many years and eventually progressing to AIDS if left untreated.
The HIV 1/2 Antigen and Antibodies, Fourth Generation test is the most important test for chronic HIV infection because it detects both HIV antigens (proteins from the virus itself) and HIV antibodies (proteins your immune system produces in response to the infection). This comprehensive approach makes it highly accurate for confirming ongoing infection, as HIV antibodies remain present in the blood for life once infection has occurred. The test can identify both HIV-1 and HIV-2 strains, providing complete coverage for diagnosis and monitoring.
You should get tested if you have previously tested positive for HIV and need to confirm your ongoing status, if you have engaged in unprotected sex or shared needles in the past several months, if a sexual partner has disclosed they are HIV positive, or if you are experiencing persistent symptoms like unexplained weight loss, chronic fatigue, recurring fevers, or frequent infections. Regular testing every 3-6 months is recommended for people with ongoing risk factors, and annual testing is advised for sexually active adults.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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