Cardiovascular Disease Blood Test

What is Cardiovascular Disease?

Cardiovascular disease encompasses conditions affecting the heart and blood vessels, including coronary artery disease, heart attacks, and strokes. It is caused by atherosclerosis, where cholesterol and inflammatory substances accumulate in arterial walls, narrowing blood flow and increasing clot formation risk. The Lipid Panel is the most important test for cardiovascular disease diagnosis because it measures total cholesterol, HDL, LDL, and triglycerides that directly indicate heart disease risk.

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What causes cardiovascular disease?

Cardiovascular disease is caused by atherosclerosis, a process where cholesterol, calcium, and inflammatory substances accumulate inside artery walls, forming plaques that narrow blood vessels. This buildup restricts blood flow to the heart, brain, and other organs, increasing the risk of heart attacks and strokes. Major contributing factors include high LDL cholesterol, chronic inflammation, smoking, high blood pressure, diabetes, obesity, and genetic predisposition. The disease develops gradually over years as arterial damage worsens from oxidative stress and lipid deposits.

What is the best test for cardiovascular disease?

The Lipid Panel is the most important test for cardiovascular disease because it measures total cholesterol, HDL (good cholesterol), LDL (bad cholesterol), and triglycerides, providing essential information about heart disease risk. For more comprehensive assessment, the Cardio IQ Advanced Lipid Panel is the best advanced option because it measures LDL particle number and Lipoprotein (A), which are stronger predictors of heart attack risk than standard cholesterol numbers. Additionally, the C-Reactive Protein (CRP) High Sensitivity test is essential for detecting inflammation in blood vessels, while the Homocysteine Cardiovascular test identifies elevated levels of this amino acid that damages arterial walls and promotes blood clots.

When should I get tested for cardiovascular disease?

You should get tested if you have a family history of heart disease, high blood pressure, diabetes, or are over 40 years old. Testing is also important if you experience chest pain, shortness of breath during normal activities, unexplained fatigue, or have risk factors like smoking, obesity, or high stress levels. Anyone with existing heart disease should get regular blood work to monitor cholesterol, inflammation markers, and treatment effectiveness. Early detection through blood testing can identify risk factors before symptoms appear, allowing you to make lifestyle changes or start medications to prevent heart attacks and strokes.

What are the symptoms of cardiovascular disease?
Cardiovascular disease symptoms include chest pain or discomfort (angina), shortness of breath, fatigue, irregular heartbeat, dizziness, and pain in the neck, jaw, throat, or back. You might experience cold sweats, nausea, or pain radiating down your left arm. Some people have no symptoms until they suffer a heart attack or stroke. Warning signs of a heart attack include sudden intense chest pressure, difficulty breathing, and upper body pain, while stroke symptoms include sudden numbness, confusion, trouble speaking, vision problems, and severe headache. Many people with early cardiovascular disease feel fine, which is why blood testing is crucial for detecting problems before they become life-threatening.
Who is at risk for cardiovascular disease?
People at highest risk include those over 45 for men and over 55 for women, individuals with family history of heart disease, smokers, and those with high blood pressure or diabetes. Your risk increases if you have high cholesterol, are overweight or obese, live a sedentary lifestyle, experience chronic stress, or have sleep apnea. Men generally develop cardiovascular disease earlier than women, but women's risk increases significantly after menopause. Race and ethnicity also play a role, with African Americans, Hispanic Americans, and Native Americans facing higher risk. People with autoimmune conditions like lupus or rheumatoid arthritis also have elevated cardiovascular disease risk due to chronic inflammation.
What happens if cardiovascular disease is left untreated?
Untreated cardiovascular disease progressively worsens, leading to heart attacks, strokes, heart failure, and sudden cardiac death. As arteries become more blocked, your heart muscle receives less oxygen, causing permanent damage that weakens your heart's pumping ability. You may develop arrhythmias (irregular heartbeats) that can be fatal, or experience aneurysms where weakened artery walls bulge and potentially rupture. Reduced blood flow to your brain increases stroke risk, which can cause permanent disability, speech problems, paralysis, or death. Untreated disease also affects your kidneys, legs, and other organs, leading to kidney failure, peripheral artery disease, and gangrene requiring amputation. Early detection and treatment through blood testing and lifestyle changes can prevent these devastating complications.
Can cardiovascular disease be diagnosed with a blood test?
Yes, blood tests are essential for diagnosing cardiovascular disease risk and monitoring heart health, though they are typically combined with physical exams, blood pressure measurements, and imaging tests for complete evaluation. The Lipid Panel detects high cholesterol levels that cause arterial blockages, while the C-Reactive Protein test reveals inflammation damaging your blood vessels. Advanced tests like the Cardio IQ Advanced Lipid Panel measure LDL particle number and Lipoprotein (A), providing more accurate risk prediction than standard tests. Blood tests for homocysteine, fibrinogen, TMAO, and omega-3 fatty acids identify additional risk factors that contribute to heart disease. While blood tests cannot show physical blockages in arteries (which require imaging), they detect the biochemical abnormalities that cause cardiovascular disease years before symptoms appear.
How is cardiovascular disease treated?
Cardiovascular disease treatment includes lifestyle changes, medications, and sometimes procedures or surgery. Lifestyle modifications include eating a heart-healthy diet low in saturated fats and high in fruits, vegetables, and whole grains, exercising regularly, quitting smoking, maintaining a healthy weight, and managing stress. Medications may include statins to lower cholesterol, blood pressure medications, aspirin or other blood thinners to prevent clots, and beta-blockers to reduce heart workload. For advanced disease, procedures like angioplasty with stent placement open blocked arteries, while bypass surgery creates new routes for blood flow around blockages. Regular blood testing monitors treatment effectiveness and helps your doctor adjust medications to achieve optimal cholesterol, inflammation, and other biomarker levels.
How can I prevent cardiovascular disease?
You can prevent cardiovascular disease by maintaining healthy cholesterol and blood pressure levels through diet, exercise, and weight management. Eat a Mediterranean-style diet rich in fish, nuts, olive oil, fruits, and vegetables while limiting red meat, processed foods, and added sugars. Exercise at least 150 minutes weekly with activities like brisk walking, swimming, or cycling. Quit smoking and limit alcohol to moderate amounts. Manage diabetes carefully if you have it, and control stress through meditation, yoga, or other relaxation techniques. Get regular blood tests to monitor your cholesterol, inflammation markers, and other cardiovascular risk factors so you can make adjustments before problems develop. Taking omega-3 supplements and maintaining healthy vitamin levels also supports heart health.
What natural remedies help with cardiovascular disease?
Natural approaches that support heart health include omega-3 fatty acids from fish oil, which reduce inflammation and triglycerides. Coenzyme Q10 supports energy production in heart cells and may improve heart function, especially if you take statins. Garlic can modestly lower cholesterol and blood pressure, while plant sterols and stanols block cholesterol absorption. Fiber from oats, beans, and flax seeds helps reduce LDL cholesterol. Green tea contains antioxidants that protect blood vessels, and dark chocolate in moderation provides flavonoids that improve circulation. However, natural remedies should complement, not replace, medical treatment and lifestyle changes. Always get regular blood testing to monitor your heart health markers and consult your doctor before adding supplements, as some can interact with heart medications.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

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