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Chronic Hepatitis B infection is a long-term viral infection that affects the liver and persists for more than six months. It is caused by the Hepatitis B virus (HBV), which the immune system cannot effectively clear, leading to ongoing liver inflammation and potential complications. The Hepatitis B Surface Antigen (HBsAg) with Reflex Confirmation is the most important test for diagnosing chronic Hepatitis B infection.
Chronic Hepatitis B infection is caused by the Hepatitis B virus (HBV), which enters the bloodstream through contact with infected blood, sexual transmission, or from mother to baby during childbirth. When the immune system fails to clear the virus within six months, the infection becomes chronic and the virus continues to replicate in liver cells. Unlike acute infections that resolve on their own, chronic Hepatitis B persists because the immune system cannot mount an effective response to eliminate the virus completely, leading to ongoing liver inflammation and damage over time.
The Hepatitis B Surface Antigen (HBsAg) with Reflex Confirmation is the most important test for chronic Hepatitis B infection because it detects the presence of the virus in your bloodstream and confirms whether the infection has persisted beyond six months. When HBsAg remains positive for more than six months, it definitively indicates chronic infection. Additional tests like the Hepatitis B Core Antibody Total and Hepatitis Be Antibody help monitor viral activity and assess the stage of infection, while the Hepatitis B Surface Antibody tests determine if your immune system is producing protective antibodies, providing a comprehensive picture of your infection status and helping guide treatment decisions.
You should get tested if you have been previously diagnosed with acute Hepatitis B and it has been more than six months since your initial infection, if you have persistent fatigue or jaundice, or if you have risk factors such as being born in regions with high Hepatitis B prevalence or having a family history of the infection. Testing is also essential if you experience ongoing abdominal pain, dark urine, or unexplained liver enzyme elevations. Early detection through regular blood testing is crucial for monitoring liver health and preventing serious complications like cirrhosis and liver cancer.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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